2.718 hasil
Menampilkan 1–20 · 0,29 detik · RSS
Chinese Journal of Lung Cancer
Scopus
ISSN 1009-3419 · Chinese Anti-Cancer Association; Chinese Antituberculosis Association · 2.718 artikel di indeks
-
Artikel Jurnal
A Case of EGFR-mutant Lung Adenocarcinoma with Secondary SCLC Transformation and ALK Fusion after Osimertinib Treatment
Epidermal growth factor receptor (EGFR) gene mutations are the most common driver mutations in non-small cell lung cancer (NSCLC). This article reports a case of a patient with EGFR-sensitive mutant lung adenocarcinoma who developed secondary transformation to small cell lung cancer (SCLC) and…
-
Artikel Jurnal
Ziyuglycoside II Inhibit the Progression of Non-small Cell Lung Cancer through the ITGB4/FAK Signaling Pathway
Background and objective The incidence and mortality rates of non-small cell lung cancer (NSCLC) are generally on the rise, and the overall prognosis of patients remains poor. Current clinical treatment strategies have significant limitations. Notably, the bioactive components of traditional…
-
Artikel Jurnal
Potential Mechanisms and Research Advances of HDAC1 in Lung Cancer
Lung cancer is the malignant tumor with the highest incidence and mortality rate worldwide. The current treatment methods have limited efficacy, and the prognosis of patients is poor. There is an urgent need to explore new therapeutic targets and strategies. Epigenetic modification disorders are…
-
Artikel Jurnal
Mechanisms of Macrophage Efferocytosis-driven Remodeling of Lung Cancer Microenvironment Structure and Angiogenesis and Prospects for Clinical Intervention
Lung cancer is one of the most prevalent and lethal malignant tumors worldwide. In recent years, immune checkpoint inhibitors have significantly improved the survival outcomes of some patients with advanced non-small cell lung cancer; however, primary and acquired resistance remain important…
-
Artikel Jurnal
Glycolytic Reprogramming in Lung Adenocarcinoma: Molecular Mechanisms, Metabolic Biomarkers and Targeted Therapeutic Strategies
Lung adenocarcinoma (LUAD) is the most common and highly aggressive subtype of non-small cell lung cancer, characterized by metabolic reprogramming with enhanced glycolysis. Upregulation of key glycolytic enzymes [hexokinase 2 (HK2), pyruvate kinase M2 (PKM2), lactate dehydrogenase A (LDHA)] and…
-
Artikel Jurnal
Chinese Expert Consensus on Delta-like Ligand 3-T Cell Engager Therapy for SCLC
Small cell lung cancer (SCLC), characterized by high aggressiveness, early metastasis, and poor prognosis, has long been a major challenge in lung cancer treatment. In recent years, the advent of immune checkpoint inhibitors (ICIs) has significantly improved overall survival in patients with SCLC…
-
Artikel Jurnal
Effects of LINC00641 on the Malignant Progression and Chemotherapy Resistance of Non-small Cell Lung Cancer H1299 Cells by Regulating the miR-1306-5p/FGFR3 Axis
Background and objective Non-small cell lung cancer (NSCLC) is one of the causes of cancer-related deaths worldwide. Although platinum-based chemotherapy is the main treatment method for advanced patients, acquired resistance often leads to treatment failure. Long non-coding RNAs (lncRNAs) play an…
-
Artikel Jurnal
Research Advances in ctDNA-MRD Monitoring in Local Treatment for Non-small Cell Lung Cancer
Non-small cell lung cancer (NSCLC) remains at risk of recurrence after local treatment, and early identification of molecular residual disease before radiological progression is an important issue in risk stratification. Circulating tumor DNA (ctDNA)-based molecular residual disease (MRD)…
-
Artikel Jurnal
Abnormally Elevated Procalcitonin in Stage IV Lung Adenocarcinoma with Neuroendocrine Differentiation: A Case Report and Literature Review
Procalcitonin (PCT) is a key biomarker widely used in clinical practice for the diagnosis of bacterial infection, assessment of antimicrobial efficacy, and prognostic evaluation. Studies have shown that PCT can also be elevated in various malignancies, correlating closely with tumor progression…
-
Artikel Jurnal
China Wumeng Mountain Lung Cancer: Evidence Chain, Clinical and Molecular Characteristics of Regional Lung Cancer Related to Coal Pollution in the Yunnan-Guizhou Plateau
Background and objective Long-term household coal burning, differences in coal sources and mineral compositions, energy structure, and socioeconomic conditions jointly constitute the regional exposure basis for lung cancer. This study conducts a multi-sectional, multi-dimensional and multi-omics…
-
Artikel Jurnal
Detection Status and Cost Analysis of Community Pulmonary Nodule Screening with Mobile LDCT Combined with AI
Background and objective Lung cancer is the malignant tumor with the highest morbidity and mortality in China. Low-dose computed tomography (LDCT) is the core method for early lung cancer screening, but traditional fixed-institution screening has the problem of insufficient accessibility at the…
-
Artikel Jurnal
Research Progress on Molecular Mechanisms and Precision Diagnosis and Treatment of Spinal Organotropic Metastasis in Lung Adenocarcinoma
Lung adenocarcinoma (LUAD) is the most common subtype of non-small cell lung cancer (NSCLC), with a high incidence of spinal metastasis and poor prognosis. Spinal metastasis of LUAD is not merely a simple bone metastasis but a directed metastasis process mediated by the anatomical characteristics…
-
Artikel Jurnal
Standardized Construction of Lung Cancer Organoids and Their Application Progress in the Precise Treatment of Lung Cancer
Lung cancer is the malignancy with the highest incidence and mortality rates in China. Although significant progress has been made in its treatment due to the application of various novel therapeutic approaches, challenges remain in early diagnosis, as more than half of patients present with…
-
Artikel Jurnal
Advances in the Growth Risk Assessment and Precision Management of Pulmonary Subsolid Nodules
Pulmonary subsolid nodules (SSNs) exhibit heterogeneous growth patterns. Most SSNs remain stable or grow only slowly during long-term follow-up, whereas a small subset grows rapidly over a relatively short period. Some of these lesions may ultimately progress to invasive adenocarcinoma (IAC)…
-
Artikel Jurnal
Perioperative Safety Analysis of Preoperative Targeted Therapy in Patients with ALK-positive Non-small Cell Lung Cancer
Background and objective Perioperative management of locally advanced non-small cell lung cancer (NSCLC) remains a significant clinical challenge. Although anaplastic lymphoma kinase-tyrosine kinase inhibitors (ALK-TKIs) have established a definitive role in the adjuvant setting for ALK-positive…
-
Artikel Jurnal
Ileal Perforation Caused by Pleural Mesothelioma-related Small Intestinal Involvement: A Case Report and Literature Review
Pleural mesothelioma (PM) usually manifests as local intrathoracic invasion, and small intestinal involvement is rare. A 37-year-old man with initially diagnosed stage IV diffuse PM and no definite history of asbestos exposure or other specific occupational or environmental exposure except for…
-
Artikel Jurnal
Research Advances in the Pulmonary Carcinogenic Effects of Atmospheric Fine Particulate Matter Mediated by GPER
Lung cancer remains the leading cause of cancer-related death worldwide. Fine particulate matter (PM2.5), classified as a group I human carcinogen, has been extensively linked to lung cancer development through epidemiological studies. The G protein-coupled estrogen receptor (GPER) can be activated…
-
Artikel Jurnal
Tumor Cell and Brain Microenvironment Interactions in Non-small Cell Lung Cancer Brain Metastasis: Mechanisms and Emerging Insights
Brain metastasis in non-small cell lung cancer (NSCLC) is shaped by continuous interactions between tumor cells and the brain-specific microenvironment. Vascular, glial and immune components contribute to intracranial colonization, immune escape and therapeutic resistance, while single-cell and…
-
Artikel Jurnal
State Changes and Stability Grading of Driver Genes in Non-small Cell Lung Cancer Based on Repeated NGS Testing
Background and objective Next-generation sequencing (NGS)-based driver gene testing has become a routine component of molecular subtyping and precision therapy for non-small cell lung cancer (NSCLC). Dynamic genomic monitoring facilitates early detection of resistance-related molecular alterations…
-
Artikel Jurnal
Digital Drainage Systems in Postoperative Chest Tube Management after Pulmonary Resection: Current Status and Future Perspectives
Chest drainage management is an essential component of perioperative care after pulmonary resection, aiming to evacuate intrapleural air and fluid and promote lung re-expansion. However, conventional chest drainage systems mainly rely on manual observation, making continuous and quantitative…
Menampilkan maksimal 50 halaman. Persempit pencarian dengan filter untuk hasil yang lebih spesifik.