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Genes & Nutrition
Scopus
ISSN 1555-8932 · BMC · 72 artikel di indeks
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Artikel Jurnal
Current knowledge and interest of French Canadians regarding nutrigenetics
Abstract Objective The purpose of this study was to draw a global portrait of the current knowledge and interest regarding nutrigenetics in a population of French Canadians from the province of Quebec (Canada). Methods A total of 2238 residents from the province of Quebec, Canada, were recruited…
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High-throughput sequencing of small RNAs and analysis of differentially expressed microRNAs associated with high-fat diet-induced hepatic insulin resistance in mice
Abstract Background Hepatic insulin resistance (IR) plays a crucial role in the development of many metabolic diseases, such as type 2 diabetes. MicroRNAs (miRNAs) are involved in the pathogenesis of IR and related diseases; however, studies of miRNAs in hepatic IR are limited. Method In this…
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Artikel Jurnal
Gastric infusion of short-chain fatty acids can improve intestinal barrier function in weaned piglets
Abstract Background The present study was conducted to investigate the effects of gastric infusion of short-chain fatty acids (SCFA) on gut barrier function in a pig model. In this study, 21 DLY barrows with an average initial body weight of (8.31 ± 0.72) kg were randomly allotted into three…
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Transcriptional response of cultured porcine intestinal epithelial cells to micro algae extracts in the presence and absence of enterotoxigenic Escherichia coli
Abstract Background Micro algae’s are worldwide considered as an alternative source of proteins in diets for animals and humans. Micro algae also produce an array of biological active substances with potential to induce beneficial and health promoting effects. To better understand the mode of…
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Associations between olfactory pathway gene methylation marks, obesity features and dietary intakes
Abstract Background Olfaction is an important sense influencing food preferences, appetite, and eating behaviors. This hypothesis-driven study aimed to assess associations between olfactory pathway gene methylation signatures, obesity features, and dietary intakes. Methods A nutriepigenomic…
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Circulating microRNAs are associated with early childhood obesity: results of the I.Family Study
Abstract Background Nearly 10 years ago, the World Health Organization reported the increasing prevalence of overweight and obesity worldwide as a challenge for public health due to the associated adverse consequences. Epidemiological studies established a firm relationship between an elevated body…
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Biomarkers of tuber intake
Abstract Tubers are important crops as well as staple foods in human nutrition. Among tubers, the potato in particular has been investigated for its health effects. However, except for its contribution to energy and effects related to resistant starch, the role of potatoes and other tubers in human…
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Biomarkers of food intake for nuts and vegetable oils: an extensive literature search
Abstract Nuts and vegetable oils are important sources of fat and of a wide variety of micronutrients and phytochemicals. Following their intake, several of their constituents, as well as their derived metabolites, are found in blood circulation and in urine. As a consequence, these could be used…
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Is C. elegans a suitable model for nutritional science?
Abstract The suitability of C. elegans as a model for the question of nutritional science is a controversial topic. The discussion makes clear that C. elegans is its own best model for revealing, via genetic approaches, biological principles of nutritional behavior, and the biochemical function of…
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Differences in peripheral blood mononuclear cell gene expression and triglyceride composition in lipoprotein subclasses in plasma triglyceride responders and non-responders to omega-3 supplementation
Abstract Background Intake of the marine omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) reduces fasting triglyceride (TG) levels and may thereby lower cardiovascular disease risk. However, there are large inter-individual differences in the TG-lowering effect of…
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Artikel Jurnal
Drosophila melanogaster in nutrition research—the importance of standardizing experimental diets
Abstract The fruit fly Drosophila melanogaster has been increasingly recognized as an important model organism in nutrition research. In order to conduct nutritional studies in fruit flies, special attention should be given to the composition of the experimental diets. Besides complex diets, which…
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Artikel Jurnal
Correction to: Plasma fatty acid levels and gene expression related to lipid metabolism in peripheral blood mononuclear cells: a cross-sectional study in healthy subjects
Unfortunately, after publication of this article [1], it was noticed that some corrections to Table 2 were not carried out. The corrected Table 2 can be seen below and the original article has also been updated to reflect this.
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Genetic polymorphisms of antioxidant enzymes CAT and SOD affect the outcome of clinical, biochemical, and anthropometric variables in people with obesity under a dietary intervention
Abstract Background Genetic polymorphisms of antioxidant enzymes CAT, GPX, and SOD are involved in the etiology of obesity and its principal comorbidities. The aim of the present study was to analyze the effect of aforementioned SNPs over the output of several variables in people with obesity after…
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Artikel Jurnal
FTO genotype, dietary protein intake, and body weight in a multiethnic population of young adults: a cross-sectional study
Abstract Background Variation in the fat mass and obesity-associated gene (FTO) has been associated with susceptibility to obesity, but the association appears to be modified by diet. We investigated whether dietary protein intake modifies the association between FTO variant rs1558902 and body mass…
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Betaine reduces β-amyloid-induced paralysis through activation of cystathionine-β-synthase in an Alzheimer model of Caenorhabditis elegans
Abstract Background The neurodegenerative disorder Alzheimer’s disease is caused by the accumulation of toxic aggregates of β-amyloid in the human brain. On the one hand, hyperhomocysteinemia has been shown to be a risk factor for cognitive decline in Alzheimer’s disease. On the other hand, betaine…
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Effect of β-hydroxy-β-methylbutyrate on miRNA expression in differentiating equine satellite cells exposed to hydrogen peroxide
Abstract Background Skeletal muscle injury activates satellite cells to initiate processes of proliferation, differentiation, and hypertrophy in order to regenerate muscle fibers. The number of microRNAs and their target genes are engaged in satellite cell activation. β-Hydroxy-β-methylbutyrate…
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Artikel Jurnal
Correction to: Biomarkers of legume intake in human intervention and observational studies: a systematic review
Following publication of the original article [1], the authors reported a spelling error of the third author’s name, Mar Garcia Aloy.
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Exploring the cellular network of metabolic flexibility in the adipose tissue
Abstract Background Metabolic flexibility is the ability of cells to change substrates for energy production based on the nutrient availability and energy requirement. It has been shown that metabolic flexibility is impaired in obesity and chronic diseases such as type 2 diabetes mellitus…
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Genetic risk score for adult body mass index associations with childhood and adolescent weight gain in an African population
Abstract Background Ninety-seven independent single nucleotide polymorphisms (SNPs) are robustly associated with adult body mass index (BMI kg/m2) in Caucasian populations. The relevance of such variants in African populations at different stages of the life course (such as childhood) is unclear…
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Dietary and genetic risk scores and incidence of type 2 diabetes
Abstract Background Both lifestyle and genetic predisposition determine the development of type 2 diabetes (T2D), and studies have indicated interactions between specific dietary components and individual genetic variants. However, it is unclear whether the importance of overall dietary habits…