50 hasil

microRNAs in action: biogenesis, function and regulation

Renfu Shang; Seungjae Lee; Gayan Senavirathne dkk.

Nature Reviews Genetics · 2023 · Inggris · OpenAlex Scopus

Non-coding RNAs in disease: from mechanisms to therapeutics

Kinga Németh; Recep Bayraktar; Manuela Ferracin dkk.

Nature Reviews Genetics · 2023 · Inggris · OpenAlex Scopus

Autophagy genes in biology and disease

Hayashi Yamamoto; Sidi Zhang; Noboru Mizushima

Nature Reviews Genetics · 2023 · Inggris · OpenAlex Scopus

Primary cilia as dynamic and diverse signalling hubs in development and disease

Pleasantine Mill; Søren T. Christensen; Lotte B. Pedersen

Nature Reviews Genetics · 2023 · Inggris · OpenAlex Scopus

Best practices for single-cell analysis across modalities

Lukas Heumos; Anna C. Schaar; Christopher Lance dkk.

Nature Reviews Genetics · 2023 · Inggris · OpenAlex Scopus

Methods and applications for single-cell and spatial multi-omics

Katy Vandereyken; Alejandro Sifrim; Bernard Thienpont dkk.

Nature Reviews Genetics · 2023 · Inggris · OpenAlex Scopus

Principles and methods for transferring polygenic risk scores across global populations

Linda Kachuri; Nilanjan Chatterjee; Jibril Hirbo dkk.

Nature Reviews Genetics · 2023 · Inggris · OpenAlex Scopus

RNA modifications in physiology and disease: towards clinical applications

Sylvain Delaunay; Mark Helm; Michaela Frye

Nature Reviews Genetics · 2023 · Inggris · OpenAlex Scopus

Incongruence in the phylogenomics era

Jacob L. Steenwyk; Yuanning Li; Xiaofan Zhou dkk.

Nature Reviews Genetics · 2023 · Inggris · OpenAlex Scopus

Molecular mechanisms of environmental exposures and human disease

Haotian Wu; C. Eckhardt; Andrea Baccarelli

Nature Reviews Genetics · 2023 · Inggris · OpenAlex Scopus

Alternative splicing as a source of phenotypic diversity

Charlotte J Wright; Christopher W. J. Smith; Chris D. Jiggins

Nature Reviews Genetics · 2022 · Inggris · OpenAlex Scopus

Biological roles of adenine methylation in RNA

Konstantinos Boulias; Eric Lieberman Greer

Nature Reviews Genetics · 2022 · Inggris · OpenAlex Scopus

Molecular mechanisms of transgenerational epigenetic inheritance

Maximilian Fitz-James; Giacomo Cavalli

Nature Reviews Genetics · 2022 · Inggris · OpenAlex Scopus

Prime editing for precise and highly versatile genome manipulation

Peter J. Chen; David R. Liu

Nature Reviews Genetics · 2022 · Inggris · OpenAlex Scopus

Measuring biological age using omics data

Jarod Rutledge; Hamilton Oh; Tony Wyss‐Coray

Nature Reviews Genetics · 2022 · Inggris · OpenAlex Scopus

Drug delivery systems for RNA therapeutics

Kalina Paunovska; David Loughrey; James E. Dahlman

Nature Reviews Genetics · 2022 · Inggris · OpenAlex Scopus

Human organs-on-chips for disease modelling, drug development and personalized medicine

Donald E. Ingber

Nature Reviews Genetics · 2022 · Inggris · OpenAlex Scopus

The failure of animal models to predict therapeutic responses in humans is a major problem that also brings into question their use for basic research. Organ-on-a-chip (organ chip) microfluidic devices lined with living cells cultured under fluid flow can recapitulate organ-level physiology and…

Genetics of circadian rhythms and sleep in human health and disease

Jacqueline M. Lane; Jingyi Qian; Emmanuel Mignot dkk.

Nature Reviews Genetics · 2022 · Inggris · OpenAlex Scopus

Probing the dynamic RNA structurome and its functions

Robert C. Spitale; Danny Incarnato

Nature Reviews Genetics · 2022 · Inggris · OpenAlex Scopus

RNA is a key regulator of almost every cellular process, and the structures adopted by RNA molecules are thought to be central to their functions. The recent fast-paced evolution of high-throughput sequencing-based RNA structure mapping methods has enabled the rapid in vivo structural interrogation…

Genetics of human telomere biology disorders

Patrick Revy; Caroline Kannengiesser; Alison A. Bertuch

Nature Reviews Genetics · 2022 · Inggris · OpenAlex Scopus