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Artery Research
Scopus
ISSN 1876-4401 · BMC · 3.125 artikel di indeks
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Artikel Jurnal
Gender-Based Patterns in Intracranial Aneurysm Site and Rupture Risk: A Single-Center Retrospective Cohort Study from the Caucasus region
Abstract Background Intracranial aneurysms (IAs) are vascular abnormalities characterized by localized dilation of cerebral arteries, with a higher prevalence in females. Ruptured IAs can lead to subarachnoid hemorrhage, a life-threatening condition. The purpose of this study is to investigate…
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Artikel Jurnal
Effect of Vitamin E Supplementation on Biomarkers of Endothelial Function in Adults: A GRADE-assessed Systematic Review and Dose-Response Meta-Analysis
Abstract Background and Objective Endothelial dysfunction is a central factor in the development of cardiovascular diseases. Serum adhesion molecules, including intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1), are important biomarkers of vascular health…
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Artikel Jurnal
Sex-Specific Association Between Lp-PLA2 and Arterial Stiffness: A Cross-sectional Study
Abstract Background Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a vascular-specific inflammatory enzyme implicated in atherosclerosis. However, its relationship with arterial stiffness and subclinical disease across sexes remains unclear in aging populations. Objective To investigate the…
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Artikel Jurnal
The Growing Burden of Lower Extremity Peripheral Artery Disease and its Attributable Risk Factors in the Eastern Mediterranean Region from 1990 to 2021
Abstract Background Lower extremity peripheral artery disease (LEPAD) is a progressive atherosclerotic condition. This study aims to elucidate the incidence, prevalence, disability-adjusted life years (DALYs) and death rates associated with LEPAD. Additionally, the attributable risk factors within…
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Artikel Jurnal
Cohort Profile: The Youth Vascular Consortium
Abstract Background Cardiovascular disease remains the leading cause of mortality worldwide, yet its origins lie in early life. Cardiovascular risk factors track from childhood into adulthood, and vascular abnormalities detected in youth predict future cardiovascular outcomes. Despite compelling…
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Artikel Jurnal
Adiposity, Lifestyle Factors, and Dilated Cardiomyopathy: A Two-Sample Mendelian Randomization Study
Abstract Background Observational studies have suggested strong correlations between obesity (as measured by body mass index [BMI]), lifestyle factors such as smoking, alcohol consumption, coffee intake, and insomnia, and dilated cardiomyopathy (DCM). However, the causal relationship between these…
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Artikel Jurnal
Exploring Genetic Association Between Gut Microbiota and Thoracic Aortic Aneurysms
Abstract Purpose Observational studies suggest a link between gut microbiota and thoracic aortic aneurysms (TAA), a blood vessel disease. However, whether this relationship reflects underlying genetic mechanisms remains unclear. Methods GWAS data for TAA, aortic diameter and gut microbiota were…
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Artikel Jurnal
Integrative Transcriptomic and Genetic Analysis Nominally Prioritizes SLC51A and TPMT as Candidate Diagnostic Genes for Thoracic Aortic Aneurysm
Abstract Background Thoracic aortic aneurysm (TAA) is a life‑threatening disease with limited blood‑based biomarkers for early detection and risk stratification. Integrating transcriptomic and genetic data may help identify potentially relevant genes and develop suggestive diagnostic tools. Methods…
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Artikel Jurnal
Cerebrovascular Responses During an Acute Bout of Resistance Exercise Do Not Differ Between Sex
Abstract Background Resistance exercise is recommended to reduce risk of cardiovascular and cerebrovascular disease, with evidence suggesting that women who engage in regular resistance exercise may receive a greater benefit than men. It is unknown whether acute resistance exercise elicits…
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Artikel Jurnal
Associations Between Cardiovascular Parameters and Functional Capacity, Physical Activity, and Quality of Life in Patients Undergoing Cardiac Rehabilitation
Abstract Introduction Cardiac rehabilitation (CR) is well established, but the relationship between cardiovascular parameters and health-related measures in patients with cardiovascular disease remains insufficiently characterized. In addition, evidence on immediate post-exercise cardiovascular…
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Artikel Jurnal
Deciphering the Role of Plasma Lipids in Pre-eclampsia and Eclampsia: Insights from Mendelian Randomization, Network Toxicology, and Molecular Dynamics Simulations
Abstract Objective This study aims to explore the mechanistic roles of the plasma lipidome in pre-eclampsia and eclampsia by integrating Mendelian randomization, network toxicology, and molecular dynamics simulation approaches. Methods Summary statistics for 179 lipid species, pre-eclampsia…
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Artikel Jurnal
Cardiac Workload in Kidney Transplant Recipients is Unchanged with Low-Intensity Resistance Training but Decreases with Standard Care: A Randomized Controlled Trial
Abstract Background Hypertension remains a major concern in kidney transplant recipients, in part due to the detrimental effects of standard care immunosuppressive therapy. Although resistance training appears safe and may reduce aortic stiffness in kidney transplant recipients, it lacks consistent…
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Artikel Jurnal
Causal Relationship Between Circulating Plasma α-Klotho Levels and Myocardial Fractal Dimension
Abstract Background Myocardial fractal dimension (FD), a marker of myocardial microarchitecture, correlates with cardiac remodeling. The molecular mechanisms linking α-Klotho, a circulating anti-aging protein, to myocardial FD remain unclear. This study investigates the causal relationship between…
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Artikel Jurnal
What do Healthcare Professionals Think About Vascular Ageing and Why it is Not Measured in Clinical Practice? A Study by VascAgeNet
Abstract Background Cardiovascular disease (CVD) is a major global health challenge. Vascular ageing assessment can identify high-risk individuals for effective prevention, but the knowledge, awareness, perceptions, applications, and limitations of vascular ageing assessment in clinical and…
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Artikel Jurnal
Fitness After Stroke Trial (FAST): Protocol for a Preliminary Efficacy Study of Recumbent Stepper High-Intensity Interval Training
Abstract Background Cardiorespiratory fitness and vascular health are significantly impaired post-stroke. High-intensity interval training (HIIT) has emerged as a promising strategy to improve walking in people with chronic stroke, but broadly integrating HIIT into stroke recovery remains limited…
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Artikel Jurnal
One Size Does Not Fit All: From Blood Pressure Reduction to Personalised Modulation of Arterial Stiffness in Hypertension—An Extended Review Resulting From the ARTERY Career Development Lecture Award 2025
Abstract This article is an extended review which arises from the ARTERY Career Development Lecture Award 2025 (Valencia, Spain) and reflects my scientific trajectory as a clinical academic pharmacist working at the interface of vascular physiology, pharmacology, and translational hypertension…
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Artikel Jurnal
Programmed Cell Death: A Key Pathway in Intracranial Aneurysm Progression
Abstract Intracranial aneurysm (IA) is a common cerebrovascular disease characterized by abnormal bulging of the intracranial arterial wall, with high potential risk of rupture and severe clinical consequences. As a major subtype of IAs, middle cerebral artery aneurysm (MCAA) accounts for 30%–40%…
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Artikel Jurnal
Exploring the Link Between Markers of Arterial Health and Urinary Dopamine in South African Adults: The SABPA Study
Abstract Background Urinary dopamine enhances blood pressure (BP) regulation by promoting natriuresis, vasodilation, and anti-inflammatory effects while lowering renal oxidative stress. Ethnicity-related differences in sodium handling, sympathetic activity, and subsequently…
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Artikel Jurnal
Effects of Aerobic Training on Cardiorespiratory Fitness in Middle Aged Adults with Endothelial Dysfunction
Abstract Objectives High cardiorespiratory fitness is a vital part of cardiovascular prevention in health and disease. However, the optimal age of aerobic exercise interventions is unclear and animal studies suggest a blunted effect of training on cardiorespiratory fitness with a priori endothelial…
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Artikel Jurnal
Effect of Melatonin and Melatonin Receptor agonist Supplementation on Vascular Stiffness: A Systematic Review and Meta-analysis
Abstract Background Arterial stiffness is a critical precursor to clinical cardiovascular disease. This systematic review and meta-analysis aimed to evaluate the impact of melatonin and its receptor agonists on markers of arterial stiffness and hemodynamic parameters in adults. Methods A…
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