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The Korean Journal of Helicobacter and Upper Gastrointestinal Research
Scopus
ISSN 1738-3331 · Korean College of Helicobacter and Upper Gastrointestinal Research · 541 artikel di indeks
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Artikel Jurnal Teks lengkap
Efficacy of Eradication for Gastric Cancer Prevention in Older Adults
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Artikel Jurnal Teks lengkap
Management in Older Adults: Current Perspectives From Japan
Helicobacter pylori infection—although its overall prevalence has declined over time—remains a major cause of peptic ulcer disease and gastric cancer, particularly among older adults in aging societies such as Japan. While eradication therapy is known to reduce the gastric cancer risk, its use in…
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Clinical Outcomes of Tegoprazan Versus Proton Pump Inhibitors in Patients Receiving Antiplatelet Therapy After Percutaneous Coronary Intervention: A Retrospective, Observational Study
Objectives Tegoprazan is an alternative to proton pump inhibitors (PPIs). This study evaluated the occurrence of upper gastrointestinal (GI) and cardiovascular (CV) complications in patients with ischemic heart disease undergoing antiplatelet therapy after percutaneous coronary intervention (PCI)…
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Management of Non-Variceal Upper Gastrointestinal Bleeding
Acute non-variceal upper gastrointestinal bleeding (NVUGIB) is a significant medical emergency associated with high morbidity and 5%–10% mortality. NVUGIB originates from sources proximal to the ligament of Treitz and primarily encompasses peptic ulcer bleeding, Mallory–Weiss tears, and malignant…
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Endoscopic Management of Post-Sleeve Gastrectomy Leaks Using Long, Fully Covered Stents
Gastric leaks after laparoscopic sleeve gastrectomy are serious complications with mortality rates of up to 10%. Conventional self-expanding metal stents exhibit high migration rates (up to 58%), limiting their efficacy. Large, fully covered megastents that reduce migration rates are poorly…
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Natural History of Gastric Subepithelial Lesions Measuring 1 to 2 cm
Objectives Management strategies for subepithelial lesions (SELs) measuring 1–2 cm remain undefined in most guidelines due to limited data. We aimed to establish a practical clinical approach by analyzing the long-term outcomes of SELs in this size range. Methods We retrospectively reviewed cases…
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Antimicrobial Peptides: Potential Therapeutic Substitute for Antibiotics in Infection
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Positivity by 16S rRNA Gene PCR in Fecal Samples From Patients With Gastroduodenal Symptoms: A Retrospective Observational Study
Objectives Helicobacter pylori is recognized as one of the most virulent microorganisms within the genus Helicobacter owing to its genomic characteristics. It has been associated with diseases, such as peptic ulcers and gastric cancer. This study aimed to evaluate Helicobacter pylori positivity in…
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Endoscopic Submucosal Dissection for Early Gastric Cancer: Current Standard Indication and Management
Endoscopic submucosal dissection (ESD) has been established as the standard treatment for early gastric cancer, enabling en bloc resection regardless of lesion size and offering high curability with organ preservation. The indications for ESD have expanded with the accumulation of long-term data…
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Underwater Endoscopic Resection for the Rare Periampullary Tumor
Composite gangliocytoma/neuroma and neuroendocrine tumors (CoGNETs) are extremely rare periampullary neoplasms composed of neuroendocrine epithelial, Schwannian spindle, and ganglion cells. Although endoscopic papillectomy or surgery have been used to treat ampullary CoGNETs, underwater endoscopic…
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Treatment of Infection in Korea: An Evidence-Based Analysis of the Upcoming 2025 Guideline
The efficacy of clarithromycin-containing triple therapy (TT) against Helicobacter pylori has declined in Korea, with recent first-line eradication rates falling below 70%. Clarithromycin resistance exceeded 30%, undermining the standard regimen for H. pylori. These trends necessitate a change in…
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Identification of Antimicrobial Peptide Variants From Against -Mediated Gastric Cancer: An In-Silico Approach
Objectives Increased antimicrobial resistance has necessitated innovative therapeutic strategies to combat Helicobacter pylori, a key contributor to gastric cancer (GC). Antimicrobial peptides (AMPs) derived from probiotic Lactobacillus spp. offer a promising alternative to antibiotics, with…
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Gastric Plexiform Fibromyxoma Presenting With Gastrointestinal Hemorrhage
Plexiform fibromyxoma (PF) is a very rare mesenchymal tumor that presents as a subepithelial lesion (SEL). Endoscopically, it is almost indistinguishable from other SELs, and it has been reported to cause hemorrhage. Herein, the case of a patient diagnosed with PF after surgical resection for…
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Gastritis: Pathophysiology, Diagnosis, and Clinical Implications
Gastritis encompasses a heterogeneous spectrum of inflammatory and structural alterations of the gastric mucosa arising from diverse etiologies, including Helicobacter pylori infection, autoimmune processes, and drug-induced mucosal injury. Recent advances in endoscopy technique, histological…
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Interaction Between Metabolic Diseases, GLP-1 Receptor Agonists, and Infection: An Updated Evidence Summary
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A Subepithelial Tumor With Surface Changes Removed by Endoscopic Submucosal Dissection
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Nationwide Survey on Endoscopic Submucosal Dissection for Early Gastric Cancer in Korea: Results From the Korean College of and Upper Gastrointestinal Research (KCHUGR) 2023 Survey
Objectives Endoscopic submucosal dissection (ESD) has become a standard minimally invasive treatment for selected patients with early gastric cancer (EGC). This study presents the first nationwide survey of patients with EGC treated with ESD in 2023, conducted by the Korean College of Helicobacter…
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Autoimmune Gastritis Associated With a Gastric Hyperplastic Polyp: Two Case Reports and Review of its Neoplastic Potential
Autoimmune gastritis (AIG) results in the loss of oxyntic glands, achlorhydria, and hypergastrinemia and frequently leads to the development of gastric hyperplastic polyps (GHPs). AIG is increasingly being recognized as a major contributor to corpus-dominant atrophy in East Asia. Despite its…
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A 65-Year-Old Man With Abdominal Pain, Duodenal Ulceration, and Skin Lesions