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COPD
Scopus
ISSN 1541-2563 · Taylor & Francis Group · 203 artikel di indeks
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Artikel Jurnal
The Effect of Anion Inhalation in a Mouse Model of Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease
Background Oxidative/anti-oxidative stress unbalance is one of the mechanisms of chronic obstructive pulmonary disease (COPD). Anion has been shown to be effective to eliminate reactive oxygen species, yet it is unknown if inhalation of anion (IA) can be beneficial for COPD intervention.Methods…
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Artikel Jurnal
Impact of Comorbid Interstitial Lung Abnormalities on Acute Exacerbations of COPD: A Hospital-Based Retrospective Cohort Study
Objective To assess the influence of comorbid interstitial lung abnormalities (ILA), lung fibrosis (LF), and interstitial lung disease (ILD) on clinical characteristics and in-hospital outcomes in acute exacerbations of chronic obstructive pulmonary disease (AECOPD).Methods In this retrospective…
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Artikel Jurnal
Ferroptosis-Related Signature Genes and Immune Landscape in Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is characterized by heightened inflammation and immune dysregulation, yet its underlying molecular mechanisms remain incompletely understood. This study aimed to identify ferroptosis-associated signature genes in AECOPD and to…
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Artikel Jurnal
Integrating Lung Function Parameters into the Framingham Score for Improved CVD Risk Prediction in COPD: A Cross-Sectional Study Based on NHANES 2007–2012
Individuals with Chronic Obstructive Pulmonary Disease (COPD) constitute a high-risk population for Cardiovascular Disease (CVD). There is growing concern that standard risk assessment tools like the Framingham Risk Score (FRS) may be subject to underestimation of CVD risk in COPD patients…
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Artikel Jurnal
Initial Treatment of COPD with LABA-LAMA Versus LAMA: Real-World Comparative Effectiveness and Safety
Respiratory societies now advocate for long-acting beta2-agonist (LABA) and long-acting muscarinic antagonist (LAMA) combinations (LABA-LAMA) as initial pharmacological treatment of COPD patients with multiple exacerbations or significant symptoms. However, the evidence comes from trials involving…
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Artikel Jurnal
Respiratory-Endocrinology Multidisciplinary Co-Management Pathway in Hospitalized Patients with ECOPD and Diabetes: A Randomized Controlled Trial
Exacerbation of chronic obstructive pulmonary disease (ECOPD) frequently coexists with diabetes mellitus, creating competing priorities for respiratory stabilization and safe inpatient glycemic control. Evidence for an integrated, respiratory-endocrinology co-management pathway in this population…
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Artikel Jurnal
Upregulation of LncRNA MIR31HG in COPD Correlates with Disease Severity and Facilitates Inflammation via miR-342-3p
Background Long non-coding RNA MIR31HG (lncRNA MIR31HG) plays a well-defined role in tumor progression. However, its roles in chronic obstructive pulmonary disease (COPD) progression remain elusive. This study aimed to investigate the expression level and the physiological role of lncRNA MIR31HG in…
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Artikel Jurnal
Airway Mucus Occlusions in Ex-Smokers with and Without COPD
In patients with moderate-to-severe COPD, airway mucus-occlusions correlate with airflow limitation, exacerbation and mortality-risk. However, the clinical relevance of mucus-plugs in milder COPD is not well-understood. We evaluated pulmonary function, six-minute-walk-distance (6MWD), emphysema and…
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Artikel Jurnal
AVAPS Versus BiPAP in Acute Hypercapnic Respiratory Failure: A Systematic Review and Meta-Analysis
Noninvasive ventilation (NIV) is increasingly used in acute and chronic hypercapnic respiratory failure (HRF), with BiPAP traditionally considered the standard mode. Average volume assured pressure support (AVAPS) adjusts inspiratory pressure to maintain target tidal volume, potentially improving…
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Artikel Jurnal
Symptom Improvement with BDP/FF/G Fixed Triple Inhalation Powder in Moderate to Severe COPD Patients Uncontrolled with Dual Therapies: A Non-Interventional, Open-Label, Single-Arm, Prospective Study (RESPONSE Slovenia)
People living with COPD are frequently inadequately treated due to underdiagnosis or misdiagnosis. The aim of this study was to evaluate the real-world performance of the beclomethasone dipropionate/formoterol fumarate/glycopyrronium (BDP/FF/G) fixed triple combination formulated in a dry powder…
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Artikel Jurnal
Barriers and Facilitators to Practitioner Identification and Treatment of Patients with Chronic Obstructive Pulmonary Disease (COPD): A Systematic Search and Narrative Synthesis
Chronic Obstructive Pulmonary Disease (COPD) remains underdiagnosed and undertreated despite the availability of clinical guidelines. Variability in care delivery suggests that factors beyond clinical knowledge influence how care is implemented in practice. Understanding the barriers and…
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Artikel Jurnal
The Associations Between Socioeconomic Deprivation, Social Isolation and Sedentary Time in COPD: A UK Biobank Study
Background People with COPD are more likely to be sedentary, a behaviour associated with reduced life expectancy. COPD is also associated with social isolation and socioeconomic deprivation. Therefore, this study aimed to examine the relationship between these determinants and sedentary…
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Artikel Jurnal
Single-slice Functional Lung MRI During Metronome-Paced Tachypnea Detects Changes in Regional Ventilation Dynamics After a Single Dose of Dual Bronchodilator Treatment in COPD
Dual long-acting bronchodilators are a standard treatment in chronic obstructive pulmonary disease (COPD), aimed at alleviating dyspnea, improving exercise tolerance, and preventing exacerbations. Metronome-paced tachypnea (MPT) offers a feasible alternative to exercise testing for the evaluation…