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Genetics Selection Evolution
Scopus
ISSN 1297-9686 · BMC · 3.398 artikel di indeks
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Artikel Jurnal
Spatial modelling improves genomic evaluation in Tanzanian smallholder admixed dairy cattle
Abstract Background Smallholder dairy production systems in low-and middle-income countries are characterised by large phenotypic variance due to diverse environmental effects, farming practices, and crossbreeding. Furthermore, small herds, low genetic connectedness, and limited data recording…
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Artikel Jurnal
A comprehensive genome-wide scan for parent-of-origin expressed genes in the pig clarifies the conservation landscape of genomic imprinting
Abstract Background Genomic imprinting, a mechanism resulting in parent-of-origin expression of genes through epigenetic regulation, intersects with a broad range of biological fields, including evolution, molecular genetics and epigenetics, and determinism of complex traits. Although next…
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Artikel Jurnal
Across-breed analyses of genome-wide association studies for stature and mammary gland morphology in cattle reveal pleiotropic effects of the Friesian POLLED haplotype
Abstract Background Genome-wide association studies (GWAS) in cattle populations have traditionally relied on progeny-derived phenotypes such as estimated breeding values as input phenotypes to identify additive quantitative trait loci (QTL) for complex traits. Increasing availability of cow…
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Artikel Jurnal
Pangenome-based association testing between a structural variant located upstream of the KIT gene and head depigmentation across a diverse panel of cattle breeds
Abstract Coat color variation is a key phenotypic trait in domestic animals. Among the genetic factors involved, the KIT gene has frequently been associated with pigmentation diversity across species. In cattle, spotting or piebald phenotypes have been linked to variation in the genomic region…
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Artikel Jurnal
Genomic information increases prediction accuracy of behavior traits of Labrador Retrievers used as guide dogs
Abstract Background This study aimed to evaluate the accuracy of prediction of breeding values in a genomic selection program for behavior traits in a population of Labrador Retrievers used as guide dogs. Implementing genomic selection as a new tool in service dogs has the potential to increase…
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Artikel Jurnal
Genetic architecture of backfat thickness in laying hens: implications for extended egg production
Abstract Background To extend the egg production period of laying hens, it is important to understand the energy trade-offs during the late laying period (after 80 weeks of age) to avoid decreasing egg production or compromising health through inadequate body reserves. Although egg production is…
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Artikel Jurnal
A modified indirect method for computing inbreeding coefficients
Abstract The performance of existing methods for computing inbreeding coefficients—including tabular-based methods, Cholesky decomposition-based methods, and indirect methods—has been limited by either memory usage, pedigree depth, or average half-sib family size. In this note, we present a…
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Artikel Jurnal
Blood lipidome profiling reveals potential biomarkers linked to health and carcass quality traits in pigs
Abstract Background The modulation, activation, and differentiation of several immune cells is highly dependent on lipid metabolism. The objective of this study was to analyse the genetic determinism of the porcine plasma lipidome and its association to the animal immune capacity and production…
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Artikel Jurnal
Genetic variation of hypoxia tolerance in farmed fish: a systematic review for selective breeding purposes
Abstract Background Accelerating climate change has intensified hypoxic events in aquatic ecosystems. In aquaculture, high stocking densities make farmed fish particularly vulnerable to these episodes, leading to negative economic repercussions. This has driven interest in selective breeding for…
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Artikel Jurnal
Strategies to improve on selection based on estimated breeding values
Abstract Background Selection of individuals based on their estimated breeding values (EBV) aims to maximize response to selection in the next generation under an additive model. However, when the aim does not only include short-term population-wide genetic gain but also genetic gain over multiple…
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Artikel Jurnal
Genetic analysis of iris pigmentation in Swiss pig breeds identifies a missense KITLG variant as a potential causal factor for pale and heterochromatic irises
Abstract Background Iris pigmentation is a heritable trait with a complex genetic architecture. While the genetic basis of iris pigmentation has been extensively studied in humans, little is known about iris pigmentation in pigs. Iris pigmentation in pigs varies from different shades of brown or…
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Artikel Jurnal
Application of optimal contribution selection, trait distribution management, and group selection in layer chickens
Abstract Background Optimal Contribution Selection (OCS) aims at maximizing long term response to selection by balancing short term genetic gain and inbreeding rate. In this study, OCS, trait management, and group mating methods were applied to poultry data to evaluate their potential impact. Real…
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Artikel Jurnal
Genomic analysis of the inbreeding load for body weight, carcass and reproductive traits in the Rubia Gallega beef cattle population
Abstract Background Inbreeding, resulting from mating between relatives, leads to inbreeding depression, which can be traced back to hidden ancestral inbreeding loads. These loads exhibit variability and act as additive genetic effects that are only expressed in the inbred offspring. The objective…
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Artikel Jurnal
Genomic estimates of Identity-By-Descent relationships in large scale data sets
Abstract Background Genomic relationship and inbreeding estimates are either based on genetic drift (e.g. the Genomic Relationship Matrix; GRM), homozygosity (e.g. Runs of Homozygosity; ROH), or Identity-By-Descent (IBD). A genomic IBD-based relationship matrix, G la , is obtained by linkage…
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Artikel Jurnal
Investigating the genetic basis of susceptibility to amoebic gill disease and idiopathic gill lesions in Atlantic salmon populations using field data
Abstract Background Gill-related morbidity and mortality have become a major concern to the Atlantic salmon industry worldwide. Understanding the genetic mechanisms underlying susceptibility to gill diseases or lesions can help guide mitigation efforts. Genome-wide association analysis was…
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Artikel Jurnal
ReaGP: integrating residual units and attention mechanisms in convolution neural network for genomic prediction
Abstract Background Various methods have been widely utilized to estimate the genomic breeding values (GEBVs) for genomic prediction. Traditional approaches often relied on the assumption of linear regression models, which struggle to effectively capture the nonlinear relationships between limited…
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Artikel Jurnal
Genetic diversity and population structure of U.S. Suffolk sheep participating in the national sheep improvement program
Abstract Background The Suffolk is the primary terminal sire breed in the U.S. As a breed that participates in the National Sheep Improvement Program (NSIP), Suffolk breeders are attempting to accumulate enough genomic information to provide genomic-enhanced estimated breeding values as part of the…
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Artikel Jurnal
Integrative analysis of GWAS, Bayesian fine-mapping, Mendelian randomization and colocalization reveals genetic determinants underlying milk-related traits in dairy cattle
Abstract Background Genome-wide association studies (GWAS) has identified many genetic variants associated with milk-related traits in dairy cattle. However, the causal variants or genes remain largely unknown. In this study, using a large population (> 10,000 individuals) of Chinese Holstein…
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Artikel Jurnal
GWAS on early sexual maturation across freshwater and seawater environments in domesticated Lochy strain of Atlantic salmon
Abstract Background Early sexual maturation is a challenging obstacle to overcome in Atlantic salmon farming. This trait primarily affects males and occurs in both freshwater fish farms and sea culture cages during the fattening phase. Current strategies for preventing early maturation include a…
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Artikel Jurnal
Genomic selection strategies to overcome genotype by environment interactions in biosecurity-based aquaculture breeding programs
Abstract Background Family-based selective breeding programs typically employ both between-family and within-family selection in aquaculture. However, these programs may exhibit a reduced genetic gain in the presence of a genotype by environment interactions (G × E) when employing biosecurity-based…
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