7.612 hasil
Menampilkan 1–20 · 0,20 detik · RSS
Marine Drugs
Scopus
ISSN 1660-3397 · MDPI AG · 7.612 artikel di indeks
-
Artikel Jurnal Teks lengkap
Posidonia oceanica (L.) Delile as a Marine Anti-Inflammatory Modulator of Keratinocyte Inflammatory Responses Relevant to Psoriasis
Skin inflammation is characterized by oxidative stress, excessive keratinocyte activation, and the overproduction of pro-inflammatory cytokines. In a previous study, we demonstrated that the hydroalcoholic extract from Posidonia oceanica leaves (POE) mitigates psoriasis-like skin inflammation in a…
-
Artikel Jurnal Teks lengkap
Synthesis, Biological Evaluation, and Computational Studies of Phenolic N-Acetylglucosamine Glycosides as α-Glucosidase Inhibitors
Type 2 diabetes mellitus (T2DM) is one of the most prevalent chronic metabolic diseases, and inhibition of α-glucosidase activity represents an effective therapeutic strategy. Chitin is the most abundant renewable polysaccharide in the ocean, with its monosaccharide being N-acetylglucosamine (NAG)…
-
Artikel Jurnal Teks lengkap
Anti-Photoaging Effects of a Polysaccharide from Kappaphycus alvarezii In Vitro and In Vivo
The red alga Kappaphycus alvarezii is a rich source of polysaccharides, but their high molecular weight limits skin permeability and bioavailability. To address this, we employed a free-radical degradation method to produce a low-molecular-weight polysaccharide, KP-90. Evaluation in UVB-irradiated…
-
Artikel Jurnal Teks lengkap
Marine Microalga Tisochrysis lutea F&M-M36 Modulates Gut Microbiota and Intestinal Cholesterol Transport Gene Expression in Association with Selected Early-Stage Metabolic Alterations Under High-Fat Feeding
Modulation of the gut microbiota represents a promising approach to counteract diet-induced metabolic alterations, with microalgae emerging as potential interventions. Building on our previous in vivo evidence that dietary supplementation with the marine microalga Tisochrysis lutea F&M-M36 (T…
-
Artikel Jurnal Teks lengkap
Synergistic Effects of Light and Salinity on Carotenoid and Biomass Composition of Synechocystis PCC6803 Cultures
Light and salt stress affect the growth of plants and microorganisms, causing photo-oxidative stress. The cyanobacterium Synechocystis is notable for its adaptability to and sustainability in seawater. In this study, the synergistic effects of different light intensities and salt concentrations on…
-
Artikel Jurnal Teks lengkap
Integrative Metabolomics and Systems Pharmacology Reveal PPARγ-Centered Antidiabetic Mechanisms of Caulerpa racemosa and Its Bioactive Compounds
Type 2 diabetes mellitus (T2DM) is a complex metabolic disorder requiring safe, multitarget therapeutic strategies. Marine macroalgae represent an underexplored source of bioactives with pleiotropic metabolic effects. This study investigated the antidiabetic potential of an ultrasound-assisted…
-
Artikel Jurnal Teks lengkap
Phaeodactylum tricornutum as a Chassis: Insights into Its Potential, Challenges, and Perspectives
Phaeodactylum tricornutum is one of the most well-characterized microalgae and serves as a pivotal model diatom in global carbon fixation and the mediation of biogeochemical cycling of essential nutrients. Over the past few decades, the availability of a complete genome assembly, coupled with the…
-
Artikel Jurnal Teks lengkap
Content, Ratio and Productivity of Amphidinols in Wild-Type and Mutagenized Strains of Amphidinium carterae at Different Growth Stages
As agriculture faces increasing pressure to reduce pesticide residues and heavy metal accumulation in soils, marine microalgae are emerging as sustainable sources of biopesticides. Among them, Amphidinium carterae produces amphidinols (AMs), polyketide metabolites with strong antifungal activity…
-
Artikel Jurnal Teks lengkap
Diverse and Bioactive Lactones from the Sri Lankan Mangrove-Derived Fungus Talaromyces sp. SCSIO41445
Three previously uncharacterized lactones, namely penicianstinoid L (1), talaromyketide J (2) and peniciisocoumarin K (3), along with twenty-eight known compounds (4–31), were yielded from the mangrove-derived fungus Talaromyces sp. SCSIO41445, collected from Mangrove Park (NARA), Sri Lanka. Their…
-
Artikel Jurnal Teks lengkap
Harnessing Biogas into High-Value Chemicals: The Role of Algal–Methanotrophic Co-Cultures
The conversion of biogas into high-value chemicals for pharmaceutical, cosmetic, and nutraceutical markets offers an attractive alternative to conventional fossil-based production routes, enabling circular value chains with significant socio-economic impact. This study evaluated the valorization of…
-
Artikel Jurnal Teks lengkap
Enhanced Production of Bioactive Polyunsaturated Fatty Acids and Pigments in Rhodosorus marinus: Optimization of Thermal and Photic Stress Conditions
The marine unicellular red alga Rhodosorus marinus is a promising source of the valuable phycobiliprotein phycoerythrin and essential omega-3 polyunsaturated fatty acids (PUFAs), yet the environmental triggers for their optimal co-production remain to be fully elucidated. This study was conducted…
-
Artikel Jurnal Teks lengkap
Anticancer Effect of Pacificusoside D from the Starfish Solaster pacificus in Combination with 2-Deoxy-D-glucose on Oxidative Phosphorylation in Triple-Negative Breast Cancer Cells MDA-MB-231
Triple-negative breast cancer (TNBC) represents significant therapeutic challenges due to its aggressive behavior, metabolic plasticity, and lack of targeted treatments, prompting investigation of biologically active triterpene glycosides from the starfish Solaster pacificus. This study evaluated…
-
Artikel Jurnal Teks lengkap
Marine Algae-Derived Bioactive Compounds Stabilizing Collagen-Rich Dental Matrices Through Matrix Metalloproteinase Inhibition: A Scoping Review
This scoping review mapped the available evidence on marine algae-derived bioactive compounds, focusing on their biological activities related to collagen stabilization, matrix metalloproteinase (MMP) inhibition, and enamel remineralization in dental hard tissues. Four electronic databases (PubMed…
-
Artikel Jurnal Teks lengkap
Commemorating the Launch of the Section “Marine Toxins”
Marine toxins are natural compounds produced by a variety of marine organisms, including microalgae, bacteria, and macroalgae [...]
-
Artikel Jurnal Teks lengkap
Sulfated Pelvetia siliquosa Polysaccharides Attenuate Pyroptosis via NF-κB Pathway Inhibition Against Calcium Oxalate Stone Formation
Objective: The formation of calcium oxalate (CaOx) kidney stones is accompanied by the pyroptosis of renal epithelial cells. The risk of kidney stone formation can possibly be reduced through pyroptosis inhibition. Methods: Pyroptosis of HK-2 cells induced by 3 µm CaOx monohydrate (COM-3 µm) was…
-
Artikel Jurnal Teks lengkap
Marine-Derived Defenses Against HIV: Emerging Bioactive Molecules from the Seas
Marine ecosystems have yielded a remarkable diversity of bioactive metabolites with relevance for antiviral drug discovery. This article reviews recent advances in marine-derived compounds investigated as anti-HIV agents. Metabolites, such as sulfated polysaccharides, lectins, alkaloids, and…
-
Artikel Jurnal Teks lengkap
From Host-Derived Pressures to the Environmental Anti-Antimicrobial Peptides Resistome: Mechanisms, Reservoirs and Implications for Therapeutic Peptide Design
Antimicrobial peptides (AMPs) are increasingly promoted as alternatives or complements to conventional antibiotics, yet growing evidence demonstrates that resistance to AMPs is neither rare nor incidental. Here, we define the anti-AMP resistome as a coordinated network of genetic, regulatory, and…
-
Artikel Jurnal Teks lengkap
Shellfish as a Source of Bioactive Compounds and Extracts: A Comprehensive Review of Their Anticancer and Antimicrobial Properties
Shellfish are a diverse group of marine animals that play a significant role, as a high proportion of the world’s seafood is produced by shellfish. In general, shellfish contain higher amounts of nutrients that benefit consumer health. In recent years, research has focused on the potential health…
-
Artikel Jurnal Teks lengkap
A Novel Cobalt-Activated Halotolerant α-Amylase with High Specific Activity from Priestia sp. W243 in Kuwait Sabkha for Biotechnological Applications
Sabkhas, hypersaline ecosystems along Kuwait’s coastal zone, are extreme environments that harbor diverse halophilic microorganisms with significant biotechnological potential. Despite this, they remain underexplored, particularly in the context of enzymes that can function under high salinity. The…
-
Artikel Jurnal Teks lengkap
Fucoidan from Fucus vesiculosus Protects Retinal Pigment Epithelium from Lipid-Induced Damage Related to AMD
Fucoidans are natural compounds that exhibit bioactivity against age-related macular degeneration (AMD), the leading cause of central vision loss in industrialized nations. Pathological factors like oxidative stress and lipid peroxidation play vital roles in AMD pathogenesis. Lipid-induced…
Menampilkan maksimal 50 halaman. Persempit pencarian dengan filter untuk hasil yang lebih spesifik.