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Journal of the International AIDS Society
Scopus
ISSN 1758-2652 · Wiley · 895 articles in the index
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Journal Article
A cluster randomized trial of Visitect CD4 Advanced Disease platform among outpatients with advanced HIV disease in Uganda
Abstract Introduction Despite significant progress in HIV care globally, a persistent 30–40% of people present with advanced HIV disease with ≤200 CD4 cells/µl. The Visitect CD4 Advanced Disease platform is a point‐of‐care CD4 test being implemented in resource‐limited settings. We sought to assess…
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Journal Article
Cost‐effectiveness of leveraging long‐acting injectable cabotegravir to expand PrEP coverage among MSM in two contrasting North American cities
Abstract Introduction Long‐acting injectable cabotegravir (CAB‐LA) is superior to daily oral tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) for HIV pre‐exposure prophylaxis (PrEP) and could expand PrEP usage. Given price differentials between CAB‐LA and TDF/FTC, evaluating the…
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Journal Article
Research priorities for advanced HIV disease in Latin America and the Caribbean region: a modified Delphi study
Abstract Introduction Advanced HIV disease (AHD) remains a leading cause of mortality in Latin America and the Caribbean (LAC), driven by late diagnosis, treatment gaps and structural barriers, particularly among key populations and children. Persistent disparities in healthcare access, stigma, and…
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Journal Article
Estimates and predictors of HIV viral non‐suppression in South African adults on antiretroviral treatment
Abstract Introduction Viral suppression estimates are essential for monitoring the performance of HIV programmes. South Africa introduced dolutegravir (DTG)‐based antiretroviral therapy (ART) in 2019. We sought to generate updated estimates of viral suppression in South African adults on ART and…
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Journal Article
Behavioural and Structural Determinants of Mpox Vaccine Awareness and Uptake Among People With HIV in the Dominican Republic: A Cross‐Sectional Study
ABSTRACT Introduction Mpox disproportionately affects people with HIV (PWH), yet little is known about mpox vaccine awareness and uptake in low‐ and middle‐income countries. We evaluated mpox‐related knowledge, attitudes and practices (KAP) among PWH in the Dominican Republic to identify…
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Journal Article
Vaccination Coverage and Prevention Counselling for Vaccine‐Preventable STIs Among HIV PrEP Users in São Paulo, Brazil: A Retrospective Cohort Study
ABSTRACT Introduction HIV pre‐exposure prophylaxis (PrEP) users may be disproportionately vulnerable to sexually transmitted infections (STIs) in general, including several that are vaccine‐preventable. Understanding immunization patterns in this population is, therefore, crucial. However, data on…
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Journal Article
Defining the Efficacy of Meningococcal B Vaccines Against Gonococcal Acquisition: The Current Landscape
ABSTRACT Introduction Gonorrhoea is a major global sexually transmitted infection, with rising incidence and increasing antimicrobial resistance threatening current control strategies. If untreated, Neisseria gonorrhoeae can lead to severe reproductive health sequelae. Gonorrhoea is also linked to…
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Journal Article
From Awareness to Action Study: Improving Human Papillomavirus Knowledge, Screening and Vaccine Uptake Among Mother‐Adolescent Pairs in the HOMINY Study in Nigeria: A Longitudinal Study
ABSTRACT Introduction Persistent cervical infection with high‐risk human papillomavirus (HPV) in women is a leading cause of cervical cancer, and its co‐infection among people living with HIV increases the risk of other HPV‐associated cancers, including oropharyngeal and anogenital cancers. In…
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Journal Article
Mpox Vaccination and Diagnosis Among Sexual and Gender Diverse Populations in Brazil: Results From a Large Nationwide Online Survey
ABSTRACT Introduction Since the onset of the 2022 multinational mpox outbreak, Brazil has reported one of the highest case burdens globally, disproportionately affecting sexual and gender diverse populations. Mpox vaccination efforts in Brazil have been limited by delayed procurement, restricted…
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Journal Article
Durability of the Humoral Response to MPXV Infection
ABSTRACT Introduction Mpox virus (MPXV) re‐emerged in endemic countries in recent decades, resulting in large outbreaks in central and western Africa and a worldwide epidemic of clade IIb MPXV starting in 2022. Mpox cases in vaccinated persons, and a few documented reinfections, have raised…
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Journal Article
Potential Use of Neisseria meningitidis Serogroup B Vaccines to Prevent Neisseria gonorrhoeae Infection: Epidemiological Considerations
ABSTRACT Introduction Clinical trials are evaluating the efficacy of serogroup B meningococcal (MenB) outer membrane vesicle (OMV) vaccines in preventing gonorrhoea. We assessed the global epidemiology of gonorrhoea and MenB invasive meningococcal disease (IMD) and reviewed national MenB‐OMV…
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Journal Article
Potential Impact of Catch‐Up HPV Vaccination on HPV Prevalence and Cervical Cancer Incidence Among Women Living With HIV in South Africa: Results From Two Mathematical Models
ABSTRACT Introduction Women living with HIV (WLHIV) face an increased risk of cervical cancer (CC). With inequitable human papillomavirus (HPV) vaccine access globally and a programmatic focus on girls‐only school‐based delivery, many WLHIV in high HIV prevalence countries remain vulnerable to HPV…
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Journal Article
HIV low‐level viraemia: considerations for prevention and treatment in an era of highly effective and durable antiretroviral therapy regimens
Abstract Introduction Despite increasingly widespread acceptance of the (undetectable = untransmittable) U = U concept, uncertainty remains about the implications of suppressed viral loads (detected but ≤1000 copies/ml, also often referred to as low‐level viraemia) for both sexual HIV transmission…
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Journal Article
Optimizing the patient journey: Insights from early implementation of long‐acting cabotegravir and rilpivirine in four urban Ryan White‐funded clinics in the United States
Abstract Introduction Long‐acting injectable (LAI) cabotegravir/rilpivirine (CAB/RPV) represents a breakthrough in HIV treatment. However, understanding how to optimize real‐world service delivery and user experiences among people with HIV (PWH) remains limited. Methods Between August 2022 and…
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Journal Article
Intentions and attitudes of caregivers towards enrolment of their children and adolescents living with HIV into remission trials involving analytic treatment interruption
Abstract Introduction The development of approaches and interventions to achieve HIV remission continues to accelerate. Children living with HIV who started antiretroviral therapy (ART) at a young age and sustain viral suppression are an ideal clinical trial population. Trials may require analytic…
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Journal Article
The HIV/AIDS response as we knew it is over: Where do we go from here?
Abstract Introduction The global HIV response, once a model of progress and innovation, faces a profound moment. Despite four decades of pivotal scientific and programmatic advances—most notably in antiretroviral therapy (ART) and pre‐exposure prophylaxis (PrEP)—the world remains off track to meet…
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Journal Article
Age, sex—and what else? Rethinking priorities to close gaps in the HIV care cascade
Abstract Introduction Many countries with high HIV burden have made substantial progress towards UNAIDS 95‐95‐95 targets and ending AIDS, but gaps in some sub‐populations hinder overall achievement, even as programmes face potentially diminished resources. While certain broad groups defined by age…