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Journal of Microbiology, Immunology and Infection
Scopus
ISSN 1684-1182 · Elsevier · 1.277 artikel di indeks
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Artikel Jurnal
Longitudinal molecular epidemiology of ceftriaxone-resistant enterobacterales in intra-abdominal and urinary tract infections: A decade-long SMART surveillance study in Taiwan (2009–2019)
Background: Third-generation cephalosporin-resistant Enterobacterales is a recognized global concern. This study investigated the molecular epidemiology of β-lactamase genes and antimicrobial susceptibility patterns among ceftriaxone-resistant Enterobacterales causing intra-abdominal and urinary…
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Artikel Jurnal
A comparative analysis of HbA1c, glycated albumin, and fasting plasma glucose for glycemic assessment in people living with HIV
Background: People living with HIV (PLWH) are at increased risk for metabolic disorders, including diabetes and prediabetes. While hemoglobin A1c (HbA1c) is widely used for glycemic assessment, its reliability in PLWH is questioned due to altered red blood cell turnover. Glycated albumin (GA) has…
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Artikel Jurnal
Mitigating unfavourable treatment outcomes and acquired rifampicin resistance in isoniazid-resistant tuberculosis: the role of fluoroquinolone
Background: Rifampicin (RMP), ethambutol, and pyrazinamide (PZA) for 6–9 months were recommended for the management of isoniazid-resistant, rifampicin-susceptible tuberculosis (Hr-TB), but recommendations on fluoroquinolones (FQs) were inconsistent. We investigated treatment outcomes and acquired…
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Artikel Jurnal
An interpretable machine learning approach to evaluate 30-day mortality risk in patients with community-onset bacteremia
Background: Machine learning (ML) techniques are increasingly being used in health outcome research to develop predictive models. However, ML models are often referred to as “black box models” because they lack interpretability. Our goal was to develop an ML model to predict mortality risk in…
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Artikel Jurnal
Cellular and humoral immunity following two AZD1222 and two booster vaccinations in hemodialysis patients
Background: Dialysis patients are vulnerable to SARS-CoV-2 infection and subsequent complications. However, the vaccine-induced immunity, especially against new variants, following two AZD1222 and two booster doses in hemodialysis patients remain largely unknown. Methods: In this observational…
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Artikel Jurnal
Multiple organ dysfunction score for assessing patients with severe fever with thrombocytopenia syndrome
Background/purpose: Severe Fever with Thrombocytopenia Syndrome (SFTS) is a tick-borne viral disease with high mortality rates. The Multiple Organ Dysfunction Score (MODS) is used for assessing organ dysfunction and predicting outcomes in critically ill patients. We aimed to evaluate the…
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Artikel Jurnal
Genomic analysis of Mycobacterium abscessus isolates from non-cystic fibrosis patients in Thailand: phylogeny, subspecies distribution, and antimicrobial resistance profiles
Background: Mycobacterium abscessus (MABS) is a clinically significant nontuberculous mycobacterium, and its drug resistance poses substantial therapeutic challenges. Comprehensive genomic and phenotypic analyses are essential for elucidating the mechanisms underlying this resistance and enhancing…
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Artikel Jurnal
Dexamethasone treatment is associated with a higher HBsAg sero-clearance rate in HBeAg-positive patients with hepatitis B flares
Purpose: Short-term dexamethasone has been used in patients with chronic hepatitis B flares to reduce inflammation in the liver. We aim to identify the potential population that may benefit from dexamethasone treatment. Methods: A retrospective cohort study was conducted involving 856 hospitalized…
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Artikel Jurnal
A retrospective cohort study of Mycobacterium kansasii complex pulmonary infections at a tertiary teaching hospital
Background: Mycobacterium kansasii complex (MKC) is the second common slowly growing mycobacterium associated with pulmonary diseases, typically presenting as chronic, progressive respiratory symptoms with structural lung damage. This study aimed to identify the prognostic factors, genotypes…
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Artikel Jurnal
Exploring the role of the CCAAT-binding complex in cell wall maintenance and biofilm formation in Candida albicans
Background: The conserved CCAAT-binding complex (CBC) specifically recognizes and binds to the CCAAT motif present in eukaryotic promoters, thereby controlling gene transcription. In Candida albicans, the CBC cooperates with another transcription factor, Hap43, to regulate iron homeostasis…
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Artikel Jurnal
High-dose daptomycin versus linezolid for the treatment of vancomycin-resistant Enterococcus faecium bloodstream infections: Role of pharmacodynamic target attainment
Background: Although high-dose daptomycin (≥8 mg/kg) and linezolid are recommended treatments for vancomycin-resistant Enterococci (VRE) bloodstream infection (BSI), direct comparisons and the impact of achieving prespecified pharmacokinetic/pharmacodynamic (PK/PD) target on outcomes remain…
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Artikel Jurnal
Interleukin 27 (IL-27) productions in the liver microenvironment confer an immunosuppressive role and enhance hepatitis B viral persistence
Background: Persistent chronic hepatitis B virus (HBV) infection leads to chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. The immunosuppressive tissue microenvironment in the liver restricts the immune response, potentially facilitating persistent HBV infection. This study…
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Artikel Jurnal
Components of cardiometabolic risk factors predict liver-related events in patients cured of hepatitis C Virus
Background: The new nomenclature of steatotic liver disease (SLD) was proposed in June 2023. The effects of cardiometabolic risk factors (CMRFs) on liver-related events (LREs) in patients achieving chronic hepatitis C (CHC) eradication are unknown. Methods: This study recruited 1185 patients cured…
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Artikel Jurnal
Effectiveness of the monovalent XBB.1.5 COVID-19 vaccines: A systematic review and meta-analysis
Background: Coronavirus disease 2019 (COVID-19) remains a public health concern even after its pandemic status officially ended on May 5, 2023, when XBB became the globally predominant SARS-CoV-2 variant. Amid population immunity, the benefit of the monovalent XBB.1.5 vaccines remains uncertain…
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Artikel Jurnal
Molecular mechanisms and targets underlying immune evasion by human cytomegalovirus
Human cytomegalovirus (HCMV) establishes lifelong latency in humans largely through the evolution of sophisticated immune evasion strategies that allow it to escape recognition and clearance by the host immune system. While significant progress has been made in elucidating the mechanisms underlying…
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Artikel Jurnal
Chronicity and quality of life in Chikungunya virus infection: a cross-sectional study in Barranquilla, Colombia
Chikungunya virus (CHIKV) infection is the second most widespread arboviral disease after dengue, and a significant number of patients suffer from a spectrum of chronic symptoms. Our objective was to estimate the prevalence of chronic CHIKV infection and its impact on the quality of life of…
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Artikel Jurnal
Recommendations and guidance for pneumococcal vaccination for adults in Taiwan
Streptococcus pneumoniae remains a global health concern, causing diseases from sinusitis, otitis media, to invasive pneumococcal diseases (IPD), such as bacteremia, bacteremic pneumonia, empyema, and meningitis. Key IPD risk factors include age under five or over 50 years, chronic medical…
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Artikel Jurnal
Aspergillus-specific immunoglobulin G seropositivity and lung function decline in patients with chronic lung diseases: A prospective cohort study
Background: Aspergillus-specific immunoglobulin G (IgG) positivity typically indicates exposure to Aspergillus species, but its clinical significance among chronic lung diseases remains uncertain. Methods: This prospective study enrolled patients with bronchiectasis, chronic obstructive pulmonary…
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