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Italian Journal of Pediatrics
Scopus
ISSN 1824-7288 · BMC · 2,206 articles in the index
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Journal Article
Crossed cerebellar diaschisis in a COVID-19 patient with hemiconvulsion-hemiplegia syndrome: a case report and literature review
Abstract Background Crossed cerebellar diaschisis (CCD) is rare in patients with hemiconvulsion-hemiplegia syndrome (HHS). This report presents a novel and instructive case of CCD combined with HHS in a 7-month-old infant with coronavirus disease 2019 (COVID-19) and multisystem inflammatory…
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Journal Article
Extended NICUs or specialized pediatric networks? The need to reinforce centralized, multidisciplinary care – a comment on Decembrino et al.
Abstract The recent article by Decembrino et al. highlights the burden of RSV-related bronchiolitis admissions to Italian Neonatal Intensive Care Units (NICUs) during the 2021 season and proposes extending NICU roles to compensate for the national shortage of Pediatric Intensive Care Unit (PICU)…
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Journal Article
Diagnostic accuracy of MMBV in predicting bacterial infection in febrile children: a systematic review and meta-analysis
Abstract Background Distinguishing viral from bacterial infections in febrile children remains challenging despite available biomarkers. MMBV is a promising host-protein biosignature that computationally integrates TNF-related apoptosis-induced ligand, interferon-γ-induced protein-10, and…
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Journal Article
Risk prediction of encephalitis in hand, foot and mouth disease: a nomogram model based on platelet indices for resource-limited settings
Abstract Objective This study aimed to assess differences in peripheral blood platelet indices including platelet count (PLT), mean platelet volume (MPV), platelet distribution width (PDW), and the platelet-to-lymphocyte ratio (PLR) between children with hand, foot and mouth disease (HFMD)…
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Journal Article
Caregiving ability of parents of TBI children at discharge: status quo and derived care strategies
Abstract Background The rehabilitation and nursing care of children with traumatic brain injury (TBI) necessitate long-term caregiving, and the caregiving ability of parents exerts a critical influence on the prognosis of these children. This study was designed to analyze the current status of…
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Journal Article
Clinical features and analysis of the misdiagnosis of anomalous origin of the left coronary artery from the pulmonary artery in children
Abstract Background Anomalous left coronary artery from the pulmonary artery(ALCAPA) is a rare congenital cardiovascular malformation. The main manifestations are non-specific and prone to misdiagnose. Without active treatment, the prognosis is poor. The study summarized the clinical…
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Journal Article
Towards a shared diagnostic approach for pediatric short stature: a Delphi consensus of the Italian Society of Pediatrics and the Italian Society for Pediatric Endocrinology and Diabetology
Abstract Background Short stature is a common reason for referral in pediatric practice, but significant variability exists in diagnostic approaches and referral criteria. Therefore, the aim of this consensus was to improve the management of children with short stature through the knowledge and…
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Journal Article
Construction of a forest plot prediction model based on Lasso regression for Epstein-Barr virus associated hemophagocytic lymphohistiocytosis in children
Abstract Background To identify risk factors for the progression of Epstein-Barr virus(EBV) infection to Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis (EBV-HLH) and guide clinical intervention by analyzing the clinical data and laboratory examination between infectious…
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Journal Article
State of art of oral corticosteroids in children with acute asthma and wheezing
Abstract Background Oral corticosteroids (OCS) are widely used in the management of pediatric asthma exacerbations and recurrent wheezing. Despite their established efficacy, concerns about safety, optimal dosing, and appropriate clinical contexts persist. Methods This narrative review synthesizes…
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Journal Article
Ictal vomiting as the first manifestation of Tuberous Sclerosis Complex: report of two pediatric cases
Abstract Background Tuberous sclerosis complex (TSC) is a multisystem genetic disorder caused by pathogenic variants in TSC1 or TSC2, affecting approximately 1 in 6,000 live births. Diagnosis can be established genetically or clinically based on characteristic neurocutaneous, renal, and cardiac…
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Journal Article
Recent advancements in pediatric purulent meningitis: diagnosis and treatment
Abstract Purulent meningitis is a common disease of the central nervous system affecting children. It arises from various pathogens transmitted through diverse routes and can lead to significant sequelae, even death. The pathogenesis involves varying degrees of meningeal damage by pathogens…
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Journal Article
Survival in infants with trisomy 18, palliative care and ethical reflections: a single center considerations
Abstract Background Trisomy 18 was once considered a fatal diagnosis due to the presence of cardiac and extracardiac lesions. However, with the increasing use of therapeutic management, 3% to 25% of infants with trisomy 18 may survive beyond their first year, depending on the interventions…
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Journal Article
Clinical impact of targeted next-generation sequencing in paediatric pneumonia management: a real-world study evaluating diagnostic concordance and antimicrobial stewardship across multiple specimen types
Abstract Objective This study aims to evaluate the clinical utility of targeted next-generation sequencing (tNGS) in a real-world paediatric pneumonia cohort. Methods A retrospective cohort study was conducted of 586 children hospitalised with pneumonia who underwent tNGS testing alongside…
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Journal Article
Nutritional management of neonates who undergo major surgery for gastrointestinal disorders: a joint position paper of the Italian Society of Neonatology (SIN), the Italian Society of Pediatric Surgery (SICP), and the Italian Society of Pediatric Nutrition (SINUPE)
Abstract Neonates undergoing major gastrointestinal surgery for congenital or acquired disorders require complex nutritional management to support their growth and recovery. Prolonged fasting can be detrimental, necessitating timely and appropriate nutritional support. This joint position paper by…
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Journal Article
Pathogen trends and paradigm shifts of respiratory infections in children: a 5-year retrospective study from Perugia
Abstract Background Respiratory infections are one of the most common causes of morbidity and mortality among children. After the COVID-19 pandemic, the epidemiology of respiratory tract infections has changed and has been better traced by more frequent and less expensive molecular and antigenic…
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Journal Article
Cord blood cardiac markers and tissue doppler echocardiography findings in infants of diabetic mothers
Abstract Background Maternal diabetes mellitus (DM) significantly affects fetal cardiac and placental structure and function. This study aimed to assess structural and functional cardiac changes in infants of diabetic mothers (IDMs) using echocardiographic data and cord blood cardiac biomarkers…
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Journal Article
Digital media exposure and pediatric health: the recommendations from the Italian Society of Pediatrics Digital Dependency Commission
Abstract Background Digital media exposure has become an integral component of childhood and adolescence, profoundly reshaping developmental environments worldwide. The Italian Pediatric Society (SIP) Digital Dependency Commission aim to provide indications for families and paediatricians to…
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Journal Article
Off-label prescribing in pediatrics: between regulatory gaps and clinical evidence
Abstract Despite important regulatory progress, evidence supporting the use of medicines in children remains limited, and off-label prescribing continues to be common in pediatric practice. Regulatory initiatives such as the United States Pediatric Research Equity Act (PREA) and the European…
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Journal Article
Associations between lipid metabolism and Henoch–Schönlein purpura nephritis in children: a systematic review and meta-analysis
Abstract Background Henoch-Schönlein purpura (HSP)is the most common childhood vasculitis, and renal involvement (HSPN) significantly worsens its prognosis. Noninvasive correlates of renal involvement are therefore of interest. Dyslipidemia often coexists with renal inflammation. Clarifying this…
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Journal Article
Strategies for caffeine administration in preterm infants: route, dosing, monitoring, and adjunctive interventions - a systematic review
Abstract Introduction Caffeine is widely used in preterm infants, yet the optimal administration strategy remains unclear. This systematic review aims to evaluate different caffeine administration approaches, including route, frequency, dose modifications, and co-administration with surfactant in…
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