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Ophthalmic Research, Pp 1-22 (2026)
Scopus
ISSN 1423-0259 · Karger Publishers · 69 artikel di indeks
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Artikel Jurnal
Construction and Applications of Knowledge Graphs in Ophthalmology
Knowledge Graph (KG) is an artificial intelligence technique that provides a structured representation of medical entities and their relationships, thereby facilitating integration of heterogeneous information, knowledge discovery, and intelligent reasoning. The process of KG construction includes…
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Artikel Jurnal
Correlations between Clinical Activity Score and Serological and Radiological Data in Treatment-naïve Ethnic Han Chinese Thyroid Eye Disease
Purpose: Clinical activity score (CAS) is widely used to assess thyroid eye disease (TED) activity, but its predictive value in East Asian patients remains unclear. This study evaluated correlation between CAS and both radiological and serological markers in treatment-naïve ethnic Han Chinese TED…
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Artikel Jurnal
The Link Between Obstructive Sleep Apnea and Dry Eye Disease: Pathophysiology and Current Updates
Obstructive Sleep Apnea (OSA) and Dry Eye Disease (DED) are increasingly recognized as interrelated conditions with significant clinical implications. Tear film stability is disrupted by inflammation and lacrimal and meibomian glands dysfunction, which are caused by intermittent hypoxia and…
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Impact of Diabetic Peripheral Neuropathy on Corneal Sensitivity and Ocular Surface
Introduction: Diabetes mellitus (DM) is frequently associated with microvascular complications, including diabetic peripheral neuropathy (DPN). The cornea, one of the most densely innervated tissues in the body, has been proposed as a surrogate marker for small fiber neuropathy. Patients with DM…
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Changes of Schlemm’s Canal and Trabecular Meshwork Dimensions from Digital Ocular Massage in High Myopia: A Pilot Study
Introduction: This study evaluated changes of Schlemm’s canal (SC) and trabecular meshwork (TM) dimensions from digital ocular massage in high myopia. Methods: Healthy participants with either high myopes (≤−6.00 D) or with refractive errors ≥ −3.00D were recruited. Right eyes underwent digital…
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Artikel Jurnal
Mechanisms and Safety of Therapeutic Strategies in Meibomian Gland Dysfunction: A Narrative Review
Background: Meibomian gland dysfunction (MGD) is a chronic and widespread abnormality of the meibomian glands that often results in symptoms such as eye irritation and blurred vision, significantly affecting patients’ daily activities. While conventional treatments like warm compresses and…
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Correlations between Spectral Domain Optical Coherence Tomography Measurements and Visual Acuity in Patients with Retinitis Pigmentosa at Baseline and One-Year Follow-Up
Introduction: This study aimed to investigate the relationship between spectral domain optical coherence tomography (SD-OCT) structural findings and visual acuity in patients with retinitis pigmentosa (RP), with and without cystoid macular edema (CME), at baseline and 1-year follow-up. Methods…
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Artikel Jurnal
Platelet-Derived Growth Factor Isoform Imbalance Is Associated with Innate Inflammation and Corneal Epitheliopathy in Dry Eye Disease
Introduction: Tear-deficient dry eye disease (DED), including Sjögren’s syndrome and ocular graft-versus-host disease (oGVHD), is often refractory to therapy. We tested whether platelet-derived growth factor (PDGF) isoform imbalance, quantified as a PDGF-AB/BB: PDGF-AA ratio (“PDGF Ratio”), is…
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Ab Externo Continuous Pressure Technique for Descemet Membrane Endothelial Keratoplasty in Vitrectomized Eyes
Introduction: Descemet membrane endothelial keratoplasty (DMEK) in vitrectomized eyes presents a significant surgical challenge, as the compromised counter-pressure of the iris-lens diaphragm impedes proper shallowing of the chamber, making graft unfolding and centration challenging. To address…
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Artikel Jurnal
Microbial Keratitis in Southern Arizona
Introduction: There is a paucity of data on microbial keratitis in the southwestern USA, specifically southern Arizona. Understanding demographic factors and causative organisms will help design future treatments and preventative measures. Methods: A retrospective chart review was conducted on all…
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The AROMA Dataset for Automatic Detection of Artifact Type and Severity in Retinal Optical Coherence Tomography Angiography
Introduction: In recent years, retinal vascular imaging has attracted growing interest and is experiencing rapid technological advancements in imaging modalities such as swept-source optical coherence tomography angiography (SS OCT-A). OCT-A enables precise, noninvasive, quantitative measurements…
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Long-Term Follow-Up of Faricimab Intravitreal Injections in Naïve Neovascular Age-Related Macular Degeneration
Introduction: The aim of the study was to evaluate functional and anatomical changes at the 44-week follow-up in patients with naïve neovascular age-related macular degeneration (nAMD) treated with faricimab intravitreal injections (IVIs). Methods: Fifty-four eyes of 54 patients with naïve active…
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Accuracy of Intraocular Lens Power Calculation Formulas in Cataract Eyes after Vitrectomy with Silicone Oil Tamponade: A Network Meta-Analysis
Introduction: The aim of the study was to systematically compare the accuracy of artificial intelligence and traditional intraocular lens (IOL) calculation formulas in cataract eyes after vitrectomy with silicone oil tamponade. Methods: PubMed, Cochrane, Embase, and Web of Science databases were…
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Artikel Jurnal
Efficacy of Faricimab in Neovascular Age-Related Macular Degeneration: A Single-Arm Systematic Review and Meta-Analysis
Introduction: Neovascular age-related macular degeneration (nAMD) is a leading cause of vision loss and requires long-term anti-vascular endothelial growth factor therapy. This study aimed to evaluate the efficacy and safety of faricimab in patients with nAMD. Methods: This systematic review and…
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Donor Tissue Impact on Descemet Membrane Endothelial Keratoplasty Graft Preparation and Clinical Outcome
Introduction: Aims of the study were to determine which donor characteristics, like previous diseases and surgeries, influence the graft preparation difficulty of the Descemet membrane/endothelial lamella in DMEK surgery and to analyze the impact on the 1-year clinical outcome. Methods: Overall…
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Corneal Fluorescein Staining in FDA-Reviewed Dry Eye Registrational Clinical Trials: Evidence of Limited Endpoint Responsiveness
Introduction: Corneal fluorescein (FL) staining is the most widely used efficacy endpoint in dry eye disease (DED) registrational trials, yet dye diffusion and variable readout timing can blur punctate staining, reducing the precision and consistency of grading. We assessed the performance of FL…
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Artikel Jurnal
Long-Term Trends in the Global Burden of Age-Related Macular Degeneration: Sex Differences, Aging Effects, and Future Projections in Middle-Aged and Older Adults
Introduction: Age-related macular degeneration (AMD) is a major cause of irreversible vision loss in middle-aged and older populations worldwide. Understanding its long-term epidemiological trends is essential for anticipating future healthcare needs and guiding preventive strategies. This study…
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Artikel Jurnal
Cataract Surgery in Eyes with Microphthalmos and/or Uveal Coloboma
Introduction: Cataract may cause severe visual impairment in eyes with microphthalmos (MO) and uveal coloboma (UC). Despite their similarities, distinguishing between these conditions is crucial for cataract surgery. We aimed to compare complications, nucleus hardness, surgical strategies, and…
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Artikel Jurnal
The Change of Ciliary Muscle-Trabecular Meshwork-Schlemm Canal Complex after Phacoemulsification using Swept-Source-Optical Coherence Tomography
Introduction: Cataract surgery has been reported to have a reducing effect on intraocular pressure (IOP) in glaucomatous and non-glaucomatous eyes. This effect seems to be more noticeable in eyes with narrow angles (NAs) than in eyes with open angles (OAs). Decrease in IOP may be a result of the…