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The Iraqi Journal of Medical Sciences
ISSN 1681-6579 · Al-Nahrain University/College of medicine · 2.835 artikel di indeks
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Artikel Jurnal
Immunomodulatory Effects of Vitamin D: Bridging Cellular Defense and Inflammatory Control
Vitamin D, an evolutionarily conserved molecule essential for diverse life forms ranging from phytoplankton to mammals, plays a critical role in health beyond its classical functions. It promotes osteoclast differentiation indirectly via receptor activator of nuclear factor κB (RANKL) upregulation…
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Assessment of Neudesin Serum Levels in Pre-Diabetes and Newly Diagnosed Type 2 Diabetes Mellitus
Background:Type 2 Diabetes Mellitus (T2DM) is a metabolic disorder characterized by chronic hyperglycemia due to insulin resistance and impaired insulin secretion. Prediabetes, an intermediary condition where blood glucose levels are elevated but not yet diagnostic for diabetes, poses a significant…
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Artikel Jurnal
Evaluation of the Level of Immune Checkpoint Programmed Death Protein 1 (PD-1) in Toxoplasmosis
Background: Toxoplasma gondii (T. gondii) is known to manipulate host immune responses to establish a persistent infection. This manipulation involves modulation of immune regulatory pathways, including those mediated by checkpoint molecules like programmed cell death protein 1 (PD-1). The parasite…
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Sarcopenia Frequency Among a Sample of Iraqi COVID-19 Survivors/ A Single Center Study
Background: Coronavirus disease 2019 (COVID-19) induced by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has had a massive negative impact of the healthcare systems worldwide, most obvious in its acute stage, but subtler chronic sequelae are being recognized. Sarcopenia, a…
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Artikel Jurnal
Awareness about Risk and Preventive Factors for Knee Osteoarthritis among College Teachers in Baghdad City, Iraq in 2023
Background: It is important for college teachers to have awareness about knee osteoarthritis (OA) so that they can provide appropriate support and accommodation for themselves and their students with this condition. Objective: To assess the awareness level, the risk factors for OA and find the…
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Artikel Jurnal
Circulating MicroRNA-126: A Candidate Biomarker for Early Detection of Type 2 Diabetes Mellitus
Background: Type 2 diabetes mellitus (T2DM) is characterized by difficulties of insulin utilization or synthesis. MicroRNAs (miRs), family has a basic role in control of glucose level in blood. Objective: To estimate the serum expression of miR-126 as a candidate biomarker for early detection of…
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Artikel Jurnal
Evaluation of the Effect of Smoking on IL-6 and IL-10 in Relation to Oral Health Status: An Observational Cross-Sectional Comparative study
Background: Tobacco smoke contains thousands of chemical compounds, many of which are toxic and capable of inducing oxidative stress and inflammation. Interleukin (IL)-6 and IL-10 are cytokines crucial for immune regulation, inflammation, and hematopoiesis, produced by several cells. Objective: To…
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Artikel Jurnal
Vitamin D Status in Preterm Neonates in The NICU of Al-Imamein Al-Kadhimein Medical City
Background: Vitamin D is a fat-soluble vitamin that played an important role in bone metabolism (mineralization). It was considered a prohormone and had important role in the optimal function of many organ systems and may be a risk modifying factor for many chronic diseases. Objective: To assess…
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Artikel Jurnal
Role of Cressa cretica on Serum Lipid Profile and Histopathological Changes of Ovaries in Induced Polycystic Ovary Syndrome in Female Rats
Background: Polycystic ovary syndrome (PCOS), also called Stein-Leventhal syndrome, is a heterogeneous endocrine disorder that affects approximately 4-8% of women of reproductive age. Objective: To study the effect of Cressa cretica (C. cretica) leaves extract on induced PCOS in rat model, to…
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Artikel Jurnal
The Role of 8-Isoprostane as A Biomarker in Chronic Kidney Disease Progression
Background: The progression of chronic kidney disease (CKD) and the development of complications are facilitated by oxidative stress, which is a progressive condition. 8-Isoprostane, a byproduct of lipid peroxidation, has the potential to serve as a biomarker that reflects kidney function and…
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Artikel Jurnal
Biosynthesis of Selenium Nanoparticles by Ralstonia mannitolilytica and Evaluation of Their Antibacterial Activity
Background: Using microorganisms such as Ralstonia mannitolilytica (R. mannitolilytica), to create selenium nanoparticles (SeNPs) offers a promising path for Grammy advancement. Antibiotic resistance poses a formidable challenge, particularly against multidrug-resistant (MDR) bacteria. The…
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Artikel Jurnal
The Potential Role of Herpes Simplex Virus and Socio-Clinical Factors in Autism Risk in Iraqi Children
Background: Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by social communication challenges, repetitive behaviors, and restricted interests. The etiology is elusive, but it is believed to involve genetic, environmental, and viral factors. The Herpes simplex virus…
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Artikel Jurnal
Minimally Invasive Treatment of Pilonidal Sinus Abscess Using Diode Laser: A clinical Approach
Background: Pilonidal sinus (PNS) is an inflammatory condition in the natal cleft above the coccyx. Its treatment is highly variable and can include observation and hair removal, incision and drainage, or excision with sometimes complex surgical reconstruction, however, the usual treatment for PNS…
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Artikel Jurnal
Hepatitis B Vaccination in Responsive and Non-Responsive Patients with End-Stage Kidney Disease undergoing Hemodialysis
Background: Hepatitis B virus (HBV) vaccination is known as the best way to prevent the spread of the Hepatitis B virus in hemodialysis centers. Objective: To study the effectiveness of the Euvax B vaccine in end-stage kidney disease (ESKD) Iraqi patients on hemodialysis already not responded to a…
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Artikel Jurnal
Metabolic Effect of Spexin on Obesity and Diabetes: A Mini Review
Spexin is an adipokine and neuropeptide that is extensively expressed in a number of tissues and organs, like the pancreas, fat, small intestine, liver, stomach, and other endocrine tissues to perform a variety of functions such as glucose and lipid metabolism. Spexin might be a biomarker for…
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Artikel Jurnal
Evaluation The Level of Osteocalcin in Type 2 Diabetes Mellitus in A Sample of Iraqi Patients with and without Osteoporosis
Background Osteoporosis (OP) is a common bone illness that affects people worldwide and is characterized by reduced bone mineral density (BMD) and deteriorated bone tissues, making the bones fragile. Type 2 diabetes mellitus (T2DM) characterized by hyperglycemia, accounts for about 90% of all…
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Artikel Jurnal
Association between Dietary Habits and Clinical Outcomes in Pregnant Women with Gestational Diabetes in Baghdad City Background Osteoporosis (OP) is a common bone illness that affects people worldwide and is characterized by reduced bone mineral density (
Background Osteoporosis (OP) is a common bone illness that affects people worldwide and is characterized by reduced bone mineral density (BMD) and deteriorated bone tissues, making the bones fragile. Type 2 diabetes mellitus (T2DM) characterized by hyperglycemia, accounts for about 90% of all…
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Artikel Jurnal
Diagnostic Accuracy of Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 in Serum of Patients with Pleural Effusion
Background Pleural effusion (PE) is an abnormal buildup of fluid in the pleural space that typically results from excessive fluid production and/or reduced lymphatic absorption. It is still difficult to distinguish between benign and malignant exudative PE in clinical settings. Matrix…
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Artikel Jurnal
Association of Serum Levels of Fibroblast Growth Factor Receptor-3 and Cytokeratin-19 with Invasive and Non-invasive Bladder Cancer in a Sample of the Iraqi Population
Background Bladder cancer (BC) is the tenth most prevalent cancer worldwide. The fibroblast growth factor receptor 3 (FGFR3) controls essential signaling pathways that govern several cellular processes, including proliferation and migration. Cytokeratin-19 (CYFRA21-1) is a protein belonging to the…
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Artikel Jurnal
The Predictive Utility of the [Tissue Inhibitor of Metalloproteinases-2 * Insulin-like Growth Factor Binding Protein 7] Index for the Detection of Subclinical Kidney Injury in Patients with Inflammatory Bowel Disease
Background Early detection of renal stress in patients with inflammatory bowel disease (IBD) is crucial to prevent progression to overt kidney injury. The tissue inhibitor of metalloproteinases-2 (TIMP-2) * insulin-like growth factor binding protein 7 (IGFBP7) index has been proposed as a…
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