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Chinese Journal of Contemporary Neurology and Neurosurgery
Scopus
ISSN 1672-6731 · Tianjin Huanhu Hospital · 2,978 articles in the index
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Journal Article
Mechanisms and clinical advances in transcranial alternating current stimulation for the treatment of depression
Transcranial alternating current stimulation (tACS) is a non-invasive neuromodulation technique that applies low-intensity sinusoidal currents at specific frequencies to interact with endogenous neural oscillations. By modulating neuronal firing synchrony, tACS can improve neural functions. In…
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Journal Article
Current clinical application of vagus nerve stimulation
Vagus nerve stimulation (VNS) as an established neuromodulation technique, has seen a continuous expansion in its range of approved indications since its initial approval for the adjunctive treatment of drug-resistant epilepsy. As of 2025, the Food and Drug Administration (FDA) has approved VNS for…
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Journal Article
Progress on the application of deep brain stimulation in refractory mental disease
Deep brain stimulation (DBS), a reversible and adjustable neuromodulation technique, has expanded from its initial application in movement disorders to the treatment of mental disease. This review systematically summarizes the current applications and research progress of DBS in treatment-resistant…
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Journal Article
Progress on the application of deep brain stimulation in motor dysfunction after stroke
Stroke is one of the main causes of adult disability. Patients after stroke often suffer from motor dysfunction, which affects their quality of life and requires effective treatment methods. Deep brain stimulation (DBS), as a mature neuromodulation technique, has shown significant potential in…
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Journal Article
Progress on non-invasive electrical and magnetic neuromodulation therapy for cognitive impairment in posttraumatic stress disorder
Posttraumatic stress disorder (PTSD) is a severe mental disorder triggered by traumatic events. Its core clinical symptoms include intrusive memories, avoidance behaviors, negative alterations in mood and cognitive disorder, and hyperarousal. These symptoms are closely associated with aberrant…
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Journal Article
Prolonged consciousness disorder and brain-computer interface: a new paradigm of medicine-engineering convergence in neuromodulation
Accurate assessment and intervention for prolonged consciousness disorder remain critical challenges in neuroscience. Brain-computer interface (BCI) offers a novel pathway for diagnosis and treatment of consciousness disorder by decoding neural signals, reconstructing conscious communication, and…
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Journal Article
The modification and application precautions of the WHO classification of tumors of the central nervous system (fifth edition)
The fifth edition of the WHO classification of tumors of the central nervous system (CNS5, 2021) is based on the concept of precision medicine. CNS5 incorporates a large number of new molecular diagnostic indicators as well as more detailed clinical and molecular epidemiological follow-up data…
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Journal Article
Advances in clinical practice of spinal cord stimulation
Spinal cord stimulation (SCS) is a non-pharmacological neuromodulation technique used to treat various neurological disorders. It functions by delivering electrical impulses to specific areas of the dorsal columns of the spinal cord, thereby modulating abnormal neural signal transduction to…
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Journal Article
Deep brain stimulation in drug-resistant epilepsy: current status and future perspectives
Drug-resistant epilepsy remains a major challenge in management of epilepsy, with approximately half of patients being unsuitable candidates for resective surgery. In recent years, deep brain stimulation (DBS), as a neuromodulation therapy, has demonstrated promising potential. This review…
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Journal Article
Advances in neuromodulation for drug-resistant epilepsy: transitioning from open-loop stimulation to closed-loop stimulation
Over the recent years, electrical stimulation therapy has rapidly evolved as a commonly used neuromodulation therapy for epilepsy. Although open-loop stimulation [such as vagus nerve stimulation (VNS) and anterior nucleus of the thalamus deep brain stimulation (ANT-DBS)] has achieved certain…
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Journal Article
Clinical progress of neuromodulation therapy for spinocerebellar ataxia type 3
Spinocerebellar ataxia type 3 (SCA3) is an autosomal dominant neurodegenerative disease, with core clinical symptoms including motor disorders and cognitive impairment. Since there is currently no effective radical treatment, the development of targeted diagnostic strategies and intervention…
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Journal Article
Clinical application and future prespectives of brain-computer interface
Brain-computer interface (BCI) technology, by establishing direct communication pathways between the brain and external devices, has brought groundbreaking advancements to the diagnosis, treatment and rehabilitation of neurological disorders. A typical BCI system comprises the core steps of "signal…
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Journal Article
Innovative research on medicine-engineering convergence in neuromodulation
Nervous system diseases have emerged as a leading cause of health loss and disability worldwide, and are increasingly recognized as a global public health challenge. In response to this challenge, the development and application of neuroscience technologies for treating nervous system diseases are…
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Journal Article
Multimodal cognitive rehabilitation interventions for cognitive dysfunction disorders
Cognitive dysfunction disorders are characterized by acquired and persistent cognitive dysfunction as the disease core manifestation, which has become the major public health issue and threatening the health of middle-aged and elderly population. Given the limited efficacy of conventional…
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Journal Article
Advance in Lecanemab therapy for Alzheimer's disease
Deposition of amyloid β-protein (Aβ) in the brain is a key pathogenesis and early change in Alzheimer's disease (AD). Clearing Aβ through anti-Aβ monoclonal antibody drugs is an important strategy for disease-modifying thrapy (DMT). Lecanemab is the first approved anti-Aβ monoclonal antibody durg…
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Journal Article
Advance in the clinical diagnosis and treatment of Alzheimer's disease
The paradigm for diagnosing and treating Alzheimer's disease (AD) is undergoing a profound transformation, moving towards a biomarker-driven and early-intervention-oriented stage. In diagnosis, the emergence of high-performance biomarkers such as plasma p-tau217 has significantly advanced the…
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Journal Article
Progress on frontotemporal dementia
Frontotemporal dementia (FTD) is the second most common type of early-onset dementia after Alzheimer's disease (AD), severely impairing patients' quality of life and increasing the burden of family care. Currently, there is a lack of reliable biomarkers for its diagnosis, and reliance on clinical…
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Journal Article
Progress on the pathogenesis of Alzheimer's disease
The pathogenesis of Alzheimer's disease (AD) has not been fully elucidated to date, posing tremendous challenges for clinical treatment. An in-depth exploration of its pathogenesis is of great significance for early screening, prevention, diagnosis and treatment of AD. This paper comprehensively…
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Journal Article
Comparison between the MIND-China study and similar international large-scale cohort studies
Alzheimer's disease (AD) continuum is characterized by an insidious onset and a continuous disease spectrum, making early identification particularly challenging. Its initiation and progression result from complex interactions among amyloid β-protein (Aβ) and microtuble-associated protein tau…
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Journal Article
Interpretation of "Specification for interdisciplinary team service of the elderly with cognitive impairment"
The "Specification for interdisciplinary team service of the elderly with cognitive impairment" (T/CAWAORG 053-2025, the Specification) is an implementation guideline developed by the Chinese Aging Well Association for elderly patients with cognitive impairment. It aims to provide standardized…
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