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Transplant International
Scopus
ISSN 1432-2277 · Frontiers Media S.A. · 682 artikel di indeks
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Artikel Jurnal
Understanding Machine Learning Applications in Lung Transplantation: A Narrative Review
Lung transplantation (LTx) offers life-saving therapy for patients with end-stage lung disease but remains limited by donor shortages, complex postoperative management and graft failure. Machine learning (ML) enables opportunities to address these challenges by identifying patterns in complex…
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Artikel Jurnal
CNI Trough Variability Does Not Reliably Reflect Medication Adherence: Insights From a 3-Year Follow-Up Study
Calcineurin inhibitor (CNI) trough concentrations and their variability are frequently used as adherence proxies, despite limited validation. We evaluated the association between self-reported adherence and CNI exposure during the first year after kidney transplantation. We included 619 patients…
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Artikel Jurnal
Kidney Transplantation in Western Balkans: A Regional Blueprint for Access, Capacity, and Equity
There is no medical field where the impact of medical evolution is more palpable than in kidney transplantation. The pioneers of this procedure, 70 years ago, laid out the foundation for organ transplantation in general and kidney transplantation in particular. Despite the incredible advancements…
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Artikel Jurnal
A Prospective Multicenter Luminex-Based Clinical Algorithm to Define Unacceptable HLA Mismatches Before Kidney Transplantation. Consequences on Outcome, Waiting Time, and Wait List Composition
Determination of unacceptable human leukocyte antigen (HLA) mismatches (UAM) before kidney transplantation (KT) aims at minimizing immunological risk and routinely involves Luminex single antigen bead (SAB) testing. SAB-UAM criteria, however, often lack standardization. We implemented standardized…
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Artikel Jurnal
Longitudinal Monitoring of Donor-Derived Cell-Free DNA Supports Risk Stratification in Kidney Transplant Recipients With Allograft Dysfunction
The prognostic value of donor-derived cell-free DNA (dd-cfDNA) for long-term kidney allograft outcomes after indication biopsy remains incompletely defined. In this prospective single-center cohort, 106 kidney transplant recipients with 108 indication biopsies were assessed for dd-cfDNA at biopsy…
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Artikel Jurnal
Combined Creatinine and Cystatin C Equations Improve Estimation of Glomerular Filtration Rate in Kidney Transplant Recipients
Glomerular filtration rate (GFR) is a crucial parameter in post-transplant follow-up (PTF). CKD-EPI 2009 creatinine-based equation remains the most used estimated GFR (eGFR) and only few data are available on the other equations, based on creatinine, cystatin C or their combination. We evaluated 10…
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Artikel Jurnal
The Multidisciplinary Support To Access living donor Kidney Transplant (MuST AKT) intervention: A Pilot Randomized Controlled Trial
We evaluated the feasibility and acceptability of the Multidisciplinary Support To Access living donor Kidney Transplant (MuST AKT) intervention, developed to increase living donor kidney transplantation (LDKT). In this pilot randomized controlled trial, we randomly assigned transplant candidates…
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Artikel Jurnal
Donor-Derived Cell-Free DNA as a Non-Invasive Readout of Activity Across the Rejection Continuum
Recent work demonstrated that kidney allograft rejection unfolds along a biological continuum that can be quantified using histopathology-derived continuous indices. To investigate whether donor-derived cell-free DNA (dd-cfDNA) reflects this rejection continuum and complements these…
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Artikel Jurnal
Novel Allocation Strategies Can Boost Kidney Exchange Programs: A Monte Carlo Simulation
Kidney exchange programs (KEPs) enhance access to living donor kidney transplantation. Nonetheless, transplant rates in KEP remain low for highly immunized and blood type O patients. In the Netherlands, a novel allocation algorithm is being implemented, allowing ABO-incompatible matching for long…
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Artikel Jurnal
Impact of Vascular Anastomosis Time on Kidney Transplant Outcomes – A Systematic Review
Anastomotic time (AT), also termed second warm ischaemic time (SWIT), is a potentially important intraoperative factor in kidney transplantation, yet its impact on outcomes has not been systematically synthesised. We conducted a systematic review to examine the association between AT and delayed…
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Artikel Jurnal
Age-Related Risk After Kidney Transplantation: A Comprehensive Analysis of Infection Burden, Graft Outcomes, and Mortality
Given the increasing number of kidney transplantation in elderly recipients, understanding age-specific risks is essential for optimized post-transplant care. We analyzed 572 kidney transplant recipients from the DZIF Transplant Cohort (2012–2023), stratified by age: <40 (n = 146), 40–60 (n = 279)…
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Artikel Jurnal
Multicentre Collaborative Prospective Cohort Study Investigating the Impact of Enhanced Recovery After Surgery on Kidney Transplant Outcomes: The CRAFT Study
Perioperative complications are common in kidney transplantation. Enhanced recovery after surgery (ERAS) is a well-established multimodal perioperative care pathway designed to improve patient outcomes, however, its efficacy in renal transplant remains poorly described. Participating centres…
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Artikel Jurnal
Association Between Three Lung Donor Scores and Lung Acceptance in DBD and DCD Donors
The use of extended criteria donors (ECD) has become increasingly important in lung transplantation to address organ donor shortages. To better assess lung graft quality and optimize donor selection, several scores have been developed. This study assesses whether Swiss lung acceptance practice is…
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Artikel Jurnal
Cellular Immunity in Chronic Kidney Disease and Changes After Kidney Transplantation
This study evaluates changes in cellular immunity components, from chronic kidney disease stage V (CKD-V) to long-term transplantation (lKTx). We applied flow cytometry to determine total, CD4+, CD8+, CD28− T-lymphocytes, Natural killer cells (NK) and regulatory T-lymphocytes (Tregs), in peripheral…
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Artikel Jurnal
Donor-Derived Cell-Free DNA in Pancreas-Kidney, Heart-Kidney, and Liver-Kidney Multiorgan Transplant Recipients (MOTR)
Donor-derived cell free DNA (dd-cfDNA) is an established biomarker for detection of rejection in single organ transplants; data is limited in multi-organ transplant (MOT) recipients. “Use of dd-cfDNA in Multi-Organ Transplant Recipients” (MOTR) was a multicenter, prospective, cross-sectional study…