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The Saudi Journal of Gastroenterology
Scopus
ISSN 1319-3767 · Wolters Kluwer Medknow Publications · 1.587 artikel di indeks
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Artikel Jurnal
Effectiveness of AI-enhanced colonoscopy: A case-control study using real world evidence in a young screening age population
Background:Computer aided detection (CADe) colonoscopy has been shown in randomized controlled trials to improve detection of adenomatous colorectal polyps. However, in real-world settings the benefits are less clear. Our objective was to assess CADe colonoscopy compared to routine colonoscopy in a…
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Artikel Jurnal
Impact of 24-hour urine output trajectories on intra-abdominal hypertension risk in acute pancreatitis patients: Insights from MIMIC-IV database
Background:Intra-abdominal hypertension (IAH) is a common complication in patients with acute pancreatitis (AP), closely associated with reduced urine output. However, relationship between alterations in urine output and IAH in AP patients remains unclear. Methods:A retrospective study was…
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Artikel Jurnal
Metabolic dysfunction-associated steatotic liver disease management in Saudi Arabia: A modified Delphi-based adaptation of international standards
The reclassification of nonalcoholic fatty liver disease (NAFLD) to metabolic dysfunction-associated steatotic liver disease (MASLD) marks a significant shift in understanding liver disease, particularly in Saudi Arabia, where metabolic disorders are highly prevalent. This study aimed to develop…
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Artikel Jurnal
Eradication rates of Helicobacter pylori regimens and predictors of treatment failure: A multicenter real-world study in Saudi Arabia
Background:The increasing prevalence of Helicobacter pylori resistance to clarithromycin and other antibiotics has led to a decline in eradication rates globally. Limited multicenter data from Saudi Arabia exist regarding the comparative effectiveness of various eradication regimens and predictors…
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Artikel Jurnal
Paving the way for green endoscopy in Saudi Arabia: A call for sustainable gastroenterology practice
Green endoscopy, the integration of environmentally sustainable practices into gastrointestinal endoscopy services, is gaining global momentum amid rising concerns about healthcare’s carbon footprint. Endoscopy contributes significantly to greenhouse gas emissions, medical waste, and energy…
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Artikel Jurnal
Intermittent fasting and liver disease: Insights from the Ramadan model
Intermittent fasting (IF) has gained growing interest for its potential metabolic benefits. However, the unique physiological aspects of Ramadan fasting (RF), a culturally and religiously significant form of dry IF, remain underexplored, particularly regarding liver disease. RF imposes distinct…
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Artikel Jurnal
The global, regional, and national patterns of change in the burden of gastroesophageal reflux disease, 1990-2021: An analysis of the global burden of disease study 2021 and forecast to 2036
Background:Data from the Global Burden of Disease (GBD) 2019 indicate a growing global burden of gastroesophageal reflux disease (GERD), with significant variations across regions and socio-demographic index (SDI) levels. Ongoing monitoring is essential to inform prevention strategies…
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Artikel Jurnal
Trends in the burden and quality of care for upper gastrointestinal diseases from 1990 to 2021: An analysis of the global burden of disease study 2021
Background:Upper gastrointestinal (GI) diseases, primarily gastroesophageal reflux disease (GERD), peptic ulcer disease (PUD), and gastritis and duodenitis (GD), are highly prevalent, chronic, and recurrent conditions worldwide, imposing a substantial burden on population health and quality of…
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Artikel Jurnal
Effects of different drying temperatures and times on the drying efficiency in reprocessing of flexible endoscopes
Background: The drying process is a crucial step in the reprocessing of flexible endoscopes. However, the optimal drying time remains inconclusive, and the impact of temperature on drying efficiency is still unclear. This study aims to provide experimental data on the optimal parameters for…
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Artikel Jurnal
Saudi Gastroenterology Association (SGA) clinical care pathway and standards of care for peroral endoscopic myotomy (POEM) in achalasia
Peroral endoscopic myotomy (POEM) has become an established, minimally invasive therapy for achalasia, demonstrating high efficacy and safety across all disease subtypes. With its expanding adoption in Saudi Arabia, the Saudi Gastroenterology Association (SGA) developed a clinical care pathway and…
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Artikel Jurnal
Patterns and predictors of biologic therapy switching in inflammatory bowel disease at a tertiary care center: A retrospective observational study
Background: Approximately one-third of inflammatory bowel disease (IBD) patients fail to respond to anti-tumor necrosis factor (anti-TNF) therapy, presenting a significant challenge. The two management strategies are changing to a second anti-TNF agent or a drug with a different mechanism of…
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Artikel Jurnal
Cost calculation model of introducing Upadacitinib and Risankizumab for adult ulcerative colitis and Crohn’s disease in the Kingdom of Saudi Arabia
Background: Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn’s disease (CD), affects approximately 4.9 million individuals globally. Advanced therapies have significantly improved IBD management; however, maintenance doses commonly exceed labeled recommendations for…
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Artikel Jurnal
Frequency of thiopurine methyltransferase variants and exploratory predictors of azathioprine-induced leukopenia in Saudi patients with inflammatory bowel disease
Background: Azathioprine, a common inflammatory bowel disease (IBD) treatment, carries a myelosuppression risk, particularly leukopenia. Thiopurine methyltransferase (TPMT) genotyping can predict azathioprine-induced leukopenia (AIL), but data on TPMT polymorphisms in Saudi IBD patients are scarce…
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Artikel Jurnal
Effectiveness and safety of upadacitinib in refractory pediatric inflammatory bowel disease: A single-arm meta-analysis of observational studies
Background: Upadacitinib (UPA), a selective Janus kinase-1 (JAK-1) inhibitor, has been approved for adults with refractory inflammatory bowel disease (IBD). Its oral formulation and efficacy after biologic failures make it an attractive option for children with refractory IBD. We conducted a…
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Artikel Jurnal
Achalasia management with per-oral endoscopic myotomy: A study of clinical success and complications at a tertiary center in Saudi Arabia
Background: Per-oral endoscopic myotomy (POEM) has emerged as a minimally invasive treatment for achalasia, with growing global adoption. However, regional data from Saudi Arabia are scarce. This study aimed to evaluate the efficacy, safety, and long-term outcomes of POEM in a tertiary referral…
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