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Thrombosis Journal
Scopus
ISSN 1477-9560 · BMC · 926 artikel di indeks
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Artikel Jurnal
The unexpected clot: unilateral brachial artery occlusion unmasking antithrombin III deficiency; case report and therapeutic considerations
Abstract Background Antithrombin III (AT III) deficiency is a rare autosomal dominant thrombophilia that typically predisposes carriers to venous thromboembolism. Arterial thrombosis is uncommon but may occur in severe quantitative or qualitative defects, particularly when compounded by exogenous…
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Artikel Jurnal
Characterization of anticoagulated patients in a Latin American country: indications, treatment patterns, and complications
Abstract Introduction Thromboembolic disorders remain a leading cause of morbidity and mortality. Although anticoagulation therapy (AT) has reshaped practice worldwide, real-world data on AT use and outcomes in Latin America, particularly Colombia, are scarce. To bridge this gap, we established the…
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Artikel Jurnal
The interaction of fibrinolysis and the complement system in patients with acute pulmonary embolism, treated with ultrasound-assisted catheter-directed thrombolysis
Abstract Ultrasound-assisted catheter-directed thrombolysis (USAT) with recombinant tissue-type plasminogen activator (rt-PA) is widely used as a reperfusion approach for acute pulmonary embolism (PE). The fibrinolytic effector protease plasmin is known to be a potent activator of the complement…
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Artikel Jurnal
Portal vein thrombosis as a clinical dilemma in Echis carinatus envenomation: a case report and review of the literature
Abstract Background Snakebite envenoming is a major neglected tropical disease, particularly in rural regions of tropical and subtropical countries. Echis carinatus (saw-scaled viper; SSV), prevalent in the desert regions of Iran, is a medically significant species of the Viperidae family whose…
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Artikel Jurnal
Qiliqiangxin capsule attenuates platelet activation and thrombosis by suppressing Ca2+ influx and PKC signaling
Abstract Background Arterial thrombotic diseases are leading causes of global morbidity and mortality, primarily driven by platelet hyperactivity. Qiliqiangxin capsules (QLQX), a traditional Chinese medicine approved in China for the treatment of heart failure, have exhibited potential benefits in…
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Artikel Jurnal
2 cases of pegylated asparaginase-associated cerebral venous sinus thrombosis in children: clinical analysis and literature review
Abstract Background Cerebral venous sinus thrombosis (CVST) is a serious complication in children with acute lymphoblastic leukemia (ALL) undergoing chemotherapy with pegylated asparaginase (PEG-Asp). This study aims to investigate its risk factors, clinical features, and prognosis. Methods We…
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Artikel Jurnal
Perioperative management in a patient with congenital factor VII deficiency following mechanical valve replacement: a case report
Abstract Background Congenital factor VII deficiency (CFVIID) is a rare hemorrhagic disorder which elevates perioperative bleeding risks. Mechanical prosthesis mandates lifelong anticoagulation, while international normalized ratio (INR) of CFVIID deviates significantly from the normal range which…
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Artikel Jurnal
Recurrent venous thrombosis in an adolescent male with CBS mutation and persistent antiphospholipid antibody positivity: a case report
Abstract Homocysteine (Hcy) contributes to endothelial dysfunction and impaired thrombolysis, and genetic polymorphisms that elevate plasma Hcy concentrations have been linked to an increased risk of thrombosis. Notably, mutations in the cystathionine β-synthase (CBS) gene, which reduce enzymatic…
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Artikel Jurnal
Popliteal vein aneurysm presenting in a patient with cerebral infarction and patent foramen ovale: a rare case with complex thrombotic events
Abstract Popliteal vein aneurysm (PVA) is a rare yet potentially serious vascular lesion that can lead to various complications, including thrombosis and pulmonary embolism. This case study examines a 29-year-old female patient whose cerebral infarction may have resulted from a thrombus within the…
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Artikel Jurnal
Efficacy, safety, and influencing factors of AngioJet mechanical thrombectomy versus catheter-directed thrombolysis in the treatment of acute lower limb deep vein thrombosis
Abstract Objective This study compared the efficacy and safety of AngioJet mechanical thrombectomy and catheter-directed thrombolysis (CDT) in acute lower limb deep vein thrombosis (DVT), while also assessing predictors of thrombus clearance, patient experience, and economic impact. Methods A…
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Artikel Jurnal
Is congenital thrombotic thrombocytopenic purpura a risk factor for ischemic osteonecrosis of the hip joint (Legg-Calvé-Perthes disease)?
Abstract Weise et al. reported on a 41-year-old patient previously diagnosed with congenital thrombotic thrombocytopenic purpura undergoing total hip replacement surgery for Perthes disease. This case raises the question whether ischemic osteonecrosis of the femoral head is another so far…
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Artikel Jurnal
Thromboembolic events associated with antiangiogenic monoclonal antibodies: a disproportionality analysis from FDA adverse event reporting system (FAERS) database
Abstract Background Antiangiogenic monoclonal antibodies are increasingly used for various cancers. Although studies have reported thromboembolic events (TEEs) in patients receiving antiangiogenic monoclonal antibodies (mAbs), a comprehensive analysis of various thromboembolic events and their…
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Artikel Jurnal
4G/5G polymorphism and plasma levels of plasminogen activator inhibitor-1 in essential thrombocythemia patients with driver mutational status
Abstract Essential thrombocythemia (ET) is a kind of myeloproliferative neoplasms. Thrombosis is one of the common symptoms, however, the incidence of thrombosis in ET with JAK2, CALR, MPL gene mutations varies greatly, and the underlying mechanism is unclear. The clinical data of 155 consecutive…
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Artikel Jurnal
An integrative analysis of genetic factors reveals dysregulation of cytokines, immune signaling, and T cell activity as the underlying immune mechanisms in autoimmune immune thrombocytopenia
Abstract Background Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by immune-mediated platelet destruction, leading to an abnormally reduced platelet count. While numerous susceptibility genomic loci have been identified, the genetic mechanisms and pathways driving ITP remain…
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Artikel Jurnal
Echinocandins and coagulation dysfunction events
Abstract Despite the recently reported real-world evidence of the signals between echinocandins and coagulation dysfunction events, there are some concerns that may impact the robustness and implications of these findings. For the study design, combining hypercoagulation and hypocoagulation into a…
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Artikel Jurnal
Balloon-assisted radial release for retrieval of a surgically suture-fixed inferior vena cava filter: a case report
Abstract Background The retrieval of an inferior vena cava (IVC) filter is essential for preventing complications related to the filter. Surgically induced suture fixation is an extremely rare cause of filter entrapment and presents unique technical challenges. This case describes a…
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Artikel Jurnal
Association between intermittent pneumatic compression use and deep vein thrombosis in hospitalized adult medical patients: a retrospective single-center case–cohort study in Japan
Abstract Background Clinical practice guidelines of venous thromboembolism prophylaxis for acutely ill hospitalized medical patients recommend intermittent pneumatic compression (IPC) devices as a mechanical thromboprophylaxis option for those at high risk for bleeding. However, supporting evidence…
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Artikel Jurnal
Association between D-dimer difference and risk of postoperative venous thromboembolism in endometrial cancer: a retrospective cohort study
Abstract Objective To investigate the association between D-dimer level changes and venous thromboembolism (VTE) risk in endometrial cancer patients undergoing surgery. Methods This retrospective cohort study included 307 endometrial cancer patients who underwent surgical treatment at Fujian…
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Artikel Jurnal
Case report: Heparin coagulant super-sensitivity during leech therapy
Abstract Background Leech therapy is used in diverse ways in the medical field, such as for flap salvation and for treatment of osteoarthritis. While bleeding is a recognized adverse effect, severe coagulopathy is rare and underreported, especially when compounded by concurrent anticoagulant use…
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Artikel Jurnal
Hydroxyurea-associated digital gangrene: a case report and narrative review of reported cases and emerging pathophysiology
Abstract Background Hydroxyurea (HU) is a first-line oral cytoreductive agent for selected patients with myeloproliferative neoplasms (MPNs), including polycythemia vera (PV), due to its efficacy and tolerability. Although cutaneous ulceration is a recognized complication of long-term HU exposure…