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BMC Cancer
Scopus
ISSN 1471-2407 · BMC · 16,787 articles in the index
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Journal Article
Conversion surgery vs. standard of care in pancreaTic cancer oligometastatic to the liver (SONAR: Surgery in Oligometastatic paNcreatic cAnceR) a randomized controlled trial
Abstract Background Pancreatic cancer oligometastatic to the liver represents a distinct subset of advanced disease, presenting a limited number of metastases in a single site. First-line chemotherapy is considered the standard of care, with a poor overall prognosis. However, the optimal strategy…
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Journal Article
Integrative transcriptomic profiling reveals subtype-specific therapeutic vulnerabilities and resistance mechanisms in prostate cancer
Abstract Objective Advanced prostate cancer (PCa) remains therapeutically challenging due to heterogeneous mechanisms of resistance to androgen receptor (AR)-targeting agents. While AR signaling persists in castration-resistant PCa (CRPC), emerging evidence suggests AR-independent survival pathways…
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Journal Article
Perceived exertion for guiding and monitoring exercise intensity in unsupervised, home-based cancer rehabilitation: an analysis of 3533 exercise sessions
Abstract Background Exercise therapy is an essential part of cancer rehabilitation. Home-based, unsupervised exercise programs supported by digital tools offer a promising way to reduce access barriers. However, guiding and monitoring exercise intensity without supervision remains difficult. Rating…
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Journal Article
The effects of certification of head and neck cancer centers on the survival of patients with a head and neck cancer
Abstract Introduction Head and neck cancers represent a heterogeneous group of tumor in terms of both, their entity and location. This includes cancers of the lip, oral cavitiy, pharynx (epi-, oro- and hypopharynx), larynx, nasal cavity/ sinus and salivary gland. Additionally, they are associated…
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Journal Article
Scrutinizing the potential role of non-coding RNAs as biomarkers in Egyptian females with early and metastatic breast cancer
Abstract Background Breast cancer (BC) is the second most frequently diagnosed malignancy worldwide and the most common cancer among Egyptian women, accounting for 38.8% of female malignancies. Early diagnosis is critical for improving outcomes; however, conventional serum tumor markers such as CEA…
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Journal Article
Implementing cancer prevention in occupational healthcare: initial insights from occupational healthcare staff in Central and Southern Europe – findings from the CPW project
Abstract Background Effective primary cancer prevention in occupational health care settings requires strategies tailored to workforce needs and individual risk profiles. Cultural, perceptual, and behavioural factors influence implementation success. Occupational healthcare professionals (OHCPs)…
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Journal Article
Evaluation of magnetic resonance imaging parameters and compliance with guidelines in soft tissue sarcomas
Abstract Background Accurate imaging plays a crucial role for prognostic assessment and treatment allocation in soft tissue sarcoma (STS). Guidelines recommend contrast-enhanced magnetic resonance imaging (MRI) including diffusion-weighted imaging (DWI) for tumor assessment. This study aims to…
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Journal Article
Response assessment of patients with locally advanced renal cell carcinoma receiving prior systemic therapy
Abstract Background Locally advanced renal cell carcinoma (RCC) without distant metastases remains challenging to treat surgically, especially when venous tumor thrombus is present. Neoadjuvant checkpoint inhibitor (CPI) and tyrosine kinase inhibitor (TKI) therapy may downstage tumors and improve…
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Journal Article
Glucose-transporter 1 (GLUT1) as a prognostic biomarker: evidence from 14,966 human tumors across 134 cancer types
Abstract Background Glucose transporter 1 (GLUT1) is a key protein for transmembranous glucose uptake of cells which is often overexpressed in cancer. Methods To better comprehend the prevalence and role of GLUT1 expression in different cancer types, a tissue microarray containing 14,966 samples…
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Journal Article
Elevated levels of SLC38A1 are correlated with an unfavorable prognosis, as well as accelerated cell proliferation and metastasis in lung adenocarcinoma
Abstract Background SLC38A1 has been identified as a carcinogenic factor in the progression of colorectal, gastric, pancreatic, and other cancers. However, its involvement in lung adenocarcinoma (LUAD) remains unexplored in the literature. Methods The expression levels, diagnostic relevance, and…
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Journal Article
Dietary intervention reshapes gut microbiota and lipid metabolism to enhance anti-tumor immunity and prognosis in hepatocellular carcinoma: a randomized controlled trial
Abstract Background The gut microbiota is increasingly recognized as a key modulator of cancer pathogenesis and treatment response. We aimed to investigate the efficacy of a targeted dietary intervention on clinical outcomes, gut microbiota, lipid metabolism, and systemic immunity in patients with…
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Journal Article
KRAS mutation and its association with clinicopathological features of colorectal cancer patients in Africa: a systematic review and meta-analysis
Abstract Background Mutations in the KRAS gene serve as significant oncogenic drivers in colorectal cancer (CRC), greatly affecting therapy response and prognosis. While the prevalence and clinical significance of KRAS mutations have been extensively documented in Western populations, information…
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Journal Article
“Prevalence of sexual dysfunction and narrative synthesis of associated factors in patients with different type of cancer: a systematic review and meta-analysis”
Abstract Background Sexual dysfunction (SD) is a prevalent but underrecognized consequence of cancer and its treatment, affecting patients’ quality of life, psychological well-being, and intimate relationships. Despite its clinical importance, the literature on SD remains fragmented, with previous…
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