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Applied and Environmental Microbiology
Scopus
ISSN 1098-5336 · American Society for Microbiology · 1.151 artikel di indeks
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Artikel Jurnal
Combined computational, rational, and empirical design of boiling-resistant keratinase
ABSTRACT Engineering of highly thermostable keratinase is of great theoretical interest in understanding protein stability mechanisms and practical significance for processing keratinous wastes such as feathers and wool. The thermostable subtilisin-like protease C2 is the major keratinase secreted…
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Artikel Jurnal
Deletion of tonB1 in Pseudomonas aeruginosa impairs zinc homeostasis and pathogenicity
ABSTRACT Many bacterial pathogens must acquire metal ions for proliferation and pathogenesis. In gram-negative bacteria, the TonB system is crucial for nutrient uptake. Previous research indicates that Pseudomonas aeruginosa uses the energy transduction protein TonB1 for iron uptake. Although zinc…
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The human skin microbiome remains unchanged after 24 h of sunscreen application
ABSTRACT To ensure safe, long-term use, topical products should be investigated to understand how they interact with the resident skin microbiota to mitigate potential risk. Sunscreens are essential for protecting skin from UV damage, but their effects on skin-resident microbes have not been well…
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Discovery of MBL-AB01: a novel antibacterial xanthone antibiotic with high activity against methicillin-resistant Staphylococcus aureus
ABSTRACT A novel compound denoted MBL-AB01 was isolated from a marine Actinoalloteichus, which belongs to a rare and underexplored class of Actinobacteria. This work demonstrates that the novel compound MBL-AB01 shows very high activity in vitro against six methicillin-resistant Staphylococcus…
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The interplay between the marine diazotroph Vibrio diazotrophicus and its prophage shapes both biofilm structure and nitrogen release
ABSTRACT Marine environments are frequently oligotrophic, characterized by low amount of bioassimilable nitrogen sources. At the global scale, the microbial fixation of N₂, or diazotrophy, represents the primary source of fixed nitrogen in pelagic marine ecosystems, playing a key role in supporting…
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Artikel Jurnal
Microbial source tracking of human and animal fecal contamination in Ecuadorian households
ABSTRACT Exposures to both human and animal feces pose human health risks, particularly for young children in low- and middle-income country (LMIC) settings where domestic animals are common, water and sanitation infrastructure is often limited, and enteropathogen transmission is high. Microbial…
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Characterization of plasmalogen production in facultative anaerobic bacteria and aerobic synthesis in recombinant Escherichia coli expressing anaerobic bacterium-derived plasmalogen synthase genes
ABSTRACT Plasmalogens are glycerophospholipids with vital physiological functions, conferring antioxidant properties and contributing to membrane stabilization. While plasmalogen synthase genes plsA and plsR were identified in the obligate anaerobic bacterium Clostridium perfringens, plasmalogen…
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Microbial interactions in facilitating antibiotic activity and resistance evolution
ABSTRACT In polymicrobial communities, microorganisms do not exist in isolation but engage in complex and dynamic interactions. Emerging evidence indicates that these microbial interactions can profoundly influence key aspects of antibiotic action, including antibiotic activity and the emergence…
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Linguistic bias and the hidden costs of science lost in translation
ABSTRACT English has become the global language of science, but this dominance has a cost. Researchers who are not native English speakers face invisible hurdles: efforts to learn and use a second language, obstacles to research dissemination, and diminished professional visibility. These barriers…
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Establishing conserved biosynthetic gene clusters of the phylum Myxococcota
ABSTRACT A surge in sequenced myxobacteria catalyzed by advancements in long-read genome and metagenome sequencing has provided sufficient data to scrutinize the conserved biosynthetic gene clusters (BGCs) within the phylum Myxococcota. Provided the utility of myxobacteria in environmental nutrient…
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A reverse transcription-quantitative polymerase chain reaction system for evaluating intestinal butyrate production by fecal bacteria
ABSTRACT Intestinal butyrate is key in maintaining host health. As an indicator of butyrate production, the fecal butyrate concentration is used for assessing health status; however, it may not be a suitable marker as it only accounts for residual fecal butyrate following intestinal absorption…
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A pentose, as a cytosine nucleobase modification in Shewanella phage Thanatos genomic DNA, mediates enhanced resistance toward host restriction systems
ABSTRACT Co-evolution of bacterial defense systems and phage counter-defense mechanisms has resulted in an intricate biological interplay between bacteriophages and their prey. In order to evade nuclease-based mechanisms that target DNA, various bacteriophages modify their nucleobases, which…
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Effects of aquaculture practices on Vibrio population dynamics and oyster microbiome
ABSTRACT Oyster aquaculture is essential for ensuring a sustainable food source. Despite stringent controls, cases of oyster-related illnesses linked to pathogenic Vibrio parahaemolyticus (Vp) and Vibrio vulnificus (Vv) persist. This study investigated the impact of aquaculture practices on the…
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Metabolomic and metagenomic insights into WFBG-mediated regulation of gut microbiota and metabolism in broilers
ABSTRACT The steady state of gut microbiota is a key factor in regulating the growth of broilers. The regulatory role of wet-fermented brewer’s grain (WFBG) in broiler gut development and microbiota is still elusive. In this study, non-targeted metabolomics and 16S rRNA sequencing analysis were…
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GSNOR is essential for nitric oxide homeostasis and involved in aflatoxin biosynthesis and pathogenicity in Aspergillus flavus
ABSTRACT Nitric oxide (NO) is an important biological signaling molecule. S-nitrosoglutathione reductase (GSNOR), a master regulator of NO signaling, regulates various biological processes. However, little is known about the role of GSNOR in Aspergillus flavus. Here, we identified a gene encoding…
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From currents to water masses: fine-scale insights into microbial biogeography in the Kuroshio–Oyashio Extension region
ABSTRACT The Kuroshio–Oyashio Extension (KOE) region is a highly variable region in the North Pacific Ocean, characterized by strong environmental gradients and multi-scale oceanographic processes. However, the fine-scale impact of these currents and associated water masses on microbial communities…
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The plasmid-host fitness landscape: a new paradigm for predicting the fate of mobile resistance
ABSTRACT The widespread persistence of antimicrobial resistance (AMR) plasmids presents a fundamental challenge to microbial evolution, known as the “plasmid paradox”: if these plasmids cause fitness cost, why are they not eliminated by selection? The classical view, which imposed a fixed generic…
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Quantitative microbial risk assessment of antibiotic resistance genes and mobile genetic elements in orchard soils across South Korea
ABSTRACT Antibiotic resistance is a global health crisis, but environmental pathways of resistance dissemination to farm workers remain poorly understood. Agricultural soils represent critical but underexplored reservoirs of antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs)…
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Artikel Jurnal
Efficient resuscitation of early-stage viable but non-culturable cells of Vibrio cholerae using treatment with proteolytic enzymes
ABSTRACT Vibrio cholerae, the etiological agent of cholera, is ubiquitous in environmental brackish waters. Exposure to low water temperatures induces the bacterium to enter a viable but non-culturable (VBNC) state. In this study, a stepwise decrease in water temperature to 4°C was found to delay…
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Artikel Jurnal
Soil pH and nitrate shape deterministic assembly of microbial communities in agricultural soils via Nitrososphaeria
ABSTRACT Understanding the assembly mechanisms of soil microbial communities is critical for maintaining nitrogen cycling in agricultural ecosystems, which underpins soil fertility and sustains crop productivity. While environmental filtering and biotic interactions shape these communities, our…
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