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Renal Failure
Scopus
ISSN 1525-6049 · Taylor & Francis Group · 2.709 artikel di indeks
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Artikel Jurnal
Nonlinear relationship between stress hyperglycemic ratio and prognosis in patients with cardiac surgery-related kidney injury: a retrospective cohort study
The prognostic role of the stress-induced hyperglycemia ratio (SHR) in patients with acute kidney injury related to cardiac surgery has not been fully explored. This study aims to examine the association between the SHR index and mortality in patients with cardiac surgery-associated acute kidney…
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Artikel Jurnal
Association between the preoperative serum albumin-to-creatinine ratio (sACR) and in-hospital mortality in perioperative patients with chronic kidney disease: a cohort study based on INSPIRE database
Objective: The serum albumin-to-creatinine ratio (sACR) is a potential biomarker for multiple diseases, yet its prognostic role in chronic kidney disease (CKD) patients undergoing surgery remains unexplored. This study aimed to investigate the association between sACR levels and postoperative…
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Artikel Jurnal
The peritoneum in perspective: extracellular vesicles and the future of peritoneal dialysis
Peritoneal dialysis (PD) transforms the peritoneum into a dynamic therapeutic interface, with each exchange offering direct access to molecular and cellular signals from the peritoneal cavity. Among these, extracellular vesicles (EVs) have emerged as stable, information-rich messengers reflecting…
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Artikel Jurnal
Protective effects of adenosine triphosphate, thiamin, thiamin pyrophosphate, and their combination against linezolid-induced renal injury and lactic acidosis in rats
Linezolid, an oxazolidinone antibiotic effective against Gram-positive pathogens, may cause nephrotoxicity and lactic acidosis during prolonged therapy. This experimental study investigated the protective effects of adenosine triphosphate (ATP), thiamin, thiamin pyrophosphate (TPP), and their…
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Artikel Jurnal
Early posttransplant rituximab use in kidney transplant recipients with preexisting donor-specific antibodies
The presence of pretransplant anti-human leukocyte antigen (HLA) donor-specific antibodies (DSAs) is still a significant barrier to successful kidney transplantation, as it increases the risk of rejection and graft failure. Rituximab (anti-CD20 antibody) has been administered in hopes of…
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Artikel Jurnal
A tri-scale in silico framework integrating pharmacovigilance and mechanistic modeling suggests tepotinib-associated acute kidney injury risk
Proactive safety evaluation of molecularly targeted therapies requires generalizable frameworks that integrate real-world evidence with mechanistic insights. As a case in point, tepotinib, a mesenchymal-epithelial transition (MET) inhibitor for non-small cell lung cancer, has a known pulmonary…
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Artikel Jurnal
Splicing of fibronectin gene contribute to the aneurysmal dilatation of arteriovenous fistula
Patients with end-stage renal disease often require arteriovenous fistula (AVF) creation for hemodialysis. However, nearly 40% of patients develop aneurysmal dilatation of AVF (AVFA) after surgery, which can lead to prolonged bleeding at puncture sites, increased infection risk, and even potential…
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Artikel Jurnal
Long-term renal outcomes of patients with biopsy-proven malignant hypertension-associated renal thrombotic microangiopathy who are dialysis-independent at baseline
This observational cohort study aimed to identify factors influencing long-term renal outcomes in 170 patients with biopsy-proven malignant hypertension (MHT)–associated renal thrombotic microangiopathy (TMA) who were dialysis-independent at baseline, recruited between 2008 and 2023. Over a median…
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Artikel Jurnal
Long-term real-world outcomes of rituximab in primary membranous nephropathy: a 154-patient cohort study from China
To investigate the long-term efficacy and safety of rituximab (RTX) in treating patients with primary membranous nephropathy (pMN), a total of 154 patients with pMN receiving RTX treatment were retrospectively enrolled in this study. The study included 92 patients who received RTX as an initial…
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Artikel Jurnal
Association of nephrolithiasis history with adverse outcomes in cardiovascular–kidney–metabolic syndrome
Cardiovascular-kidney-metabolic (CKM) syndrome significantly impacts a large segment of the general population. The risk factors associated with progression of CKM syndrome as well as all-cause mortality warrant further investigations. In this study, we aimed to assess whether nephrolithiasis…
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Artikel Jurnal
Biochemical phenotypes of acute kidney injury and their association with major adverse kidney events
Acute kidney injury (AKI) is a heterogeneous syndrome in which conventional stratification based on serum creatinine and urine output may fail to capture the full spectrum of underlying metabolic disturbances. In a retrospective cohort study of hospitalized adults with AKI admitted to Hospital…
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Artikel Jurnal
Riboflavin intake and kidney health: population evidence and mechanistic insights from NHANES and molecular docking analyses
Chronic kidney disease (CKD) constitutes a significant global public health challenge, with emerging evidence suggesting that riboflavin may confer renoprotective effects. However, the association between dietary riboflavin intake and CKD risk remains inadequately elucidated. To investigate this…
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Artikel Jurnal
Single-cell transcriptomics and machine-learning reveal M1 macrophage-driven progression from minimal change disease to focal segmental glomerulosclerosis
Minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS) are two key nephrotic syndrome types with significant clinical implications. MCD predominantly affects children, while FSGS is more common in adults, often leading to irreversible kidney dysfunction. Despite shared features…
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Artikel Jurnal
Efficacy and safety of prolyl hydroxylase inhibitors for anemia in chronic kidney disease: a network meta-analysis
This Bayesian network meta-analysis evaluated the efficacy and safety of six prolyl hydroxylase inhibitors (PHIs) versus erythropoiesis-stimulating agents (ESAs) or placebo for chronic kidney disease (CKD) anemia. Electronic databases were searched through 1 May 2025. The prespecified primary…
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Artikel Jurnal
Flow-driven left ventricular remodelling in long-term haemodialysis: a multicenter model of arteriovenous access-induced cardiac load
Background Arteriovenous (AV) access, an essential component of dialysis treatment, has been implicated in the development of cardiovascular abnormalities. However, whether AV access blood flow and the duration of exposure to this flow, as represented by the dialysis vintage, have independent or…
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Artikel Jurnal
Cardiorenal protective effects of glucagon-like peptide-1 receptor agonists in chronic kidney disease: a systematic review and meta-analysis
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are widely used in patients with chronic kidney disease (CKD), but existing evidence regarding their efficacy and safety remains inconsistent. To evaluate the cardiorenal outcomes and adverse effects of GLP-1 RAs in this population, we conducted…
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Artikel Jurnal
Impact of dual antiplatelet therapy duration after percutaneous coronary intervention on outcomes in acute coronary syndrome patients with and without chronic kidney disease: a nationwide cohort study
Dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) reduces thrombotic risk in acute coronary syndrome (ACS) but may increase bleeding, especially in chronic kidney disease (CKD). This study evaluated the impact of different DAPT durations on cardiovascular and bleeding…
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Artikel Jurnal
Vitamin D deficiency, multimorbidity, and mortality in stage 2 cardiovascular-kidney-metabolic (CKM) Syndrome: evidence from the NHANES 2001–2018 cohort
This study aimed to compare mortality risks among patients with stage 2 cardiovascular-kidney-metabolic syndrome (CKM) across different multimorbidity states. Furthermore, it investigated whether sufficient serum vitamin D (≥75 nmol/L) modulates the association between multimorbidity and mortality…
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Artikel Jurnal
Cardiorespiratory fitness and left ventricular recovery after kidney transplantation: evidence, gaps, and future directions
Background Despite improved survival following kidney transplantation, cardiovascular disease (CVD) remains a leading cause of mortality in kidney transplant recipients (KTRs). This risk is driven by complex traditional and nontraditional mechanisms contributing to uremic cardiomyopathy…
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