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Ankara Üniversitesi Tıp Fakültesi Mecmuası
ISSN 1307-5608 · Ankara University Press · 676 articles in the index
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Journal Article
Evaluation of the Diagnostic Performance of the Indirect Hemagglutination Test in the Differential Diagnosis of Cystic Echinococcosis: Single Center Experience
Objectives: The purpose of this study is to reveal the epidemiological data of cystic echinococcosis (CE) patients who applied to our hospital and to determine the diagnostic performance of the indirect hemagglutination test (IHAT). Materials and Methods: The patients whose serum samples were…
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Journal Article
Assessment of Psychosocial Risks and Mental Health Status in a Faculty of Dentistry
Objectives: It was aimed to evaluate the psychosocial risks, mental health status of the employees and related factors in a faculty of dentistry. Materials and Methods: In this cross-sectional study, no sample was selected. It is planned to include all employees at the faculty of dentistry between…
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Journal Article
Menopausal Status at Diagnosis is a Prognostic Indicator in Patients who are Operated for Uterine Carcinosarcoma
Objectives: Uterine carcinosarcoma is a rare type of uterine cancer, and due to its rarity, there is limited evidence for prognostic factors and treatment. The objective of this study is to assess the influence of histologic, clinical, and demographic characteristics on overall survival (OS) and…
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Journal Article
Anesthesia Management in a Rare Case: Wolf-Hirschhorn Syndrome
Wolf-Hirschhorn syndrome is a rare disease and may cause difficulties in airway management. In addition, intraoperative complications may occur. We will share with you our anesthesia management experience in a patient who is scheduled to undergo repair due to a cleft lip.
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Journal Article
In Vivo Effects of Exogenous BDNF Administration on AMPA Receptors in the Dentate Gyrus of Female Rats
Objectives: Previous in vitro studies have demonstrated that brain-derived neurotrophic factor (BDNF) modulates α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) expression and the trafficking of synaptic AMPA receptors (AMPARs). However, it is not known whether exogenous BDNF…
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Journal Article
The Anti-Proliferative Effect of Genistein on Antioxidant System, Cell Proliferation, and Apoptosis: Implications for Hormone-Refractory Prostate Cancer Therapy
Objectives: This study aims to examine the effect of different genistein concentrations on apoptosis, estrogen receptor beta, and manganese superoxide dismutase (MnSOD) protein expressions in PC3 hormone-resistant metastatic prostate cancer cell lines. Materials and Methods: Genistein…
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Journal Article
Evaluation of Academic Success of Ankara University Faculty of Medicine Students According to the Social Determinants of Health
Objectives: The objective of this study is to investigate the association between social determinants of health (SDOH) and academic success among preclinical students at Ankara University Faculty of Medicine. We aim to provide insights for policies and practices that promote student well-being and…
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Journal Article
Unusual Presentation of Type 3 Posterior Urethral Valve: A Case Report
Type 3 posterior urethral valves (PUV) are rare in pediatric urology departments and appear as a diaphragm with a central pinpoint opening in the urethra. A 14-year-old male patient presented with post-void hematuria and dribbling during micturition. Ultrasonography revealed no…
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Journal Article
A Real World Study: Efficacy and Safety of Pegylated Interferon Alpha-2a in Patients with Myeloproliferative Neoplasm
Objectives: Several clinical studies have reported promising results in patients with essential thrombocythemia (ET) and polycythemia vera (PV) treated with pegylated interferon alpha-2a (PEG-IFN-α-2a). In this study, we evaluated the efficacy and safety of PEG-IFN-α-2a in patients with…
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Journal Article
Comparative Assessment of Urological Emergency Cases Before and After the COVID-19 Outbreak
Objectives: Coronavirus disease-2019 (COVID-19) pandemic originated from China and has affected all countries in the world as well as Türkiye. In our study, we aimed to evaluate the effects of COVID-19 pandemic on urological emergency admissions. Materials and Methods: Urological emergency…
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Journal Article
Avascular Necrosis and Risk Factors in Kidney Transplant Recipients: A Single-Center Experience
Objectives: Renal osteodystrophy, osteoporosis, bone fractures, and avascular necrosis (AVN) are prevalent complications observed in the post-transplant period among kidney transplant recipients (KTRs). Despite notable advancements, AVN remains a significant and devastating complication following…
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Journal Article
Family-Centeredness of Special Education and Rehabilitation Services for Young Children with Special Needs in Türkiye
Objectives: This study aims to evaluate the family-centeredness of early childhood special education and rehabilitation services and assess families’ satisfaction with these services. Materials and Methods: This cross-sectional study included 3-36 months-old children with special needs and their…
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Journal Article
SARS-CoV-2 and Mycobacterium Fortuitum Coinfection: A Case Report
Coronavirus disease-2019 (COVID-19) pandemic caused millions of people to become infected and had resulted several deaths. After initial resolution, in cases of clinical deterioration, it is essential to consider the possibility of coinfections. Non-tuberculousmycobacteria infections are rare and…
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Journal Article
Malignancy Associated Aortitis in a Patient with Fever of Unknown Origin
Aortitis, characterized by inflammatory changes in the aortic wall, can present with various manifestations. It should be considered in the differential diagnosis of fever of unknown origin (FUO), especially in patients with aortic aneurysm. Accurate differentiation between infectious and…
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Journal Article
Hypoxia Induced Downregulation of Na+/H+ Exchanger-1 Activity Decreases Tumor Cell Proliferation
Objectives: Hypoxia and acidosis are the hallmarks of proliferative tumor microenvironment which can modulate the expression and function of Na+/H+ exchanger-1 (NHE1) via hypoxia inducible factor 1 (Hif). Here, we investigate the severity and time dependent effects of chronic hypoxia on NHE1…
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Journal Article
The Effect of Adjuvant Chemoradiotherapy Initiation Time on Prognosis in Glioblastoma Multiforme
Objectives: To determine survival and investigate associated prognostic factors in glioblastoma multiforme (GBM) patients receiving adjuvant therapy. Materials and Methods: The study population comprised patients with isocitrate dehydrogenase wild-type GBM who were enrolled between 1 September 2022…
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Journal Article
Evaluation of the Opinions and Anxiety Levels of Female Breast Cancer Patients Receiving Outpatient Chemotherapy Regarding Fertility
Objectives: As screening and treatment for breast cancer advance, an increasing number of young patients are confronting treatment-related infertility. The aim of this study was to analyze patients’ opinions on fertility, and to assess the impact of these opinions on their depression and anxiety…
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Journal Article
Evaluation of Retinal Layers by Optical Coherence Tomography in Patients with Acromegaly
Objectives: Acromegaly, a rare endocrine disorder caused primarily by growth hormone (GH) secreting pituitary adenomas, leads to elevated levels of growth GH and insulin-like growth factor 1 (IGF-1), resulting in systemic complications and ocular manifestations. These include increased corneal…
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Journal Article
Identification of Mitochondrial-Related Genes as Potential Biomarkers for Docetaxel-Resistant Prostate Cancer
Objectives: Prostate cancer (PC) is the most common cancer among men worldwide and a significant cause of cancer-related deaths. Docetaxel (DX), a taxane-based chemotherapeutic agent, was the first treatment to exhibit substantial efficacy in the management of PC. This study aims to demonstrate the…
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Journal Article
Surgical Outcomes of Carpal Tunnel Syndrome in Rheumatologic Patients
Objectives: Carpal tunnel syndrome (CTS) is a common condition that often coexists with rheumatologic diseases, leading to significant functional impairment and reduced quality of life. This study aimed to evaluate the outcomes of open decompression surgery for CTS in individuals with rheumatologic…