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Annals of Medicine
Scopus
ISSN 1365-2060 · Taylor & Francis Group · 3,543 articles in the index
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Journal Article
Variants in the interferon regulatory factor 5 gene confer genetic risk for systemic lupus erythematosus in a Han Chinese population
Background Interferon regulatory factor 5 (IRF5), integral to interferon signaling pathways, has been identified as a susceptibility locus for systemic lupus erythematosus (SLE). Nevertheless, the relationship between IRF5 variants and SLE risk within the Han Chinese demographic remains…
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Journal Article
Kinetics and prognostic value of heparin binding protein at the ST-segment-elevation myocardial infarction
Background This research aimed to explore the potential role of heparin-binding protein (HBP) as a prognostic biomarker for adverse events among individuals diagnosed with ST-segment elevation myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (pPCI).Methods This…
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Journal Article
Physical activity and general medical knowledge of adult residents of the silesian voivodeship
Background The aim of the study was to assess the relationship between the physical activity and medical knowledge of adult residents of the Silesian Voivodeship.Methods 1,638 (100%) adult residents of the Silesian Voivodeship were analyzed. The group was divided as follows: Group A - people not…
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Journal Article
Machine learning-based risk factors for acute-on-chronic liver failure in alcohol-associated liver disease
Background In patients with alcohol-associated liver disease (ALD), heavy and prolonged alcohol consumption can trigger acute-on-chronic liver failure (ACLF), a condition associated with high early mortality and significant clinical challenges. Early identification of patients at risk is critical…
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Journal Article
Extracorporeal therapies in the management of paraquat poisoning: a comprehensive review of current evidence
Introduction Paraquat (PQ) poisoning has a high mortality rate due to rapid systemic distribution and oxidative organ damage, particularly in the lungs. Conventional therapies are often inadequate, prompting interest in extracorporeal therapies to enhance PQ clearance.Methods This narrative review…
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Journal Article
Triglyceride-glucose index as a novel predictor of major adverse cardiovascular events in patients with coronary revascularization: a meta-analysis of cohort studies
Background The triglyceride-glucose index (TyG) has gained attention as an alternative indicator for assessing insulin resistance (IR). The purpose of this study was to comprehensively summarize the correlation between the TyG index and cardiovascular events in patients with coronary…
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Journal Article
Bacterial cell envelope components of gut commensals: effects in host-microbe interaction
The bacterial cell envelope is a complex structure composed of proteins, lipids, and other molecules that form the physical boundary between bacteria and the environment. In the gut microbiome, commensal bacteria play a fundamental role in maintaining intestinal homeostasis and modulating host…
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Journal Article
Regional homogeneity alterations reflect pain and emotional dysregulation in adenomyosis
Purpose Adenomyosis (AM) with dysmenorrhea (AMD) is a global public health concern that may involve abnormal brain function and heightened vulnerability to anxiety and depression. This study aimed to investigate static and dynamic regional homogeneity (sReHo and dReHo) alterations in AMD and their…
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Journal Article
Testicular ageing as a central hallmark of male senescence: characteristics, molecular mechanisms and emerging therapeutic strategies
Background The testis is a male-specific organ that plays a central role in spermatogenesis and androgen secretion. Testicular ageing is a hallmark of male senescence. However, the underlying mechanisms, as well as strategies to prevent, delay, or reverse this process, remain incompletely…
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Journal Article
Effects of nine sedative-analgesic combinations on fatigue after gastrointestinal endoscopy: a randomized controlled 3 × 3 factorial trial protocol
Introduction Post-procedural fatigue is common after sedated gastrointestinal endoscopy and prolongs recovery. We describe a protocol for a prospective, single-center, randomized, controlled, 3 × 3 factorial trial to evaluate the effects of different sedative–analgesic combinations on…
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Journal Article
Dexmedetomidine nasal spray for patients undergoing endoscopic retrograde cholangiopancreatography: protocol for a randomized controlled trial
Introduction Endoscopic retrograde cholangiopancreatography (ERCP) is associated with significant discomfort and necessitates adequate sedation. This study aims to determine the effect of dexmedetomidine nasal spray adjunct to propofol sedation for patients undergoing ERCP procedures.Patients and…
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Journal Article
Prevalence and incidence of post-intensive care syndrome among intensive care unit survivors: a systematic review and meta-analysis
Background Post-intensive care syndrome (PICS) is a post-discharge complication from the intensive care unit (ICU) that manifests as a range of physical, cognitive, and psychological impairments for patients. Given the growing number of ICU survivors and the vital role of this syndrome in…
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Journal Article
Baseline D-dimer as a predictor of immune checkpoint inhibitor efficacy in cancer
Background Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment by enhancing antitumor immunity, yet durable responses are observed in only a fraction of patients. Identifying accessible and reliable biomarkers to predict therapeutic efficacy remains a critical unmet need…
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Journal Article
A system-level metastable model of cancer evolution: integrating replication stress, cell cycle deregulation and chromosomal instability
Introduction Cancer cell proliferation occurs within the context of persistent genomic instability. In this review, we propose the RS–CCD–CIN axis as a systems-level framework in which replication stress (RS), cell cycle deregulation (CCD) and chromosomal instability (CIN) form an interdependent…
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Journal Article
Comparative effectiveness of percutaneous coronary intervention strategies for coronary small-vessel disease: a network meta-analysis of randomized trials
Background Coronary small-vessel disease (SVD) remains challenging for percutaneous coronary intervention (PCI) because small lumens magnify restenosis and ischemic risk. Multiple devices are available, yet their comparative performance is uncertain. This study evaluated and ranked PCI strategies…
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