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Nature reviews. Neuroscience
Scopus
ISSN 1471-003X · Nature Portfolio · 36 articles in the index
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The language network as a natural kind within the broader landscape of the human brain
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Astrocyte contribution to dysfunction, risk and progression in neurodegenerative disorders
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Genomics, convergent neuroscience and progress in understanding autism spectrum disorder
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Mechanisms governing activity-dependent synaptic pruning in the developing mammalian CNS
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Cognitive and behavioural flexibility: neural mechanisms and clinical considerations
Cognitive and behavioural flexibility permit the appropriate adjustment of thoughts and behaviours in response to changing environmental demands. Brain mechanisms enabling flexibility have been examined using non-invasive neuroimaging and behavioural approaches in humans alongside pharmacological…
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Environmental influences on the pace of brain development
Childhood socio-economic status (SES), a measure of the availability of material and social resources, is one of the strongest predictors of lifelong well-being. Here we review evidence that experiences associated with childhood SES affect not only the outcome but also the pace of brain…
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The probabilistic model of Alzheimer disease: the amyloid hypothesis revised
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Neurexins: molecular codes for shaping neuronal synapses
The function of neuronal circuits relies on the properties of individual neuronal cells and their synapses. We propose that a substantial degree of synapse formation and function is instructed by molecular codes resulting from transcriptional programmes. Recent studies on the Neurexin protein…
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Untangling the cortico-thalamo-cortical loop: cellular pieces of a knotty circuit puzzle
Functions of the neocortex depend on its bidirectional communication with the thalamus, via cortico-thalamo-cortical (CTC) loops. Recent work dissecting the synaptic connectivity in these loops is generating a clearer picture of their cellular organization. Here, we review findings across sensory…