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Zhenduanxue lilun yu shijian
Scopus
ISSN 1671-2870 · Editorial Office of Journal of Diagnostics Concepts & Practice · 482 artikel di indeks
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Artikel Jurnal Teks lengkap
Fungal resistance surveillance report in East China in 2025
Objective This study aims to monitor the antifungal susceptibility of clinically isolated fungi in East China in 2025, thereby providing a reference for clinical diagnosis and treatment. Methods A retrospective analysis was conducted on clinical fungi collected by the East China Invasive Fungal…
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Interpretation of 2025 Expert Consensus on Clinical Testing Pathway For Infectious Fever
To establish a scientific, standardized, and operable clinical laboratory pathway for infectious fever, and to address current problems such as blind selection of testing items, inappropriate testing timing, and inadequate multidisciplinary collaboration in clinical testing for infectious fever…
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Incidence and mortality analysis of lung cancer in Shanghai from 2002 to 2019
Objective This study aims to analyze the incidence and mortality of lung cancer in Shanghai from 2002 to 2019 and their variation trends. Methods Data on lung cancer incidence and mortality in Shanghai from 2002 to 2019 were obtained from the population-based cancer registry management system and…
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Research progress on antibacterial strategies against methicillin-resistant Staphylococcus aureus
The in-hospital mortality rate of methicillin-resistant Staphylococcus aureus (MRSA) can reach 20%-30%, which has attracted global attention. However, the clinical treatment options for MRSA infections are still very limited. The drug resistance mechanisms of MRSA can be divided into intrinsic and…
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Risk factors for occurrence and poor prognosis of neonatal candidemia
Objective This study aims to analyze the risk factors for the occurrence of neonatal candidemia and those associated with poor prognosis, thereby providing evidence for clinical diagnosis and treatment. Methods This retrospective study enrolled consecutive 57 cases of neonatal candidemia diagnosed…
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A case report of pseudohypoparathyroidism type 1b caused by noval mutation of STX16
Pseudohypoparathyroidism (PHP) is a group of clinical syndromes caused by peripheral target tissue resistance to parathyroid hormone (PTH). Its main clinical features are hypocalcemia, hyperphosphatemia, and resulting tetany, convulsions, or epileptoid seizures. Patients with PHP 1b often present…
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Clinical manifestations of scrub typhus in atypical endemic areas and application of metagenomic and targeted next-generation sequencing： an analysis of seven cases
Objective This study aims to summarize the clinical characteristics of patients with scrub typhus in atypical epidemic areas, and explore the application value of metagenomic next-generation sequencing (mNGS) and targeted next-generation sequencing (tNGS) in etiological diagnosis. Methods A…
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Caffeine-mediated alleviation of imbalance of calcium homeostasis and apoptosis in cardiomyocytes caused by RyR2 knockdown
Objective This study aims to investigate the effects of low-concentration caffeine on calcium homeostasis and apoptosis in rat cardiomyocytes with ryanodine receptor 2 (RyR2) knockdown. Methods Neonatal Sprague-Dawley (SD) rats of specific pathogen-free (SPF) grade were used, and neonatal rat…
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Current status and research advances in laboratory diagnosis of non-tuberculous mycobacteria
Non-tuberculous mycobacteria (NTM) are a group of opportunistic pathogens widely present in the environment. The global incidence of NTM infections and associated drug resistance rates are increasing. Although unified global surveillance data are lacking, studies based on national surveillance or…
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Epidemiological status and drug resistance survey of protothecosis in China from 2015 to 2025
Objective Prototheca is a unicellular microalga belonging to the family Chlorellaceae that has lost its chlorophyll and the ability to perform photosynthesis, exhibiting biological characteristics intermediate between algae and fungi. Protothecosis is predominantly an exogenous infection, with…
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Current status and future prospects of drug treatment strategies for functional cure of chronic hepatitis B
Chronic hepatitis B (CHB) remains a major global health challenge. Functional cure represents the ideal therapeutic endpoint for CHB. The pathogenesis of CHB is complex, including hepatitis B virus (HBV) DNA integration, persistent covalently closed circular DNA, and impaired specific immune…
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Advances in novel tumor markers for cancer diagnosis and treatment in an era of integration of multi-omics technologies and artificial intelligence
The integration of multi-omics technologies and artificial intelligence is jointly promoting the application of more precise and dynamic novel tumor markers in cancer diagnosis and treatment. In terms of genomics, high-throughput sequencing technologies have promoted in-depth research into tumor…
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Correlation between serum soluble CD206 and disease activity in patients with anti-neutrophil cytoplasmic antibody-associated glomerulonephritis
Objective This study aims to investigate the expression characteristics of serum soluble CD206 (sCD206) in patients with anti-neutrophil cytoplasmic antibodies (ANCA)-associated glomerulonephritis (AGN) and its value in assessing disease activity. Methods A total of 54 AGN patients hospitalized in…
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Prospective study on value of 31P magnetic resonance spectroscopic imaging in evaluating efficacy of hepatic arterial infusion chemotherapy for advanced-stage hepatocellular carcinoma
Objective This study aims to investigate the value of 31P magnetic resonance spectroscopy imaging (31P MRSI) in evaluating the therapeutic efficacy of the first cycle of hepatic arterial infusion chemotherapy (HAIC) for patients with hepatocellular carcinoma (HCC). Methods A total of 13 male…
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Features and advances in diagnosis and treatment of atypical Parkinson syndromes
Parkinson syndrome (PDS) is a group of neurological syndromes characterized by bradykinesia, rigidity, resting tremor, and postural instability as core manifestations, mainly including Parkinson's disease (PD), atypical Parkinson syndromes (APSs), and secondary Parkinson syndromes. APSs are a group…
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Progress in blood-based biomarkers for diagnosis of Alzheimer's disease
Alzheimer's disease (AD), as the primary cause of dementia among the elderly globally, has become a serious public health challenge. However, traditional cerebrospinal fluid (CSF) testing and positron emission tomography (PET) are difficult to implement for large-scale population screening and…
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Bidirectional relationship between sleep disorders and Parkinson's disease
Parkinson's disease (PD), the second most common neurodegenerative disorder, shares some core pathological features with Alzheimer's disease (AD), namely the accumulation of misfolded neurotoxic proteins leading to neuronal dysfunction and death, and both are multifactorial diseases resulting from…