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Clinical Medicine
Scopus
ISSN 1470-2118 · Elsevier · 386 artikel di indeks
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Artikel Jurnal
Impact of patient safety on hospital prognosis: Association between adverse events and in-hospital mortalit
Introduction: Adverse events (AEs) involve a safety problem and compromise the quality of care, but evidence on how they affect the prognosis of patients is limited. Objective: In this study, the relationship between the presence of AEs and in-hospital mortality among patients is analysed, and…
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Artikel Jurnal
Antibodies and distortion of insulin and C-peptide results in patients with hypoglycaemia of unknown origin
Two types of antibody could confuse the differential diagnosis of hypoglycaemia. One is insulin-binding autoantibodies (IAA), a double hit causing hypoglycaemia of insulin autoimmune syndrome (IAS, also known as Hirata’s disease) as well as distorting measurements of insulin and/or C-peptide. The…
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Associations of metabolic syndrome and albuminuria with all-cause mortality in patients with coronary artery disease and no history of diabetes: A cohort study
Background: Metabolic syndrome is a constellation of cardiovascular risk factors and has been associated with a higher risk of mortality. Albuminuria was previously part of the criteria for metabolic syndrome. We investigated the associations of albuminuria and metabolic syndrome with all-cause…
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The clinical effective of sodium/glucose co-transporter-2 inhibitors on admission frequency, duration and use of acute non-invasive ventilation in patients with chronic obstructive pulmonary disease: A single-centre 24-month retrospective observational study in a UK tertiary care centre
Background: Chronic obstructive pulmonary disease (COPD) contributes significantly to global morbidity and mortality and high economic burdens to healthcare systems. Emerging evidence suggests that sodium/glucose co-transporter-2 inhibitors (SGLT2i), beyond their use in type 2 diabetes mellitus…
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Salmonella enteritidis meningitis in an immunocompetent adult
Invasive Salmonella infection is associated with high morbidity and mortality. It commonly affects patients who are immunocompromised or at extremes of age. We report an unusual case of a previously well 50-year-old gentleman with disseminated Salmonella infection. He presented with left…
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Outcomes following nurse-led day-case paracentesis
Background: Therapeutic paracentesis (TP) is a key symptom-relieving intervention in refractory ascites. In response to rising demand, Nottingham University Hospitals NHS Trust was among the first UK centres to introduce a nurse-led, day-case TP service. This study evaluates the complications and…
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Diabetes and technology – an update for the general physician
Diabetes is a growing public health concern. Approximately 20% of acute NHS hospital beds are occupied by individuals with diabetes. Following the recent NICE (National Institute for Health and Care Excellence) updates, diabetes technologies are increasingly available in the NHS. Despite the…
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Diabetes and the liver
Type 2 diabetes mellitus (T2D) and metabolic dysfunction-associated steatotic liver disease (MASLD), formerly termed non-alcoholic fatty liver disease (NAFLD), are increasingly prevalent conditions that are closely associated. The shared pathophysiology of insulin resistance, chronic inflammation…
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Evaluating hepatocellular carcinoma (HCC) surveillance through an early diagnostic centre: An implementation science approach at a tertiary hepatology centre in England
Background: Hepatocellular carcinoma (HCC) has high mortality, improved by early diagnosis. An integrated service was established to facilitate timely cancer surveillance. Aims: Evaluate the utility of an early diagnostic centre (EDC) in diagnosis of liver cancer. Methods: Retrospective analysis of…
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Reducing inappropriate inpatient blood glucose monitoring
Inpatient blood glucose monitoring (BGM) is prevalent, while healthcare costs and workforce demands are rising. We aimed to identify causes of unnecessary monitoring and assess effectiveness of targeted interventions, to maximise healthcare resources while prioritising patient safety.Clinical…
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Diabetes and transplantation
Transplantation is both a cause of, and a therapy for, diabetes. Solid organ transplantation requires immunosuppressive regimens that frequently cause temporary or permanent hyperglycaemia, which can influence the outcome of allograft function and also increase cardiovascular mortality and…
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Diabetes and the kidney
Diabetic kidney disease (DKD) management has become increasingly complex. For non-specialists in diabetes or kidney disease, there are some basic standards of care that apply to all people with DKD. These include blood glucose optimisation, blood pressure management, renin–angiotensin–aldosterone…
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Diabetes and the heart
Diabetes mellitus and cardiac problems frequently coexist, posing significant challenges for both generalists and specialists. This article discusses the common cardiac manifestations of diabetes including coronary artery disease, heart failure and arrythmia, outlining specific diagnostic…
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Musculoskeletal manifestations of diabetes mellitus – an update
Diabetes mellitus is an increasingly prevalent condition, with an estimated 1.3 billion people projected to be affected by 2050, and can reduce life expectancy by up to 20 years. Musculoskeletal complications are present in more than half of patients with diabetes and lead to significant morbidity…
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Can hepatology lead the way? Synthesising current global curricula and proposing a model for an international specialty curriculum
Background: Increased understanding and treatments for liver disease have led in recent decades to the emergence of hepatology as a subspecialty within gastroenterology, and as a standalone medical specialty. Growing challenges in hepatology are a global problem, yet no global framework for…
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Smoking, health and social justice
Background: National smoking prevalence is declining and new legislation, such as the Tobacco and Vapes Act, will reduce the number of people who take up smoking. However, there are profound disparities in the prevalence of people who currently smoke in the population, and further measures are…