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Applied Microbiology and Biotechnology
Scopus
ISSN 1432-0614 · Springer · 584 articles in the index
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Journal Article
Photodynamic inactivation of Mycobacterium tuberculosis by broad-spectrum visible light
Abstract Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, a major infectious disease causing substantial global morbidity and mortality. The growing incidence of antibiotic-resistant strains highlights the urgency of identifying alternative strategies capable of targeting…
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Journal Article
A broadly applicable split-luciferase biosensor approach for rapid antibody detection in emerging infectious diseases
Abstract Conventional immunoassays such as ELISA are widely used in serological testing, yet their reliance on multi-step workflows and labeled reagents limits diagnostic scalability and speed. Bioluminescence-based biosensors are attractive alternatives that offer high sensitivity, operational…
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Journal Article
Burkholderia contaminans siderophore-rich supernatants suppress post-harvest anthracnose in avocado fruits
Abstract Siderophores are iron-chelating secondary metabolites that can effectively control fungal diseases in several agronomically important crops. In the present study, the bacterium Burkholderia contaminans MSR2 was found to profusely accumulate siderophores when grown under iron-limiting…
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Journal Article
Priestia megaterium reduces hydrogen sulfide level in swine manure potentially through an assimilatory mechanism and microbiota modulation
Abstract Noxious odors from swine farms pose significant health and environmental concerns. Hydrogen sulfide (H2S) is one of the major compounds causing noxious odors. Using biological inoculants offers a promising, efficient, and cost-effective method to reduce H2S emissions from these farms…
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Journal Article
N-Glycosylation of Band 3 is essential for the binding of Ganoderma lucidum immunomodulatory protein rLZ-8
Abstract Fungal immunomodulatory proteins (FIPs) are considered potential therapeutic candidates due to their immunomodulatory and anti-cancer activities. Meanwhile, they are capable of agglutinating mammalian red blood cells in a manner similar to lectins. Herein, GST-tagged rLZ-8, the first…
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Journal Article
Geographical traceability of bacteria based on a systematic stable isotope analysis method
Abstract The outbreak of certain bacteria can trigger severe diseases, even posing a threat to public safety, leading to significant social panic and economic losses. Thus, tracing the origin of bacteria is of great significance. Stable isotope analysis technology offers a new way to determine the…
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Journal Article
Production of uncommon carotenoids and lipids by red yeasts utilizing agri-food residues and waste cooking oil
Abstract In recent years, the biotechnological production of carotenoids and lipids by yeasts emerges as a valuable strategy at the industrial level, also fitting the circular economy pillars when agri-food waste can be used as the main components of the culture media. In this study, bioprocesses…
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Journal Article
Fluoride toxicity and mitigation strategies in acidophilic bioleaching microorganisms
Abstract Bioleaching is an established process for sulfidic ores and is increasingly applied to the recycling of industrial residues. However, unlike ores, many residues like sludge contain inhibitory elements, among which fluoride poses a major challenge due to its toxicity toward acidophilic…
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Journal Article
A newly isolated Streptomyces nigra strain for the biotechnological production of melanin
Abstract Melanins are pigments widely distributed in microbial, plant, and animal kingdoms. Their UV–visible light shielding capacity, metal chelation ability, antioxidant, and antimicrobial properties make these pigments suitable for different industrial applications like in cosmetic and…
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Journal Article
Engineering galactoside acetyltransferase for enhanced hesperetin-7-O-glucoside bioavailability
Abstract Flavonoid glycosides exhibit compromised bioavailability due to low membrane permeability. To address this limitation, we acetylated flavonoids through enzymatic reactions to increase bioavailability. This study first reported that Hesperetin-7-O-glucoside (Hes-7-G) was acetylated by…
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Journal Article
Precision hydrolysis: tailored yeast processing enzymes for yeast-based products
Abstract Yeasts and yeast-based products are nutrient-rich bioresources with broad applications in technologies for the production of food, feed, medicine, and cosmetics. However, traditional processing often results in non-specific lysis and suboptimal product quality. Yeast extract can be used as…
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Journal Article
Cosolvent-induced spontaneous refolding of lipase
Abstract The overexpression of proteins in Escherichia coli often results in the formation of inclusion bodies, which are biologically inactive, especially for proteins with exposed hydrophobic surfaces. Solubilization of inclusion bodies (IBs) and subsequent refolding is essential for obtaining…
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Journal Article
Evaluation of the delivery of an anti-Listeria endolysin via CRISPR-Cas9 engineered probiotic Saccharomyces boulardii
Abstract Listeriosis is a foodborne infection caused by Listeria monocytogenes that causes febrile gastroenteritis and central nervous system infections and that can often lead to fatality. Upon consumption of contaminated food, Listeria is able to survive a number of gastrointestinal stressors…
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Journal Article
Nanoparticle-based approaches for bacterial detection and therapy
Abstract The advent of nanotechnology has revolutionised approaches to identifying and combating bacterial infections. This review highlights the latest applications of nanoparticles (NPs) for bacterial detection and treatment, with a focus on their translational potential in clinical settings. We…
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Journal Article
Virus-like particle (VLP)-based indirect ELISA (iELISA) for the detection of beak and feather disease virus (BFDV) antibodies
Abstract Beak and feather disease virus (BFDV) poses a significant threat to avian biodiversity and global aviculture. Reliable serodiagnostic tools are critical for assessing host immune status and guiding disease management. The haemagglutination inhibition (HI) assay, although historically…
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Journal Article
Characterization, genomic analysis, and decontamination application of a novel Vibrio phage BUCT787 on salmon fillets
Abstract Vibrio spp. are significant zoonotic pathogens in seafood, causing human gastroenteritis and posing challenges to the aquaculture industry. The misuse of antibiotics in aquaculture has led to the rise of antibiotic-resistant strains, necessitating alternative solutions like phages for food…
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Journal Article
Blue LED–assisted bioreactor cultivation enhances carotenoid accumulation in Rhodotorula mucilaginosa LB-01
Abstract Microbial production of carotenoids provides a sustainable alternative to plant-derived sources. In this study, a yeast strain, Rhodotorula mucilaginosa LB-01, was isolated and its carotenoid biosynthetic potential was evaluated. Medium optimization (10 g/L glucose and 3 g/L yeast extract)…
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Journal Article
Fusarium enrichment alters the soil microbial community and network structure of Brassica crops
Abstract Soil-borne microbial diseases constitute a significant constraint on crop production, causing substantial annual economic losses estimated at 40%–60% in agricultural sectors. This study aimed to identify the principal plant pathogens causing diseases in Brassica crops in Ningxia, China…
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Journal Article
Multistep metabolic engineering of Pichia pastoris for biosynthesis of N‑acetylneuraminic acid
Abstract Free or protein-conjugated N-Acetylneuraminic acid (Neu5Ac) is widely distributed in organisms and possesses diverse biological functions, and for example lactoferrin with Neu5Ac-mediated sialylation exhibits significantly enhanced functional activity compared with non-sialylated…