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Clinical Medicine Insights: Endocrinology and Diabetes
Scopus
ISSN 1179-5514 · SAGE Publishing · 353 artikel di indeks
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Artikel Jurnal
Euthyroid Sick Syndrome Precipitated By Rapid Weight Loss Following Semaglutide Initiation: A Case Report
Euthyroid sick syndrome (ESS) is characterized by abnormal thyroid function tests, most notably a low triiodothyronine (T3) level, occurring in the absence of intrinsic thyroid disease. A 54-year-old woman presented to the endocrinology clinic with a 4-month history of progressive fatigue…
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Artikel Jurnal
Frequency and Impact of Thyroid Hormone Abnormalities in COVID-19: An Observational Study at the Peak of the Pandemic
Background: COVID-19, caused by SARS-CoV-2, affects multiple organ systems, including the thyroid gland. Non-Thyroidal Illness Syndrome (NTIS) is frequently observed in severe systemic disease. NTIS-like thyroid hormone alterations have previously been reported in COVID-19. However, the…
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Artikel Jurnal
XLH Matters 2024 GCC Edition: Insights and Recommendations to Improve Outcomes for People Living With XLH in the Gulf Region
The XLH Matters 2024 GCC Edition meeting convened 51 physicians from 6 Gulf countries to discuss the diagnosis and management of patients with X-linked hypophosphatemia (XLH). This was the first XLH Matters meeting held in the Gulf Cooperation Council (GCC) region, reflecting the unique healthcare…
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Artikel Jurnal
The Relationship Between the Polymorphisms of RANK Gene and Type 2 Diabetes Mellitus in Postmenopausal Women
Background Studies have indicated an association between the receptor activator of nuclear factor-κB (RANK) gene and the pathogenesis of type 2 diabetes mellitus (T2DM). This study aimed to investigate the relationship between the polymorphisms at the RANK gene loci (rs3018362 and rs78326403) and…
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Artikel Jurnal
Translating CGM Regulatory Performance Metrics Into Clinical Interpretation: An Exploratory Expert Consensus Framework
Background Continuous glucose monitoring (CGM) performance is characterized by technical metrics that are inconsistently standardized across regulatory frameworks and variably connected to clinically meaningful outcomes, complicating interpretation and cross-device comparison. Objectives To develop…
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Artikel Jurnal
Efficacy and Safety of an Insulin Patch Pump Compared to Multiple Daily Injections in Pediatric Patients With Diabetes: A Randomized, Open-Label, Crossover, Non-Inferiority Clinical Trial
Background Insulin patch pumps offer advantages over multiple daily injections (MDI) for pediatric diabetes, but randomized trial evidence in Chinese children remains limited. Objectives To evaluate the efficacy and safety of a tubeless insulin patch pump (Equil™) compared with MDI in children and…
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Artikel Jurnal
Durable Insulin-free Remission in A−β+ Ketosis-Prone Diabetes With SGLT2 Inhibition: A Case Report With Longitudinal C-Peptide and CGM Data
Ketosis-prone diabetes (KPD) is a heterogeneous diabetes phenotype in which some patients with preserved β-cell function can achieve insulin independence after diabetic ketoacidosis (DKA). The role of sodium-glucose cotransporter 2 (SGLT2) inhibitors in maintaining remission in A−β+ KPD remains…
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Artikel Jurnal
Type 2 Diabetes and Hemodialysis: Metabolic Challenges and the Role of Intradialytic Exercise
Background and Aims Type 2 diabetes mellitus (T2DM) is the leading global cause of end-stage kidney disease (ESRD). Patients receiving hemodialysis often have a high cardiometabolic risk profile, including insulin resistance, glycemic variability, chronic inflammation, sarcopenia, and altered…
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Artikel Jurnal
Real-World Evidence of the GLP-1RA/SGLT2-i Therapy versus Standard Care: A Retrospective Cohort Study
Background Glucagon-like peptide-1 receptor agonists (GLP-1RA) and Sodium-glucose cotransporter-2 inhibitors (SGLT2-i) are effective antidiabetic therapies in patients with type 2 diabetes mellitus (T2DM). However, real-world evidence regarding the combined effectiveness and safety of these agents…
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Artikel Jurnal
Effects of Time-Restricted Eating on Insulin Sensitivity, Glycemic Control, and Metabolic Outcomes in Low- and Middle-Income Countries: A Systematic Review
Background Metabolic disease is accelerating across Low- and Middle-Income Countries (LMICs), where calorie-focused dietary prescriptions frequently fail due to cost and complexity. Time-Restricted Eating (TRE) is a distinct approach. It restructures when food is eaten rather than what or how much…
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Artikel Jurnal
Feasibility and Short-Term Outcomes of Radiofrequency Ablation for Low-Risk Papillary Thyroid Carcinoma in an Outpatient Endocrinology Setting in the USA
Background Radiofrequency ablation (RFA) has emerged as a minimally invasive alternative to surgery for selected patients with papillary thyroid carcinoma (PTC). However, North American data on outpatient endocrinologist performed RFA for PTC remains limited. This study evaluated the efficacy and…
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Artikel Jurnal
Changes in Glomerular Filtration Rate in Transgender Individuals Receiving Hormone Therapy: A Longitudinal Study
Background The changes that occur over time in the estimated glomerular filtration rate (eGFR) of transgender individuals receiving hormone therapy, and the factors that influence these changes, have not yet been fully evaluated. Methods This is a longitudinal study based on a retrospective cohort…
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Artikel Jurnal
Numerical and Clinical Accuracy of the FreeStyle Libre 2 System: A Diagnostic Accuracy Study in Critically Ill Patients
Background The accuracy of the FreeStyle Libre 2 system in critically ill patients needing insulin therapy remains inadequately evaluated. Objective To evaluate the clinical and numerical accuracy of continuous glucose monitoring (FreeStyle Libre 2) and capillary glucometry (StatStrip) compared…
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Artikel Jurnal
Treatment-Refractory Hypothyroidism due to Proteinuria During Combined Immune Checkpoint and Tyrosine Kinase Inhibitor Therapy – A Case Report
Immune checkpoint inhibitors (ICIs) are increasingly used in oncology and commonly cause thyroid dysfunction. Most patients who develop hypothyroidism after ICI-induced thyroiditis respond to standard weight-based levothyroxine replacement. However, causes of treatment-refractory hypothyroidism are…
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Artikel Jurnal
Effectiveness and Safety of the MiniMed 780G Advanced Hybrid Closed-Loop System in Older Adults With Type 1 Diabetes: A Comparative Cohort Study
Objective Evidence on advanced hybrid closed-loop (AHCL) systems in older adults with type 1 diabetes (T1D) remains limited. This study compared the effectiveness and safety of the MiniMed 780G system between adults aged ≥60 years and younger adults. Methods We conducted a cross-sectional study in…
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Artikel Jurnal
Secondary Adrenocortical Insufficiency in Liver Cancer Patient After Treatment With Cadonilimab: A Case Report
Immune checkpoint inhibitors (ICIs) offer important clinical benefits in antitumor therapy. However, they may cause potential and unpredictable immune-related adverse events (irAEs) due to the non-specific immunity activation. Although adrenocortical insufficiency (AI) is a rare irAE, rapid…
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Artikel Jurnal
Predictors and Mortality Determinants of Non-Thyroidal Illness Syndrome Among Patients in the Medical Intensive Care Unit in Northeastern Tanzania
Background Non-thyroidal illness syndrome (NTIS) frequently occurs in critically ill patients and reflects alterations in thyroid hormone metabolism without intrinsic thyroid disease. It has been increasingly recognized as a potential marker of disease severity and poor outcomes in intensive care…
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Artikel Jurnal
Virtual vs. In-Person Training for MinMed™ 780G Initiation: Comparable Effectiveness and Safety in Adults with Type 1 Diabetes
Background A knowledge gap persists regarding whether virtual training differs from in-person training in terms of metabolic control and clinical safety among adults with type 1 diabetes mellitus (T1D) initiating the MiniMed™ 780G advanced hybrid closed-loop (AHCL) system. Methods Observational…
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Artikel Jurnal
Atypical Hypoglycemia-Induced Stroke Mimic: A Case Report and Literature Review
This case describes an uncommon presentation of a hypoglycemia-related stroke mimic in a patient with poorly controlled type 2 diabetes, in whom acute neurological symptoms developed despite a blood glucose level above the conventional hypoglycemic threshold. A 72-year-old woman presented with…