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Journal of Materials Science: Materials in Medicine
Scopus
ISSN 1573-4838 · Springer · 533 artikel di indeks
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Artikel Jurnal
M1 macrophage membrane-engineered PLGA nanoparticles reprogram M2 tumor-associated macrophages to enhance anti-tumor immunity in breast cancer
Abstract Nanoparticles (NPs) are used as a suitable delivery system in cancer immunotherapy. Coating NPs with cell membranes can improve their therapeutic efficacy. Tumor-associated macrophages (TAMs) with a dominant phenotype of M2 and anti-inflammatory properties are found within the tumor…
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Artikel Jurnal
A pH-responsive mesoporous Zn-MOF nanocarrier for efficient cisplatin delivery and inhibition of A549 cancer cells
Abstract Mesoporous metal-organic frameworks (MOFs) have the advantages of high specific surface area, tunable pore size, and favorable biocompatibility, making them promising candidates for drug delivery in cancer therapy. In this study, a series of mesoporous zinc-based MOF, constructed using…
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Artikel Jurnal
Characterization of soft tissue-mimicking materials for ultrasound training phantoms
Abstract Tissue-mimicking materials are essential for developing realistic ultrasound phantoms in medical training and device calibration. This study systematically evaluates the acoustic and physical properties of 15 materials, including gelatin-based formulations, synthetic gels, and rubbers, to…
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Artikel Jurnal
Sustainable development of ZnO nanoparticles and nanocellulose-modified CPE for electrochemical sensing of tinidazole
Abstract The detection of tinidazole (TIZ) in environmental and pharmaceutical samples remains constrained by conventional electrochemical sensors, which often rely on energy-intensive synthesis routes and toxic modifiers, undermining their sustainability. To bridge this gap, this study introduces…
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Artikel Jurnal
A self-healing hydrogel based on modified chitosan and sodium alginate oxide reinforced with hydrophilic nanomaterials for wound dressing applications
Abstract N-carboxyethyl chitosan (CECS) and sodium alginate oxide (SAO) are two biomaterials extensively used in tissue engineering, particularly in wound dressing (WD) applications. Nonetheless, these materials exhibit certain limitations such as inadequate physicomechanical properties, limited…
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Artikel Jurnal
Effect of niosome formation with chitosan coating on the stability and absorption of orally administered vesicular ursolic acid
Abstract Niosomes are known to improve the bioavailability of drugs. However, niosomes have drawbacks related to stability and absorption in the gastrointestinal tract. Chitosan coating on niosomes can increase their stability in gastrointestinal fluid and absorption after oral administration. This…
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Artikel Jurnal
Application of PLCL as a biodegradable polymer in biomedical engineering
Abstract Poly (L-lactide-co-ε-caprolactone) (PLCL) is a novel polymer that has attracted considerable attention in the biomedical field due to its exceptional biocompatibility. However, a comprehensive and systematic summary of its diverse applications remains lacking. To address this gap, the…
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Artikel Jurnal
Investigation and development of bilayer scaffolds: ZnONPs-loaded poly (vinyl alcohol) incorporated with Platostoma palustre aqueous extract and sponge collagen derived from fish skin
Abstract This study introduces the design of two bilayer scaffolds that offer safety and show potential for biomedical applications, especially for wound healing in the skin or oral cavity. Each scaffold is composed of a collagen sponge layer derived from warm-water fish skin (seabass and tilapia)…
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Artikel Jurnal
Fabrication and characterization of biodegradable Zn-Ni spinel ferrite/ β-TCP composite ceramics exhibiting enhanced cell colonization
Abstract Via a solid-state reaction route, magnetic composites of chicken eggshell-derived β-tricalcium phosphate (β-TCP, referred to as TCP in the composite system) and zinc-nickel spinel ferrite (ZNF; Zn x Ni1‒x Fe2O4, x = 0.2, 0.4, 0.6, or 0.8) were successfully fabricated. Discs were prepared…
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Artikel Jurnal
Enhancing bone repair ability of 3D-printed PLLA scaffolds via N-methyl-2-pyrrolidone etching
Abstract The development of bone repair scaffolds has long been a research hotspot in tissue engineering. Owing to its unique capability for personalized customization of scaffold geometry and microstructure, 3D printing technology has been extensively adopted for fabricating bone repair scaffolds…
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Artikel Jurnal
Efficacy and safety of a novel ab interno supraciliary HA-Mg biodegradable glaucoma drainage plate implantation in rabbit eyes
Abstract The uveoscleral outflow pathway is one of the important pathways for aqueous humor outflow. Implanting ab interno glaucoma drainage devices through this pathway does not require conjunctival filtering bleb formation, thereby avoiding bleb-related complications. However, permanent drainage…
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Artikel Jurnal
Exosome-loaded hydrogel systems for spinal cord injury repair: mechanisms, advancements, and future directions
Abstract Despite ongoing research efforts, spinal cord injury (SCI) remains one of the most disabling neurological disorders where current therapies provide limited solutions that mostly address symptoms rather than true regeneration. The latest research indicates that exosome-loaded hydrogel…
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Artikel Jurnal
Magnetic nanoparticles as promising materials for the future of medicine
Abstract Over the past few decades, magnetic nanoparticles (MNPs) have emerged as a focal point of research due to their versatility and diverse applications across biomedical and technological domains. The rapid advancement in nanotechnology has enabled MNPs to be utilized in drug delivery…
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Artikel Jurnal
Smart nanoparticle delivery systems for curcumin: a targeted strategy to enhance anticancer efficacy and bioavailability
Abstract Curcumin, a natural polyphenol derived from Curcuma longa, exhibits potent multimodal anticancer activity by modulating critical oncogenic pathways (e.g., NF-κB, STAT3, PI3K/Akt/mTOR), inducing apoptosis, suppressing angiogenesis, and reversing multidrug resistance (MDR). However, its…
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Artikel Jurnal
Study on the antioxidant and anti-inflammatory properties of different morphologies of ceria nanoenzymes with multi enzyme mimetic activity
Abstract Cerium dioxide (CeO₂) nanozymes are capable of mimicking the activities of superoxide dismutase (SOD) and catalase (CAT), thereby facilitating the scavenging of reactive oxygen species (ROS). This study aims to synthesize CeO₂ nanozymes with different morphologies by controlling reaction…
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Artikel Jurnal
Fullerene C60 in dental materials: a comprehensive review of carbon nanotechnology applications and future prospects
Abstract Teeth and dental materials are very noteworthy because of their important role in digestion and facial beauty. It is necessary to develop dental materials with suitable physical, chemical and biological properties to improve the quality and beauty of teeth. Fullerene, as a spherical…
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Artikel Jurnal
Multifunctional drug delivery of nanofibrous iron-polyphenolic nanochelates improved photothermal therapy against colorectal cancer via ferroptosis
Abstract Ferroptosis is a novel anticancer therapeutic approach that effectively circumvents the apoptotic cell death mechanism. Nonetheless, enhancing the catalytic effectiveness of the Fe2+-mediated Fenton reaction and effectively inducing ferroptosis present significant challenges. In this…
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Artikel Jurnal
Effect of thin porous ceramic coatings on implant stability: a comparative study of GB14 and β-TCP with and without Cu
Abstract The present study investigates the effect of thin porous ceramic coatings on implant stability, focusing on two materials: a calcium alkali orthophosphate (GB14, Ca2KNa(PO4)2) and β-tricalcium phosphate (β-TCP), with and without copper (Cu) incorporation. The coatings were applied to…
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Artikel Jurnal
Aloe vera integrated ZnO/SWCNT/Ag nanocomposites for accelerated wound repair and scar reduction
Abstract For centuries, natural extracts such as Aloe vera have been used in wound care due to their soothing, anti-inflammatory, and healing properties. However, their clinical efficacy can be limited by instability, low bioavailability, and restricted antimicrobial potency. Nanotechnology offers…
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Artikel Jurnal
Chitosan-based nano-encapsulation enhances the anti-diabetic efficacy of Eremina desertorum extract by ameliorating hyperglycemia, oxidative stress, and inflammation in diabetic rats
Abstract This study developed a novel Eremina desertorum snail extract (Ere extract) loaded-chitosan nanoparticles (Ere-CS NPs) to enhance the anti-diabetic efficacy of Eremina desertorum snail extract. The nanoparticles, synthesized via ionic gelation, were spherical (~80 nm) and exhibited storage…