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BMC Genomics
Scopus
ISSN 1471-2164 · BMC · 14.295 artikel di indeks
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Artikel Jurnal
Multiomics transcriptome and metabolome insights into fat metabolism and meat quality in Songliao black pigs and Songlei crossbred pigs
Abstract Background The rising demand for high-quality pork among consumers has driven interest in genetic improvement strategies. Crossbreeding is well known to influence carcass performance and meat quality; however, the molecular mechanisms underlying these effects are still poorly understood…
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Artikel Jurnal
Identification of a complex chromosomal insertion using the chromosome conformation based karyotyping technique for the implementation of PGT-SR
Abstract Objective This study completed the karyotyping of a patient with a complex chromosomal insertion and identified the location of the breakpoint for implementing preimplantation genetic testing for chromosomal structural rearrangements (PGT-SR) to differentiate between normal and carrier…
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Artikel Jurnal
Distribution and shared evolutionary history of the Fumonisin and AAL toxin biosynthetic gene clusters
Abstract Background Fumonisins are among the mycotoxins of most concern to food safety and are structurally similar to AAL toxins, a family of host selective toxins. Together, these two toxin families are produced by ecologically diverse species in three fungal classes: AAL toxins by Alternaria…
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Artikel Jurnal
Identification and characterization of the class III peroxidase gene family in sea buckthorn (Hippophae rhamnoides subsp. sinensis Rousi) and its potential role in lignin biosynthesis
Abstract Background Class Ⅲ peroxidases (PODs) are widely involved in multiple physiological processes, including lignin biosynthesis and stress responses. However, there are no reports on the identification and function of POD family in Hippophae rhamnoides subsp. sinensis Rousi. Results In this…
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Artikel Jurnal
Population structure, regions of homozygosity (ROH) and selection signal of two domesitic goat breeds revealed by whole-genome resequencing
Abstract Background Chinese indigenous goat breeds exhibit rich genetic diversity and a long history of domestication, endowing these native populations with superior traits in environmental adaptation, forage utilization, and disease resistance. The identification of selection signatures through…
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Artikel Jurnal
Comprehensive transcriptomic profiling identifies key regulatory genes mediating phytohormone signaling pathways during seed germination in Chenopodium quinoa
Abstract Background Pre-harvest sprouting (PHS) significantly reduces the yield and quality of Chenopodium quinoa (quinoa). A key determinant of PHS resistance is the balance between seed dormancy and germination, a process primarily regulated by phytohormones. Results To elucidate the molecular…
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Artikel Jurnal
Building consensus: construction of a juvenile and adult scRNA-seq meta-atlas for dataset comparisons and harmonizing transcriptomic definitions of enteric neuron subtypes
Abstract Background The enteric nervous system (ENS) is a complex network of interconnected ganglia within the gastrointestinal (GI) tract. Among its diverse functions, the ENS detects bowel luminal contents and coordinates the passing of stool. ENS defects predispose to GI motility disorders…
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Artikel Jurnal
Genome-wide identification, characterization, and expression analyses of the solute carrier 2 (SLC2) gene family in fall armyworm (Spodoptera frugiperda)
Abstract The solute carrier 2 (SLC2) gene family, responsible for hexose and polyol transport, has not been fully characterized in Spodoptera frugiperda, a globally invasive pest. Among this family, the trehalose transporter (TRET) genes, the largest and most functionally important subfamily…
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Artikel Jurnal
Insights into the host response to ‘dormant’ Mycobacterium tuberculosis utilizing ‘Vitamin C-induced dormant Mtb’ THP-1 cell infection model
Abstract Background During a latent tuberculosis infection, there exists a dynamic equilibrium between the host and the ‘dormant’ bacterium wherein they mutually influence each other. An understanding of the host genetic response to ‘dormant’ tubercle bacilli during infection is necessary for…
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Artikel Jurnal
Transcriptomic analysis of differentially expressed genes associated with growth, meat quality, and fatty acid metabolism in Sunit lambs under varying rearing conditions
Abstract Background Pasture-based feeding is generally associated with superior meat quality, particularly in terms of favorable fatty acid profiles, whereas concentrate-based feeding typically promotes faster growth and higher productivity, albeit often at the expense of certain aspects of meat…
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Artikel Jurnal
Whole-genome sequencing of Apis mellifera lamarckii: first comprehensive genomic atlas of Egyptian honeybees reveals pathogen resistance mechanisms and local adaptation signatures
Abstract This study presents the first comprehensive genomic atlas of Egypt’s native honeybee, Apis mellifera lamarckii. Along with the Morphometric Assessment, a thorough examination of A. m. lamarckii workers and taxonomical characterization was conducted. Using PacBio long-read sequencing and…
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Artikel Jurnal
Cookbook for plant genome sequences
Abstract Access to genome sequences is crucial to investigate and engineer traits in plants, explore biodiversity, and support phylogenetic studies. Over the last decade, affordable sequencing devices have substantially increased the size of the genomics community by enabling individual research…
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Artikel Jurnal
Community assembly modeling of the microbiome within Barrett’s esophagus and esophageal adenocarcinoma
Abstract Computational modeling of somatic evolution, a process shaped by ecology and impacting both host cells and microbial communities in the human body, can capture important dynamics driving carcinogenesis. Here we considered models for esophageal adenocarcinoma (EAC), a cancer that has…
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Artikel Jurnal
Genomic and functional characterization of Pseudosulfitobacter pseudonitzschiae BPC-C4-2: a growth-promoting symbiont in Antarctic Ulva communities
Abstract Background Pseudosulfitobacter pseudonitzschiae is a species within the genus Pseudosulfitobacter, which belongs to the Roseobacteraceae. This family is closely associated with algae and is essential to marine ecosystems, particularly through interactions with phytoplankton. Notably, this…
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Artikel Jurnal
Exploring Pinus nigra's induced defense arsenal against Diplodia sapinea through gene and metabolic pathway analysis
Abstract The European black pine (Pinus nigra J. F. Arnold) is a conifer of high economic and ecological importance and is considered a potential alternative to several forest tree species in Central Europe to support adaptation to global climate warming. However, the fungus Diplodia sapinea (Fr.)…
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Artikel Jurnal
Integrated co-expression analysis of host–parasite transcriptomes reveals mechanisms of host modulation in an ant–cestode system
Abstract How parasites interact with their hosts at the molecular level is a central question in parasitology, yet identifying host pathways directly targeted by parasites is challenging because infections often have broad effects on host physiology. This difficulty is particularly pronounced in…
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Artikel Jurnal
Genome-wide characterization of OFP family in soybean reveals the roles of GmOFP genes involved in plant height regulation and salinity tolerance
Abstract Background Ovate Family Proteins (OFPs), a class of plant-specific transcription factors, play vital roles in development and abiotic stress tolerance. However, the OFP family in soybean (Glycine max) has not been extensively studied. Results In this study, a total number of GmOFP genes…
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Artikel Jurnal
Whole genome sequencing revealed genetic diversity, population structure, and selective signature of Tianhua mutton sheep
Abstract Background Sheep have diversified into distinct breeds worldwide through both natural adaptation and human-driven selection, with hybridization serving as an effective strategy for rapid trait improvement. The Tianhua mutton sheep (TMS) is a novel breed derived from crossing South African…
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Artikel Jurnal
Avirulence genes identified through linkage mapping and region-specific association studies in the wheat leaf rust pathogen Puccinia triticina
Abstract Background Wheat rust fungi can cause significant damage to wheat crops, leading to reduced yields and economic losses. To combat disease, certain plant varieties can trigger defense responses upon recognition of specific pathogen effector proteins, thereby conferring avirulence…
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Artikel Jurnal
Genomic signatures of environmental adaptation in Danzhou chickens
Abstract Background Danzhou chicken (DZC) is a native chicken breed endemic to Hainan Island, which is renowned for its superior meat quality and strong disease resistance. Prolonged geographical isolation, coupled with natural and artificial selection events in response to the tropical…
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