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Gynecology Obstetrics & Reproductive Medicine
ISSN 1300-4751 · Medical Network · 919 artikel di indeks
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Artikel Jurnal
Anemia and Postpartum Depression: The Role of Anemia Phenotype
Objective: To evaluate the relationship between anemia and postpartum depressive symptoms in term pregnant women and to examine whether different anemia phenotypes and hematological parameters are associated with postpartum depressive symptoms. Study Design: This retrospective observational study…
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Artikel Jurnal
In Search for an Effective Conservative Surgery for Diffuse Adenomyosis in a Resource-Constrained Setting: Outcome of Open Double-Flap Adenomyomectomy in Infertile Women
OBJECTIVES: Adenomyosis is a common cause of pelvic pain, menorrhagia, and infertility in women of reproductive age. There remains a need for an effective fertility-sparing surgical option for managing diffuse adenomyosis. This study evaluated the clinical and reproductive outcomes of open…
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Artikel Jurnal
Perinatal and Neonatal Outcomes of Grand Multiparous Refugee Women Under the Age of Thirty-Five: A Comparative Study
OBJECTIVES: To compare maternal and neonatal outcomes between grand multiparous Syrian refugee women younger than 35 years and Türkiye citizens. STUDY DESIGN: In this retrospective cohort study we screened electronic birth records according to predefined eligibility criteria. Of 313 potentially…
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Artikel Jurnal
Cigarette Smoking Disrupts Sperm Nuclear Maturation, Epigenetic Regulation, and CatSper-Mediated Calcium Signaling
OBJECTIVE: The CatSper (cation channel of sperm) channel is the principal pH-sensitive and low-voltage-activated cation channel that regulates Ca²⁺ influx required for sperm hyperactivation. Exposure to cigarette smoke is known to affect semen parameters and sperm DNA integrity adversely. This…
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Postoperative Arterial Thromboembolism Causing Acute Limb Ischemia and Amputation Following Gynecologic Oncology Malignancy Surgery: Presentation of Two Cases
This case report presents two rare cases and aims to highlight arterial thromboembolism (ATE) as a rare but potentially devastating complication following gynecologic oncology surgery. Chronic kidney disease (CKD) has been demonstrated to heighten susceptibility to thrombotic events through a…
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Artikel Jurnal
Clinical and Reproductive Outcomes After Hysteroscopic Repair of Isthmocele
OBJECTIVE: The growing global prevalence of cesarean delivery has increased the incidence of long-term scar complications, among which isthmocele represents a clinically relevant yet often under-recognized entity. This defect, characterized by incomplete myometrial healing at the cesarean incision…
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Systemic Thiol-Disulfide Homeostasis and Contemporaneous Menstrual Pain Intensity in Primary Dysmenorrhea: A Prospective Observational Study
OBJECTIVE: Primary dysmenorrhea (PD) is associated with prostaglandin-mediated uterine hypercontractility, transient ischemia, inflammation, and oxidative stress. Whether systemic redox biomarkers reflect menstrual pain intensity at a specific clinical time point remains uncertain. This study…
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Embryo Ploidy and Ovarian Response in Gonadotropin-Releasing Hormone Antagonist Versus Progestin-Primed Ovarian Stimulation Protocols with Recombinant Luteinizing Hormone: A Within-Patient Study
OBJECTIVE: To compare embryo ploidy rates and ovarian response outcomes between gonadotropin-releasing hormone (GnRH) antagonist and progestin-primed ovarian stimulation (PPOS) cycles with recombinant luteinizing hormone (rLH) administered from stimulation onset. STUDY DESIGN: This retrospective…
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Longitudinal Assessment of Fetal Ductus Arteriosus Morphometry: Establishing Gestational Age-Specific Reference Values
OBJECTIVES: To longitudinally evaluate fetal ductus arteriosus (DA) morphometric changes and establish normative reference values between 18 and 36 weeks of gestation. STUDY DESIGN: This prospective cohort study included 29 pregnant women with structurally normal singleton fetuses and confirmed…
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Artikel Jurnal
Development of Gestational Age-Specific Nomograms for Fetal Splenic Artery Doppler Parameters Between 18 and 40 Weeks of Gestation
OBJECTIVE: To characterize the gestational age-related behavior of fetal splenic artery (SA) Doppler parameters and to establish appropriate reference models for the systolic/diastolic (S/D) ratio, pulsatility index (PI), peak systolic velocity (PSV), and time-averaged maximum velocity (TAMV) in…
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Artikel Jurnal
Evidence-Based Clinical Recommendations For The Use Of Antenatal Corticosteroids
Antenatal corticosteroid (ACS) therapy is one of the most effective evidence-based interventions for improving neonatal survival and reducing major short-term morbidities associated with prematurity in pregnancies at risk of preterm birth. However, the clinical benefit of ACS largely depends on…
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Utilizing the Prognostic Nutritional Index to Predict Chemotherapy Toxicities in Ovarian Cancer Patients: Long-Term Tertiary Center Experiences
Objective: Our aim was to clearly evaluate the Prognostic Nutritional Index's ability to predict chemotherapy-induced toxicity in ovarian cancer patients undergoing platinum-based chemotherapy. Study Design: This retrospective cohort study of 158 patients with epithelial ovarian cancer treated with…
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Artikel Jurnal
Fumarate Hydratase-Deficient Leiomyomas: A Retrospective Case Series with Clinical and Familial Findings Suggestive of Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome
OBJECTIVES: Fumarate hydratase (FH)-deficient uterine leiomyomas are a rare variant of smooth muscle tumors that may signal underlying hereditary syndromes like HLRCC, making their recognition crucial for gynecologists and pathologists. STUDY DESIGN: This retrospective case series included ten…
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Artikel Jurnal
Urethral Resection and Neo-Urethra in Invasive Vulvar Cancer
Vulvar cancer is a significant gynecological malignancy. It often invades surrounding organs at the time of diagnosis. In cases of urethral invasion, lack of effective reconstruction may result in serious micturition disorders. We performed a urethral resection (surgical removal of part of the…
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Artikel Jurnal
Intrahepatic Cholestasis of Pregnancy: A Narrative Review
This narrative review synthesizes the current literature on the pathogenesis and management of Intrahepatic Cholestasis of Pregnancy (ICP). ICP is a multifactorial liver disorder characterized by intense pruritus and elevated serum bile acids (SBA) and/or liver enzyme levels, typically emerging in…
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Artikel Jurnal
Longitudinal Arterial and Venous Doppler Changes in Late-Onset Fetal Growth Restriction
OBJECTIVE: This study aimed to evaluate longitudinal changes in arterial and venous Doppler parameters in late-onset fetal growth restriction and to investigate their association with NICU admission. STUDY DESIGN: This prospective cohort study included singleton pregnancies diagnosed with LO-FGR at…
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Artikel Jurnal
Young Women and Burden of Unsafe Abortion: 2023 Estimates from Two Hospitals in Yaoundé, Cameroon
OBJECTIVES: Adolescent girls and young women (AGYW) are particularly vulnerable to unsafe abortion (UA). The study aimed to describe the distribution of women with complications of abortions, determine the frequency of complications and deaths, and estimate measures of disease burden in 2023 at two…
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APRI, FIB-4, and FIB-5 Scores and Their Association with Late-Onset Preeclampsia
OBJECTIVES: Late-onset preeclampsia (LO-PE) is a major cause of maternal–perinatal morbidity. Noninvasive liver fibrosis indices, the AST-to-platelet ratio index (APRI), Fibrosis-4 (FIB-4), and Fibrosis-5 (FIB-5), may capture subclinical hepatic injury in preeclampsia. We assessed the association…
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Artikel Jurnal
Hemogram-Derived Inflammatory and Oxidative Stress-Related Indices in Second-Trimester Pregnancy Loss
OBJECTIVES: To investigate hemogram-derived inflammatory indices in women with spontaneous second-trimester pregnancy loss and to compare these parameters with those of the women who achieved term delivery. STUDY DESIGN: This retrospective case–control study included women aged 18–35 years. There…
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Concordance of Colposcopy-Directed Biopsy and Conization Results in Cervical Dysplasia
OBJECTIVE: Cervical cancer prevention requires proper management of women with cervical intraepithelial neoplasia (CIN). A colposcopy is key to diagnosing CIN in women with abnormal cytology. Colposcopy identifies lesions, assesses grading, and guides biopsies. Excisional procedures like cold knife…