544 results

Net Present Value Impact of FDA’s Phase 3 Waivers on Monoclonal Antibody Biosimilar Development

Ranbhor R; Kulkarni P

Biologics: Targets & Therapy, Vol. Volume 20 No. Issue 1 · 2026 · English · DOAJ Scopus

Ranjit Ranbhor,1 Priyanka Kulkarni2 1Business Development, Portfolio and Patents, Odin Pharmaceuticals LLC, Somerset, NJ, USA; 2Feliciano School of Business, Montclair State University, Montclair, NJ, USACorrespondence: Ranjit Ranbhor, Business Development, Portfolio and Patents, Odin…

Also available at: DOAJ

Successful and Risk-Minimizing Treatment of Ulcerative Colitis by Positive Switch from JAK Inhibitors to Ustekinumab

Otake H; Matsumoto S; Mashima H

Biologics: Targets & Therapy, Vol. Volume 20 No. Issue 1 · 2026 · English · DOAJ Scopus

Haruka Otake, Satohiro Matsumoto, Hirosato Mashima Department of Gastroenterology, Jichi Medical University Saitama Medical Center, Saitama, JapanCorrespondence: Haruka Otake, Department of Gastroenterology, Jichi Medical University Saitama Medical Center, 1-847 Amanuma, Saitama, Omiya, 330-8503…

First-Line Serplulimab versus Other Anti-PD-1/PD-L1 Antibodies Plus Chemotherapy for Esophageal Squamous Cell Carcinoma: A Systematic Review with Benefit-Risk Assessment via Matching-Adjusted Indirect Comparison

Zhu Y; Qi X; Ni S et al.

Biologics: Targets & Therapy, Vol. Volume 20 No. Issue 1 · 2026 · English · DOAJ Scopus

Yi Zhu, Xiao Qi, Senmiao Ni, Wenting Qiu, Mengkai Chen Department of Biostatistics, Shanghai Henlius Biotech, Inc., Shanghai, People’s Republic of ChinaCorrespondence: Mengkai Chen, Department of Biostatistics, Shanghai Henlius Biotech, Inc., 188 Yizhou Road, Shanghai, 200233, People’s Republic of…

Late-Onset Ocular Myasthenia Gravis–Like Symptoms During Erenumab Therapy for Chronic Migraine: A Case Report

Qaqish A; Al Anber A; Abdelhafez G

Biologics: Targets & Therapy, Vol. Volume 20 No. Issue 1 · 2026 · English · DOAJ Scopus

Arwa Qaqish,1 Arwa Al Anber,2 Ghada Abdelhafez3 1Department of Biology and Biotechnology, Faculty of Science, the Hashemite University, Zarqa, 13133, Jordan; 2Department of Pharmacology and Public Health, Faculty of Medicine, the Hashemite University, Zarqa, 13133, Jordan; 3Department of…

Network Pharmacology-Based Exploration: Non-Targeted Metabolites of Lactobacillus-Fermented Chaenomeles speciosa (Sweet) Nakai, Smilax glabra Roxb. and Pueraria montana var. Lobata in Uric Acid Metabolism Intervention

Tan W; Li Z

Biologics: Targets & Therapy, Vol. Volume 20 No. Issue 1 · 2026 · English · DOAJ Scopus

Wei Tan, Zongjun Li College of Food Science and Technology, Hunan Agricultural University, Changsha, Hunan, People’s Republic of ChinaCorrespondence: Zongjun Li, Email hnlizongjun@163.comBackground: Previous studies have demonstrated that numerous medicine and food homology (MFH) possess the…

Apatinib Plus PD-1 Blockade versus Chemotherapy After Prior Immunotherapy in Advanced Gastric or Gastroesophageal Junction Adenocarcinoma: A Retrospective Cohort Study

Li RX; Yang HW; Zhang YF et al.

Biologics: Targets & Therapy, Vol. Volume 20 No. Issue 1 · 2026 · English · DOAJ Scopus

Rui-Xin Li, Hong-Wei Yang, Yun-Fei Zhang, Xin-Yu LiuDepartment of gastrointestinal surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, People’s Republic of ChinaCorrespondence: Xin-Yu Liu, Department of gastrointestinal surgery, The First Affiliated Hospital of…

Immunological Biomarkers in Glioblastoma: Targeting T and NK Cells for Enhanced Diagnosis and Prognosis

Akbari AM; Bourbour S; Seyedmehdi MS et al.

Biologics: Targets & Therapy, Vol. Volume 20 No. Issue 1 · 2026 · English · DOAJ Scopus

Amir Mohammad Akbari,1 Shahriyar Bourbour,1 Maryam Sadat Seyedmehdi,1 Sara Shiari,2 Auob Rustamzadeh,3,4 Farhad Seif,5 Shirin Farivar1 1Department of Cell and Molecular Biology, Faculty of Life Sciences and Biotechnology, Shahid Beheshti University, Tehran, Iran; 2School of Medicine, Shahid…

Vunakizumab for IL-17A–Mediated Diseases: A Review in Psoriasis and Spondyloarthritis

Yan H; Chen Y; Song Y et al.

Biologics: Targets & Therapy, Vol. Volume 20 No. Issue 1 · 2026 · English · DOAJ Scopus

Hongzhuo Yan,1,2,* Yu Chen,3,* Yali Song,1 Min Yan,1 Kexiang Yan1 1Dermatology Diagnosis and Treatment Center, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 2Shanghai University of Medicine & Health Sciences, Shanghai…

Bovine Milk Exosomes as Natural Cytoprotective Nanoplatforms Against Lead-Induced Toxicity

Panda S; Ahmad F

Biologics: Targets & Therapy, Vol. Volume 20 No. Issue 1 · 2026 · English · DOAJ Scopus

Subhrajita Panda, Faraz AhmadDepartment of Integrative Biology, School of Bio Sciences and Technology (SBST), Vellore Institute of Technology (VIT), Vellore, TN, 632014, IndiaCorrespondence: Faraz Ahmad, Department of Integrative Biology, School of Bio Sciences and Technology (SBST), Vellore…

Oral Acitretin Combined with Topical 0.1% Tretinoin Cream for Facial Basal Cell Carcinoma in an Elderly Patient: A Case Report

Shu Z; Jiang Y; Deng S et al.

Biologics: Targets & Therapy, Vol. Volume 20 No. Issue 1 · 2026 · English · DOAJ Scopus

Zhirong Shu,1,2,* Yu Jiang,1,2,* Shilin Deng,1,2 Tingnan Chen,1,2 Jingyao Liang,1,2 Xibao Zhang1,21Institute of Dermatology, Guangzhou Medical University, Guangzhou, 510095, People’s Republic of China; 2Department of Dermatology, Guangzhou Dermatology Hospital, Guangzhou, 510095, People’s…

Hemophagocytic Lymphohistiocytosis Triggered by HSV‑1 in a Patient with Refractory Crohn’s Disease After Long‑Term Sequential Immunosuppressive Therapy

Yao L; Tu H; Cao Q

Biologics: Targets & Therapy, Vol. Volume 20 No. Issue 1 · 2026 · English · DOAJ Scopus

Lingya Yao,1,2,* Hanxiao Tu,1,2,* Qian Cao1,21Department of Gastroenterology, Sir Run Run Shaw Hospital, College of Medicine Zhejiang University, Hangzhou, People’s Republic of China; 2Inflammatory Bowel Disease Center, Sir Run Run Shaw Hospital, College of Medicine Zhejiang University…

Safety Profile of Tozorakimab (an Anti-IL-33 Monoclonal Antibody): Data from the FRONTIER Phase 2 Program

Patel R; Brooks D; Gorseth E et al.

Biologics: Targets & Therapy, Vol. Volume 20 No. Issue 1 · 2026 · English · DOAJ Scopus

Rajesh Patel,1 Dennis Brooks,2 Elise Gorseth,2 Rachel Moate,3 Alexis Hofherr,4 Chris Kell,5 Gabriela Luporini Saraiva,6 Hitesh Pandya,1 Martin Jenkins,3 Ioannis Psallidas71Clinical Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK; 2Patient Safety…

Vunakizumab and Acitretin for Elderly Refractory Generalized Pustular Psoriasis: A Case Report and Comprehensive Literature Review

Deng S; Jiang Y; Li W et al.

Biologics: Targets & Therapy, Vol. Volume 20 No. Issue 1 · 2026 · English · DOAJ Scopus

Shilin Deng,1,2 Yu Jiang,1,2 Wei Li,1,2 Zhirong Shu,1,2 Tingnan Chen,1,2 Jingyao Liang,1,2 Xibao Zhang1,2 1Institute of Dermatology, Guangzhou Medical University, Guangzhou, 510095, People’s Republic of China; 2Department of Dermatology, Guangzhou Dermatology Hospital, Guangzhou, 510095, People’s…

Rapid Resolution of Psoriasis Following Low-Dose Interleukin-2 Monotherapy: A Case Report

Ma D; Li Z

Biologics: Targets & Therapy, Vol. Volume 20 No. Issue 1 · 2026 · English · DOAJ Scopus

Doudou Ma,1,2 Zhanguo Li1 1Department of Rheumatology and Immunology, Peking University People’s Hospital, Beijing, People’s Republic of China; 2Department of Rheumatology and Immunology, Peking University Shougang Hospital, Beijing, People’s Republic of ChinaCorrespondence: Zhanguo Li, Department…

Enhancement of Gastric Mucosal Defense by Phytomedicine in the Context of H. pylori–Associated Ulcer Disease

Paulraj RS; Perumal P; Ramachandran A et al.

Biologics: Targets & Therapy, Vol. Volume 20 No. Issue 1 · 2026 · English · DOAJ Scopus

Raja Singh Paulraj,1 Parthasarathi Perumal,2 Arunkumar Ramachandran,3 Anbazhagan Sathiyaseelan4 1Robert C. Byrd Biotechnology Science Center, Marshall University, Huntington, WV, USA; 2Department of Molecular and Cell Biology, Greensmed Labs, Chennai, TN, India; 3Multidisciplinary Research Unit, a…

Rheumatoid Factor Beyond Rheumatoid Arthritis: A Potential Marker of Cardiometabolic and Hepatic Risk

Egba SI; Orhonigbe IO; Achi NK et al.

Biologics: Targets & Therapy, Vol. Volume 20 No. Issue 1 · 2026 · English · DOAJ Scopus

Simeon Ikechukwu Egba,1,2 Innocent Ogheneovo Orhonigbe,3 Ngozi Kalu Achi,2 Gavin Chibundu Ikechukwu,2 Charles Nnanna Chukwu,2 Chukwudi Humphrey Omeoga4 1Department of Biochemistry, Kampala International University, Kampala, Uganda; 2Department of Biochemistry, Michael Okpara University of…

Optimization of Recombinant Human Interferon-Gamma Expression and Purification in E. coli, and Developing an Immunization Protocol for the Production of Optimal Humoral Response

Uwituze V; Mugasa CM; Namayanja M et al.

Biologics: Targets & Therapy, Vol. Volume 20 No. Issue 1 · 2026 · English · DOAJ Scopus

Vanessa Uwituze,1,2 Claire M Mugasa,2 Monica Namayanja,2 David Paul Nalumenya,2 Jerome Ndayisenga,3 Kenneth Ssekatawa,4 Charles Drago Kato2 1Department of Medical Laboratory Science, Mount Kigali University, Kigali, Rwanda; 2Department of Biotechnical and Diagnostic Sciences, Makerere University…

Anifrolumab in Refractory Oral Manifestations in Systemic Lupus Erythematosus: A Case Report and Literature Review

Garmish O; Smiyan S; Komorovsky R et al.

Biologics: Targets & Therapy, Vol. Volume 20 No. Issue 1 · 2026 · English · DOAJ Scopus

Olena Garmish,1,* Svitlana Smiyan,2,* Roman Komorovsky,2 Ivan Bilozetskyi3 1King’s College Hospital London, Dubai, United Arab Emirates; 2Department of Internal Medicine II, Ivan Horbachevsky Ternopil National Medical University, Ternopil, Ukraine; 3Clinic of Facial Aesthetics and Surgery…

Safety and Efficacy of Mesenchymal Stem Cell Therapy in Multiple System Atrophy: Systematic Review

Elimam N; Albarari SS; Shaalan Y et al.

Biologics: Targets & Therapy, Vol. Volume 20 No. Issue 1 · 2026 · English · DOAJ Scopus

Noon Elimam,1 Shams Samih Albarari,2 Yara Shaalan,3 Shazaa Mahmoud Elsheikh,4 Ainaa A Alzamari,5 Nourhan Elmekkawi,6 Rahaf Mogahed,7 Razan H Alghuweiri8 1Department of Neurology, Faculty of Medicine, Bogomolets National Medical University, Kyiv, Ukraine; 2Department of Neurology, Faculty of…