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Journal of Research in Medical Sciences
Scopus
ISSN 1735-1995 · Wolters Kluwer Medknow Publications · 3,056 articles in the index
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Journal Article
Automatic assessment of lung involvement in systemic sclerosis using deep learning
Background: Systemic sclerosis (SSc) is a relatively uncommon connective tissue disorder, commonly manifesting as interstitial lung disease (ILD) and affecting both the lung parenchyma and the modification of the space between endothelium and epithelium. Imaging modalities like computed tomography…
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Journal Article
Incidence of urethral stricture and urinary incontinence after transurethral resection of the prostate
Background: Transurethral resection of the prostate (TURP) is the standard treatment for benign prostatic hyperplasia (BPH). The incidence of postoperative urethral stricture (US) and urinary incontinence remains clinically important, and their predictors are not fully established. This study aimed…
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Journal Article
Peripheral perfusion-guided versus routine fluid therapy in sepsis: A randomized controlled pilot trial
Background: Sepsis remains a leading cause of morbidity and mortality among critically ill patients. Fluid resuscitation is essential, but conventional protocols often lack individualized assessment of tissue perfusion, risking underresuscitation or fluid overload. The peripheral perfusion index…
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Journal Article
Linear psoriasis and Koebner phenomenon: A review
Linear psoriasis (LP) is an unusual form of psoriasis with an unidentified prevalence and is characterized by psoriatic papules and plaques in a Blaschko linear distribution. Based on clinical features, this disorder is divided into two types: isolated LP and superimposed LP. Previous studies have…
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Journal Article
The location of physical activity determines its efficacy on Vitamin D status: Evidence from a meta-analysis
Background: Numerous epidemiological studies have identified a positive correlation between increased physical activity and raised levels of serum 25-hydroxyvitamin D (25(OH)D). However, it remains uncertain whether this correlation implies a cause-and-effect relationship. The aim of this…
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Journal Article
Rising in level of liver biomarkers after different types of bariatric surgery; is there any concern?
Background: Previous studies indicated that metabolic and bariatric surgery (MBS) is a well-known procedure for considerable and sustainable weight loss. While the studies showed that MBS may unfavorably influence and stimulate hepatic dysfunction by raising the aspartate aminotransferase (AST) and…
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Journal Article
Current perspectives on lipid management in diabetic kidney disease: Can fibrates offer advantages over statins for renal outcomes?
Diabetic kidney disease (DKD) affects 30%–40% of patients with diabetes mellitus (DM). Dyslipidemia is a key modifiable risk factor for the development and progression of DKD. Statins remain the mainstay of lipid management in DM, but concerns exist about their renal effects and limited impact on…
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Journal Article
The effect of riboflavin on the mean attack frequency, severity, and duration of migraine headaches: A systematic review and dose–response meta-analysis of clinical trials
Background: Due to the anti-inflammatory and antioxidant effects of riboflavin, this vitamin can be effective in improving migraine. However, due to conflicting results in previous studies, the present study aimed to determine the effectiveness of riboflavin in improving migraine in a systematic…
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Journal Article
The Triglyceride-Glucose Index is associated with hospital and Intensive Care Unit Mortality in critically ill patients with Acute Coronary Syndrome
Background: Acute coronary syndrome (ACS) is one of the leading causes of death, but there is no attention paid to the risk stratification of patients with ACS. Aims: We evaluated the utility of the triglyceride-glucose (TyG) index in predicting the hospital and intensive care unit (ICU) mortality…
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Journal Article
Pentosidine as a biomarker for bone fragility: Molecular mechanisms, clinical relevance, and detection strategies
Fractures pose a significant public health challenge due to their association with poor health outcomes and increased healthcare costs. While bone mineral density (BMD) remains a fundamental element of fracture risk assessment, it fails to fully capture bone quality, including strength and…
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Journal Article
Depressive symptoms and incident osteoporosis in older adults: A cohort study with competing-risk and mediation analyses in English Longitudinal Study of Aging
Background: Evidence on depressive symptoms and skeletal health is largely cross-sectional and rarely addresses competing risk, dose-response, or potential behavioral pathways. We examined the association between baseline depressive symptoms and incident osteoporosis in older adults, accounting for…
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Journal Article
Chromodomain helicase DNA-binding proteins and orofacial cleft
Orofacial clefts (OFCs) are among the most common congenital anomalies, arising from a complex interplay of genetic and environmental factors that disrupt the precisely coordinated processes of craniofacial development. This review collects current evidence on the role of the chromodomain helicase…
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Journal Article
Single-cell transcriptomic profiling of human kidneys uncovers profound principal cell responses to diabetic conditions, enabling targeted drug discovery
Background: Ranked as the fifth leading global health burden in 2022, diabetes mellitus is the driver of diabetic kidney disease (DKD), a condition responsible for nearly half of end-stage kidney disease cases. Despite its significant impact, therapeutic progress in DKD is hindered by an incomplete…
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Journal Article
The best type of probiotic for the prevention and treatment of neonatal physiological jaundice: A systematic review and meta-analysis
Background: Gut microbiota play an important role in bilirubin metabolism and may influence the course of neonatal physiological jaundice. This systematic review and meta-analysis aimed to evaluate the strain-specific efficacy of probiotics in the prevention and adjunctive treatment of neonatal…
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Journal Article
Exploring the mechanisms connecting the sympathetic nervous system and type 2 diabetes: Focus on renal denervation
The interplay between sympathetic nervous system activation and metabolic disorders, particularly type 2 diabetes mellitus (T2DM) and hypertension, has been increasingly recognized as a critical factor in cardiovascular morbidity and mortality. This review explores the potential mechanisms linking…
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Journal Article
Platelet-rich plasma versus granulocyte colony-stimulating factor in addressing recurrent implantation failure: A randomized, double-blind clinical trial
Background: The aim of the study is to evaluate the effect of platelet-rich plasma (PRP) versus granulocyte colony-stimulating factor in addressing recurrent implantation failure. Materials and Methods: Fifty patients were randomly assigned to two treatment groups: PRP and granulocyte…
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Journal Article
Latent autoimmune diabetes mellitus and its characteristics amongst adults diagnosed with type 2 diabetes at a single diabetes center in Medina, Saudi Arabia
Background: To estimate the frequency and characteristics of Latent Autoimmune Diabetes in Adults (LADA) in patients diagnosed with type 2 diabetes mellitus (T2DM) at a single diabetes center in Medina, Saudi Arabia. Materials and Methods: This was a cross-sectional study involving patients with…
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Journal Article
Nursing interventions including psychological support and quality of life determinants in patients with dysphagia following stroke
Background: Poststroke dysphagia (PSD) affects nearly half of stroke survivors and impairs health-related quality of life. Nursing interventions increasingly integrate psychological support, yet their effectiveness remains unclear. This systematic review and meta-analysis evaluated the impact of…
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Journal Article
Higher anxiety score in patients with non-obstructive coronary artery disease
Background: There is insufficient evidence on the relationship between psychological distress and patients with non-obstructive coronary artery disease (NOCAD) who experience angina symptoms despite having non-significant narrowing or normal coronary arteries. Therefore, our aim is to evaluate the…
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