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Asian Journal of Andrology
Scopus
ISSN 1008-682X · Wolters Kluwer Medknow Publications · 1.627 artikel di indeks
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Artikel Jurnal
Locally advanced prostate cancer treated with neoadjuvant therapy combined with surgery: a multicenter retrospective cohort analysis
Recent data from clinical trials have shown that neoadjuvant therapies significantly improve the pathological outcomes of prostate cancer patients. This study aimed to assess the specific pathological and prognostic effects of these therapies in a real-world, multicenter cohort. Additionally, we…
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Artikel Jurnal
ZhongdaChat-ED: a medical large language model for personalized erectile dysfunction health consultation and professional clinical decision-making using retrieval-augmented generation
Artificial intelligence (AI)-driven large language models (LLMs) hold potential for medical applications but face challenges, such as inaccurate or outdated training data. In this study, ZhongdaChat-ED, a personalized medical LLM integrating retrieval-augmented generation (RAG) technology, was…
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Artikel Jurnal
Excellent long-term device survival of inflatable penile prosthesis over 27 years
The study aimed to assess the long-term device survival of a 3-piece inflatable penile prosthesis (PP) in patients with erectile dysfunction (ED). This retrospective observational longitudinal study involved patients with drug-refractory ED who underwent primary 3-piece inflatable PP implantation…
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Artikel Jurnal
Assessing post-marketing safety of PDE5Is in erectile dysfunction: real-world evidence from the FDA adverse event reporting system
Erectile dysfunction (ED) is a common condition affecting men worldwide. The U.S. Food and Drug Administration (FDA) has approved phosphodiesterase type 5 inhibitors (PDE5Is), including sildenafil, tadalafil, vardenafil, and avanafil, for treating ED. However, real-world studies on adverse events…
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The dark side of transurethral access for LUTS/BPH surgery: a narrative review
The transurethral route is the access of choice for benign prostatic hyperplasia (BPH) surgical treatment. Transurethral resection of the prostate (TURP) has been the gold standard in surgical intervention for BPH; however, the advent of novel surgical techniques and the exploration of new energy…
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Artikel Jurnal
From non-clinically significant to clinically significant prostate cancer: identifying predictors of discrepancy from biopsy to radical prostatectomy
Accurate classification between non-clinically significant prostate cancer (non-csPCa) and clinically significant prostate cancer (csPCa) is essential for effective risk stratification and optimal management of prostate cancer. This study aimed to evaluate the consistency between preoperative and…
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Artikel Jurnal
Ginsenoside Rb1 mitigates diabetes-induced erectile dysfunction in rats by reducing oxidative stress and modulating the PI3K/AKT/eNOS pathway
Erectile dysfunction is a complex and prevalent complication of diabetes, and effective treatments are lacking. Oxidative stress, fibrosis, and apoptosis are closely associated with the development of diabetes mellitus-related erectile dysfunction (DMED). Notably, ginsenoside Rb1 (Rb1) exerts…
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Artikel Jurnal
Inhibition of the PI3K/AKT signaling pathway blocks the oncogenic activity of TRIM26 in prostate cancer cells
The tripartite motif-containing protein 26 (TRIM26) is an E3 ubiquitin ligase with strong oncogenic activity in various cancers. However, its role and molecular mechanism in prostate cancer (PCa) remain elusive. To clarify its role in promoting PCa progression, we evaluated TRIM26 expression in…
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Artikel Jurnal
Perioperative therapies and techniques to enhance penile dimensional and functional outcomes following inflatable penile prosthesis implantation: a contemporary 10-year systematic review
Implantation of inflatable penile prosthesis should be considered as a definitive treatment of erectile dysfunction. However, the sole procedure might not allow for optimal dimensional and functional outcomes. The aim of this study was to systematically review the literature and present the…
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Artikel Jurnal
Penile implant reservoir placement methods: is there a gold standard?
Erectile dysfunction (ED), a condition affecting nearly 150 million men worldwide, is expected to impact over 300 million by 2025. Phosphodiesterase type 5 inhibitors (PDE5Is) remain the first-line treatment for ED, yet a subset of patients exhibit inadequate responses. For these individuals, the…
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Artikel Jurnal
Update on penile prosthesis
The aim of this narrative review is to provide a comprehensive overview of penile prostheses (PPs) for the treatment of erectile dysfunction (ED), exploring their historical evolution, types, key advancements, clinical outcomes, and future directions. A comprehensive literature search of studies…
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Artikel Jurnal
Near-infrared photobiomodulation therapy for age-related erectile dysfunction: molecular and physiological restoration in a mouse model
Age-related erectile dysfunction (ARED) represents a significant clinical challenge due to the interplay between chronic comorbidities and age-related physiological decline. This study investigated the therapeutic potential of near-infrared photobiomodulation therapy (NIR-PBMT) in ARED mice…
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Artikel Jurnal
An update on penile prostheses: a narrative review
Men with erectile dysfunction offered penile prostheses have high satisfaction rates when properly counselled. These devices have undergone significant advancements in design, surgical techniques, and perioperative management, enhancing patient outcomes, satisfaction, and safety. This review…
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Artikel Jurnal
Urgent need for inclusion of male infertility in global health strategies: insights from the GBD 2021 Study
This study examines the global burden and prevalence of male infertility using data from the Global Burden of Disease Study 2021 (GBD 2021 Study), encompassing 204 countries from 1990 to 2021. By analyzing disability-adjusted life years (DALYs) and prevalence trends, alongside lifestyle…
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Artikel Jurnal
Advancements in penile lengthening techniques concurrent with penile prosthesis placement: a narrative review
Penile prosthetic devices stand as the foremost solution for medication-resistant erectile dysfunction. Frequently, medical conditions triggering erectile dysfunction also led to penile shortening, detrimentally impacting patients’ quality of life. This narrative review aims to explore and evaluate…
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Artikel Jurnal
Clinical features and genetic analysis of androgen receptor gene variants in 30 prepubertal patients with androgen insensitivity syndrome
Androgen insensitivity syndrome (AIS; Online Mendelian Inheritance in Man [OMIM; #300068]) is an X-linked recessive disorder caused by pathogenic variants in the androgen receptor (AR) gene located in the Xq11-q13 region. In this retrospective study of 30 patients with AIS, next-generation…
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