555 hasil
Menampilkan 1–20 · 0,49 detik · RSS
The Egyptian Journal of Internal Medicine
ISSN 1110-7782 · SpringerOpen · 555 artikel di indeks
-
Artikel Jurnal
Fasting salivary pepsin level as a reliable non-invasive method of screening for laryngopharyngeal reflux in Egyptian patients
Abstract Background Laryngopharyngeal reflux (LPR) is caused by the regurgitation of gastric contents above the upper esophageal sphincter. Diagnostic gold standard tests like multichannel intraluminal impedance (MII) and 24-h dual-probe pH-metry are invasive and expensive which limits their…
-
Artikel Jurnal
High-performance liquid chromatography local reference ranges of hemoglobin fractions (HbA, HbA2, and HbF) in detection of hemoglobinopathies in western Kenya
Abstract Background Western Kenya, being a malaria-endemic region, has a high prevalence of hemoglobinopathies mostly sickle cell and thalassemia. The hemoglobin fractions or variants, HbA, HbA2, and HbF, serve as biomarkers for the detection of hemoglobinopathies and are commonly used in…
-
Artikel Jurnal
Current update on herbal sources of antithrombotic activity—a comprehensive review
Abstract Background Herbs are commonly used to treat cardiovascular diseases in various traditional medicine. On the other hand, herb-drug interactions are most commonly encountered with conventional antiplatelet and anticoagulant drug prescriptions. This review presents a compilation of plants…
-
Artikel Jurnal
Use of cefepime, meropenem, or piperacillin/tazobactam as initial treatment for febrile neutropenia in patients with hematological malignancy — a real-life experience
Abstract Background Antimicrobials like fourth-generation cephalosporins, carbapenems, or β-lactams are widely used in treatment of febrile neutropenia (FN). The present study aimed to compare the efficacy of cefepime, meropenem, and piperacillin/tazobactam as initial treatment for chemo-induced FN…
-
Artikel Jurnal
Association of thrombosis and mortality in patients with COVID-19 infections: a hospital-based observational study
Abstract Objective A hospital-based cross-sectional study on COVID-19 confirmed patients was conducted at the Aga Khan University Hospital, Karachi, Pakistan, from April to June 2021. Presence of thrombosis in these patients was compared with mortality. Platelet counts and D-dimer was also compared…
-
Artikel Jurnal
Two years of SARS-CoV-2 infection (2019–2021): structural biology, vaccination, and current global situation
Abstract The deadly SARS-CoV-2 virus has infected more than 259,502,031 confirmed cases with 5,183,003 deaths in 223 countries during the last 22 months (Dec 2019–Nov 2021), whereas approximately 7,702,859,718, vaccine doses have been administered (WHO: https://covid19.who.int/ ) as of the 24th of…
-
Artikel Jurnal
Does pathological type of primary nephrotic syndrome affect serum concentrations of proprotein convertase subtilisin/kexin type 9?
Abstract Background Dyslipidemia is a common finding in primary nephrotic syndrome (PNS). Serum PCSK9 level is also increased in PNS and is the main cause of dyslipidemia in such patients. There is a paucity of data on the relation between dyslipidemia and pathological types of PNS. We hypothesized…
-
Artikel Jurnal
PPI efficacy in the reduction of variceal bleeding incidence and mortality, a meta-analysis
Abstract Objective To review the efficacy and safety of proton pump inhibitors (PPIs) in gastroesophageal varices (GEVs). Methods We searched PubMed MEDLINE, Scopus, and Web of Science for studies that measured the effect of PPI for prophylaxis and treatment of post-band ligation ulcers up to July…
-
Artikel Jurnal
The prevalence of ultra-low total IgE level among Egyptian population: impact of age, sex, and socioeconomic class
Abstract Background Immunoglobulin E (IgE) is the least prevalent antibody type; it plays a key role in host immunity against parasitic infections and allergic diseases. Association between IgE deficiency and higher malignancy rates has been suggested in many studies. Objectives The goal of our…
-
Artikel Jurnal
Distribution of hemoglobinopathy phenotypes in western Kenya: a retrospective study done at Aga Khan Hospital, Kisumu
Abstract Background Hemoglobinopathies are inheritable disorders of hemoglobin and are the most common genetic defects in humans. This is a neglected public health problem whose undiagnosis remain a major threat to its prevention and control in sub-Saharan Africa countries; thus its exact magnitude…
-
Artikel Jurnal
MicroRNA 21as a novel biomarker in hepatitis C virus-related hepatocellular carcinoma
Abstract Background Hepatocellular carcinoma is considered one of the most common cancers occurring in human population all over the world. It became an increasingly threatening malignancy due to both morbidity and mortality. Chronic viral hepatitis B and hepatitis C are two risk factors, which…
-
Artikel Jurnal
Interplay of serum hepcidin with female sex hormones, metabolic syndrome, and abdominal fat distribution among premenopausal and postmenopausal women
Highlights • Postmenopausal state (PMS) and metabolic syndrome (MetS) are independent factors of high hepcidin. • Estrogen and progesterone are correlated with hepcidin but not explain its higher level in PMS. • Ferritin, insulin resistance, and MetS are main contributors of high hepcidin in PMS. •…
-
Artikel Jurnal
Myelofibrosis treatment history and future prospects
Abstract Myelofibrosis (MF) is a haematopoietic stem cell tumour caused by the lack of BCR-ABL translocation due to point mutations in Janus kinases (JAKs). In previous years, dealing with MF included several protocols such as traditional drugs that control general symptoms, splenectomy, blood…
-
Artikel Jurnal
A young soldier with Susac syndrome: a case report
Abstract Background Susac syndrome is a rare disease with multisystem manifestations. While the exact pathogenesis is not known, it has been proposed to be an autoimmune endotheliopathy affecting the microvasculature of the brain, retina, and inner ear. The disease is characterized by a triad of…
-
Artikel Jurnal
Role of Vestibular Evoked Myogenic Potential (VEMP) in diagnosis of vestibular abnormalities in patients with type 2 diabetes mellitus
Abstract Objectives To evaluate the role of ocular vestibular evoked myogenic potentials (oVEMP) in diagnosis of vestibular abnormalities among patients with type 2 diabetes mellitus (T2DM). Methods Eighty T2DM patients were selected for the study plus a group of 30 normal non-diabetic individuals…
-
Artikel Jurnal
Effect of dietary synbiotic supplementation on serum indoxyl sulfate in prevalent hemodialysis patients
Abstract Background Indoxyl sulfate (IS) is produced by action of the intestinal flora on tryptophan in protein diet, and it is normally excreted by the kidney. IS is a protein-bound uremic toxin, and it is difficult to be removed by conventional hemodialysis (HD) methods; so, it accumulates in HD…
-
Artikel Jurnal
Acute poisoning of copper sulfate: a case report and review literature
Abstract Background Copper sulfate is a bright blue crystal used primarily for agricultural purposes, as a pesticide, disinfectant, feed, and soil additive. Acute volunteer poisoning of copper sulfate is not common in the world and in Iran. Case presentation We reported the case of a 15-year-old…
-
Artikel Jurnal
Isolated bone marrow sarcoidosis presenting as fever of unknown origin in a case of chronic myeloid leukemia
Abstract Background Isolated involvement of bone marrow in sarcoidosis has not been reported commonly. Sarcoidosis is a systemic granulomatous disease of unknown origin, characterized by the presence of non-caseating granulomatous lesions. There should be high index of suspicion in patients having…
-
Artikel Jurnal
The effect of non-invasively obtained central blood pressure on cardiovascular outcome in diabetic patients in Assiut University Hospitals
Abstract Background The major cause of morbidity and mortality in diabetes is cardiovascular disease, which is exacerbated by the presence of hypertension. Therefore, proper control of BP in diabetic hypertensive patients is essential. Few studies have specifically investigated the prognostic…