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Intestinal Research
Scopus
ISSN 1598-9100 · Korean Association for the Study of Intestinal Diseases · 804 artikel di indeks
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Artikel Jurnal Teks lengkap
Correction: Gut, bone, and muscle: the triad of osteosarcopenia in inflammatory bowel disease
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Artikel Jurnal Teks lengkap
Decoding genetic divergence: TPMT and NUDT15 polymorphisms in north India mirror Caucasian ancestry
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Artikel Jurnal Teks lengkap
Peroxisome proliferator-activated receptors in inflammatory bowel disease: linking immunometabolism, lipid signaling, and therapeutic potential
Inflammatory bowel disease (IBD), encompassing Crohn’s disease (CD) and ulcerative colitis, is a chronic condition marked by immune dysregulation, genetic predisposition, and metabolic disturbances. Emerging evidence highlights the role of lipid metabolism and peroxisome proliferator-activated…
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Does the size of the cold snare affect the outcome of cold snare polypectomy in the colon? A KASID prospective multicenter study
Background/Aims Cold snare polypectomy (CSP) is recommended for colorectal polyps 8 mm as an independent predictor of complete resection (odds ratio, 3.89; 95% confidence interval, 1.15–13.21; P= 0.029); snare size was not significantly associated with CRR (P= 0.519). Conclusions CSP using either a…
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Real-world use of biologics during the first year of treatment for newly diagnosed Crohn’s disease in Japan: a claims analysis from 2010 to 2021
Background/Aims Crohn’s disease (CD) leads to bowel damage and disability if suboptimally treated. We investigated firstyear treatment decisions and real-world use of biologics in patients with CD in Japan. Methods In this retrospective observational study (2010–2021) from the JMDC claims database…
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Burden of inflammatory bowel disease in India: analysis of the Global Burden of Disease study from 1990 to 2019
Background/Aims Inflammatory bowel disease (IBD) is increasing across the globe, more so in populous countries like India. We aimed to study the disease burden and epidemiological trends of IBD in India and look closer into the disease pattern across the country from 1990 to 2019. Methods The…
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Characteristics and long-term outcomes of children with perianal Crohn’s disease
Background/Aims The incidence of perianal lesions (PL) in children with Crohn’s disease (CD) is higher in East Asia than in Western countries. Early intervention for PL is essential to prevent sphincter dysfunction and ostomy placement. In this study, we aimed to investigate the clinical features…
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Optimal use and cycling strategies of Janus kinase inhibitors in ulcerative colitis: current evidence and clinical implications from the KASID Guidelines Task Force Team
Janus kinase (JAK) inhibitors are an important treatment option for ulcerative colitis, providing rapid onset of action, oral administration, and efficacy even after biologic failure. The 3 approved agents—tofacitinib, filgotinib, and upadacitinib—differ in JAK isoform selectivity, leading to…
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Clinical characteristics of patients with difficult-to-treat ulcerative colitis: a nested case-control study using a Japanese claims database
Background/Aims Despite the advent of advanced therapies, cases of so-called “difficult-to-treat” (D2T) ulcerative colitis (UC) persist. This study aims to clarify the epidemiological and clinical characteristics of patients with D2T UC. Methods We conducted a nested case-control study using the…
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KASID and journal: a central academic hub for research of intestinal diseases in the Asia-Pacific region
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Process of empowerment in mothers of children with very-early-onset inflammatory bowel disease: a qualitative study
Background/Aims Mothers of children with very-early-onset inflammatory bowel disease (VEO-IBD) face unique challenges; however, these challenges and their consequences have not been well described. This study clarified the experiences and processes of empowerment of mothers of children with…
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Comparison between endoscopic resection and transanal surgery for treatment of rectal tumors: a systematic review and meta‑analysis
Background/Aims Both endoscopic resection (ER) and transanal surgery (TAS) are minimally invasive treatment options that allow organ preservation in early rectal tumors. We conducted a meta-analysis to compare treatment outcomes between the 2 treatments. Methods We searched all relevant studies…
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Ustekinumab-induced Henoch-Schönlein purpura in Crohn’s disease: a case report and literature review
Crohn’s disease is a chronic inflammatory disease of the digestive tract with extraintestinal manifestations, which include skin conditions, arthritis, ocular inflammation, and several autoimmune conditions. Dermatologic manifestations in Crohn’s disease complicate the treatment course and…
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Inflammatory bowel disease in a young female patient with a novel frameshift variant responsive to ustekinumab: a case report
Tumor necrosis factor receptor-associated factor 3 (TRAF3) is an anti-inflammatory molecule that negatively regulates the non-canonical nuclear factor-κB pathway. Although TRAF3 haploinsufficiency (TRAF3 HI) can influence innate and adaptive immune cells, its effect on inflammatory bowel disease…
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Prevalence and outcome of sarcopenia in patients with inflammatory bowel disease: a follow-up study
Background/Aims Sarcopenia is implicated in inflammatory bowel disease (IBD) complications and surgical outcomes. This study aimed to investigate the prevalence and follow-up of sarcopenia in patients with IBD. Methods Consecutive consenting patients with IBD aged > 18 years were included. Patients…
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Comparative short-term efficacy of upadacitinib versus tofacitinib for ulcerative colitis: a 24-week real-world study in Japan
Background/Aims Tofacitinib and upadacitinib are small-molecule compounds that inhibit the Janus kinase pathway for the treatment of refractory ulcerative colitis. Only a few reports have compared the efficacy and safety of these 2 drugs in real-world practice. We aimed to show our real-world…
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Short-term and long-term outcomes of acute severe ulcerative colitis in Taiwan: a multicenter study with pre- and post-biologics comparison
Background/Aims Data from Asia regarding the short-term and long-term outcomes for acute severe ulcerative colitis (ASUC) are limited. We assessed the outcomes of ASUC, identified the risk factors for colectomy, and compared colectomy rates between the pre-biologics and post-biologics eras in…
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The efficacy of ustekinumab in the management of perianal fistulizing Crohn’s disease
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Depressed lesion detected during surveillance colonoscopy in a patient with ulcerative colitis
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Factors affecting 1-year persistence with vedolizumab for ulcerative colitis: a multicenter, retrospective real-world study
Background/Aims The objectives of this real-world study were to determine 1-year persistence with vedolizumab in patients with ulcerative colitis and to evaluate factors contributing to loss of response. Methods In this multicenter, retrospective, observational chart review, patients with…