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Frontiers in Microbiology
Scopus
ISSN 1664-302X · Frontiers Media S.A. · 40,711 articles in the index
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Journal Article
Can bio-H2 compete with bio-CH4–unequal chances of anaerobic digestion metabolic pathways
Biogas, a mixture of biomethane (bio-CH4) and carbon dioxide (CO2), is the product of methanogenesis, the final stage of anaerobic digestion (AD). Biohydrogen (bio-H2), on the other hand, is produced during the acidogenesis stage through dark fermentation (DF) processes and the transformation of…
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Journal Article
Antimicrobial, anticancer activities and molecular docking of eco-friendly chitosan nanocapsule loaded with biosynthesized titanium nanoparticles by Aspergillus flavus
IntroductionChitosan have been leveraged to create chitosan nanocapsules within a bio-based nanocarrier system, enhancing efficacy and overcoming widespread microbial resistance. To generate chitosan nanocapsules (CNCs) that act as inhibitory agents against pathogenic microbes, this study combined…
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Journal Article
Broadly neutralizing monoclonal antibodies against influenza A viruses: current insights and future directions
Monoclonal antibodies (mAbs) have become attractive tools for both the treatment and prevention of influenza A viruses due to their ability to target several viral components, which confers broad therapeutic potential. Advances in biotechnology, such as hybridoma technology, phage display…
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Journal Article
Resistance to clinically important antibiotics and reduced susceptibility to disinfectants in the pandemic ST398 methicillin-susceptible Staphylococcus aureus from Austria
IntroductionStaphylococcus aureus is a frequent coloniser and pathogen of humans and animals. The prevalence of human-associated methicillin-susceptible Staphylococcus aureus (MSSA) belonging to the pandemic sequence type (ST) 398 has been increasing globally; however, there are regional…
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Journal Article
Phage enabled precision drug delivery: dual function platforms for therapeutics and genetic cargo transport
The rising concern of antimicrobial resistance, coupled with the continually challenging management of complicated diseases such as cancer, has provided momentum toward precision molecular medicine. This review provides an overview of bacteriophage enabled strategies encompassing both conventional…
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Journal Article
Diversity of DNA viruses in the atmosphere of sub-Antarctic South Georgia
Studying airborne viruses in remote environments like the sub-Antarctic island of South Georgia offers key insights into viral ecology, diversity, and their role in shaping ecosystems through microbial and nutrient interactions. We analyzed airborne viral community composition at two sites in South…
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Journal Article
Metabolic interplay in a synthetic consortium: insights into the mediating role of a minority species
Microbial interactions are pivotal components of Earth's ecosystems, driving essential processes that sustain life, regulate environmental conditions, and ensure ecosystem resilience. A comprehensive understanding of these relationships is imperative for leveraging their potential in environmental…
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Journal Article
Exploring the bacterial diversity and its antibiotic resistance in Kabru Glacier ice cores, Sikkim Himalaya
IntroductionThe Kabru Glacier, located in the Sikkim Himalayan region at an altitude of 7,318–7,412 m above sea level (a.s.l), forms part of the Kanchenjunga range in the Eastern Himalaya. Glaciers in this region are predominantly summer-fed and highly sensitive to climatic fluctuations. Despite…
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Journal Article
CRISPR-Cas9-driven genome editing in Bacillus methanolicus MGA3
Bacillus methanolicus is a thermophilic methylotroph that uses methanol as a sustainable feedstock in biotechnological industry. Here, we developed the CRISPR-Cas9 genome editing tool for B. methanolicus MGA3. This one-plasmid system induces Cas9-mediated double-strand breaks and exploits native…
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Journal Article
Modulation of LPS-associated virulence activity for reduction of periodontal inflammatory burden
BackgroundDysbiotic oral biofilms produce virulence factors, such as lipopolysaccharide (LPS), triggering and sustaining chronic inflammation in periodontal tissues. Modulation of the bioactivity of these products offers a potential novel, adjunctive approach beyond conventional periodontal…
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Journal Article
Diagnostic challenges and treatment approaches for Clostridioides difficile infection in IBD patients
BackgroundClostridioides difficile infection (CDI) poses a major clinical challenge in patients with inflammatory bowel disease (IBD) due to overlapping symptoms, diagnostic complexities, and distinct therapeutic considerations. The interaction between CDI and IBD involves disrupted gut microbiota…
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Journal Article
Whole genome analysis of Bacillus velezensis YNK-FB0059 and its multifunctional plant growth-promoting and biocontrol potential
IntroductionThis study conducted a systematic investigation of Bacillus velezensis YNK-FB0059 from genome to phenotype, aiming to comprehensively elucidate its genetic basis and functional traits through whole-genome sequencing and multi-dimensional in vitro validation experiments, thereby…
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Journal Article
Miso without kōji: nesashi miso ecology driven by spontaneous fermentation with Mucor plumbeus
Nesashi miso is a rare, traditionally fermented soybean paste from Japan, and unlike most misos is produced through spontaneous fermentation without the use of a kōji starter. Here we analyzed a nesashi miso alongside two other misos from the same producer (rice and black soybean) as well as a…
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Journal Article
Chloroflexota in agricultural soils: current knowledge and future research directions
The review organizes current knowledge on the biofunctions, life-history strategies, and environmental responses of Chloroflexota in agricultural soils. Members of this phylum play key roles in carbon, nitrogen, and phosphorus cycling through a high degree of metabolic versatility, including…
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Journal Article
Emergence and characterization of a novel ST627-KL8 carbapenem-resistant Klebsiella pneumoniae lineage associated with ICU transmission in a tertiary hospital, China
IntroductionCarbapenem-resistant Klebsiella pneumoniae (CRKP) poses a serious threat to public health. We characterized a rarely reported ST627-KL8 CRKP lineage associated with intensive care unit (ICU) transmission.MethodsThree isolates (ZJG29565, ZJG30140, and ZJG30146) were obtained from three…
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Journal Article
Molecular mechanisms involved in Plasmodium gametocytogenesis
Malaria, a disease caused by protozoa of the genus Plasmodium, remains a major challenge for global public health. The persistence of disease transmission to the mosquito vector depends on the differentiation of asexual blood-stage parasites into gametocytes, a process known as gametocytogenesis…
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Journal Article
Subcellular thiol functional group distribution in Geobacter sulfurreducens determined by Hg LIII-edge EXAFS
Mercury (Hg) is a global environmental concern due to its microbial conversion to methylmercury (MeHg), a potent neurotoxin that bioaccumulates in food webs and poses risks to ecosystems and human health. Thiol functional groups (RSH) play an important role in controlling Hg(II) speciation and…
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Journal Article
Dissecting the role of comS-independent srf expression on multicellular differentiation and competence development in Bacillus subtilis
In its natural soil habitat, B. subtilis regularly encounters fluctuating conditions that require adaptive survival strategies, including the production and secretion of antimicrobial compounds. One such compound, surfactin, play a central role in multicellular differentiation processes such as…
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