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Current Urology
Scopus
ISSN 1661-7649 · Wolters Kluwer Health · 334 articles in the index
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Journal Article
Revealing the function and mechanism of piRNA-related genes in bladder cancer through single-cell sequencing and methylation analyses and construction of prognostic features based on consensus clustering
Background:. This study aimed to explore the functions and potential mechanisms of PIWI-interacting RNA–related genes (piRPGs) in bladder cancer (BC) development and to identify potential prognostic genes. Methods:. This study used differential analysis and machine learning techniques to identify…
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Journal Article
Efficacy of early intravesical instillation of hyaluronic acid after transurethral resection of non-muscle-invasive bladder cancers: An open-label, prospective, single-center, randomized, controlled and parallel-group pilot study
Background:. Lower urinary tract symptoms (LUTS) and pain are clinically relevant problems after transurethral resection (TURBT) of nonmuscle-invasive bladder cancer. Although intravesical instillation of hyaluronic acid has already been proven to be a valid treatment for storage LUTS and pain in…
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Journal Article
The role of uropathogenic Escherichia coli biofilms in antibiotic-resistant urinary tract infections: Nanoparticle-based, phage therapy, and quorum-sensing inhibitor approaches
Background:. Urinary tract infections (UTIs) caused by uropathogenic E. coli (UPEC) pose a global health challenge, largely due to UPEC biofilms that drive persistent infections and antibiotic resistance. Materials and methods:. To explore the role of UPEC biofilms in antibiotic-resistant UTIs and…
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Journal Article
A simplified algorithm for management of CP/CPPS and associated entities: A summary table for general urologists
Background:. Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) accounts for 25% urology clinic visits. Due to significant overlap with other conditions, CP/CPPS is frequently misdiagnosed and inadequately managed. Therefore, we provided a simplified diagnostic and treatment approach to…
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Journal Article
Evaluating renal function with intravoxel incoherent motion in a unilateral ureteral obstruction model
Background:. Patients with renal injury are at increased risk of exacerbating kidney damage from contrast-enhanced radiological examinations. Therefore, a noninvasive and sustainable method for assessing renal function without contrast agents is imperative. This study evaluates the effectiveness of…
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Journal Article
Robot-assisted kidney transplantation: Initial experience from a tertiary hospital in China
Abstract. Background. Robot-assisted kidney transplantation (RAKT) has currently become an effective alternative to open kidney transplantation (OKT), which has long been considered the gold standard for kidney transplant surgery. This study aimed to summarize our initial experience with RAKT and…
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Journal Article
Robotic-assisted kidney transplantation: Technical evolution and applications in complex scenarios
Abstract. Robot-assisted kidney transplantation (RAKT) is a new, minimally invasive option for kidney transplantation with great application prospects. This narrative review aimed to outline the developmental history of RAKT, existing technology, and its application in different types of kidney…
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Journal Article
Analysis of overall survival in patients with second primary malignancies following with the first diagnosis of nonmetastatic prostate cancer: A study utilizing the Surveillance, Epidemiology, and End Results database
Abstract. Background. Survival in patients with prostate cancer (PCa) is now significantly prolonged. However, the incidence of secondary primary malignancies (SPMs) has increased during the treatment for PCa, which adversely affects patient survival. This study explored the factors influencing the…
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Journal Article
Causal relationships between plasma metabolites and prostate cancer: A Mendelian randomization study exploring immune and inflammatory mediators
Abstract. Background. Metabolic alterations and inflammatory processes contribute substantially to the pathogenesis of prostate cancer (PCa). This study used Mendelian randomization (MR) to investigate the causal relationships between plasma metabolites and PCa and to identify potential mediators…
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Journal Article
A randomized, triple-blind, placebo-controlled, parallel study of the efficacy of D-mannose for urinary tract infection symptoms in women
Abstract. Background. Urinary tract infections (UTIs) are common infectious disorders affecting 50% of healthy women at least once during their lifetime. Antibiotic treatment for UTIs may increase the prevalence of antimicrobial resistance and side effects, highlighting the need for safe and…
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Journal Article
Molecular mechanisms and classification of castration-resistant prostate cancer: Insights into androgen receptor, cancer stem cells, and neuroendocrine features
Abstract. Castration-resistant prostate cancer (CRPC) is a considerable clinical challenge, driven by complex molecular mechanisms that enable tumors to evade androgen deprivation therapy. This review explores the molecular mechanisms driving CRPC progression, focusing on androgen receptor (AR)…
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Journal Article
Characterization of preoperative patient-reported outcomes in men undergoing benign prostatic hyperplasia surgery
Background:. While the literature on benign prostatic hyperplasia (BPH) often focuses on postoperative patient-reported outcomes (PROs), less attention has been paid to preoperative symptom burden and PROs of men who ultimately undergo surgical treatment. This study provides a detailed descriptive…