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Brain Stimulation
Scopus
ISSN 1935-861X · Elsevier · 4,517 articles in the index
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Journal Article
Non-invasive modulation of brain activity and behavior by transcranial radio frequency stimulation
Background: Achieving non-invasive, targeted modulation of deep brain tissue remains a major challenge in neurotechnology. Current non-invasive brain stimulation methods—such as transcranial electrical (TES), magnetic (TMS), and focused ultrasound (TFUS) stimulation—suffer from limitations in…
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Journal Article
Electroconvulsive stimulation elicits antidepressant-like effects via βCaMKII-dependent lateral habenula modulation
Background: Electroconvulsive therapy (ECT) remains a highly effective intervention for acute episodes of major depressive disorder, offering rapid and robust antidepressant effects. However, its underlying mechanisms remain unclear, as prior studies focusing on conventional brain regions (e.g…
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Journal Article
Unilateral online ultrasound stimulation of early visual cortex suppresses responses to contralateral visual stimuli
Introduction: Transcranial ultrasound stimulation (TUS) shows great promise for inducing neuroplastic changes that persist long after stimulation. Evidence of stimulation-locked (online) neural changes would enable the development of closed-loop application of TUS. However, such responses have been…
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Journal Article
Trigeminal nerve direct current stimulation modulates raphe–hippocampal network synchrony in rats
Background: Trigeminal nerve stimulation is a promising noninvasive method to modulate subcortical circuits involved in cognition. This study investigated the influence of trigeminal nerve direct current stimulation (TN-DCS) on neuronal activity and coherence between the raphe nuclei and…
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Journal Article
Modulation of motor cortical theta and gamma oscillations using phase-targeted, closed-loop optogenetic stimulation of local excitatory and inhibitory neurons
Theta and gamma oscillations are prominent features of cortical local field potentials (LFPs) and stimulation of the motor cortex at these frequencies can enhance motor learning. Phase-targeted closed-loop stimulation could provide a more precise and effective method to modulate these oscillations…
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Journal Article
Tractography-guided versus clinical contact selection for deep brain stimulation in tremor - A prospective clinical trial
Background: Imaging-guided programming strategies for deep brain stimulation (DBS) offer the potential to reduce programming time and complexity. However, evidence-based paradigms tailored to tremor remain unavailable. Converging research points to an involvement of the dentato-rubro-thalamic tract…
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Journal Article
Network-targeted TMS modulates nicotine craving and default mode network connectivity in psychotic disorders
Objective: Tobacco use is the top preventable cause of early mortality in schizophrenia, but the underlying pathophysiology remains unknown. In schizophrenia, small studies have linked default mode network (DMN) organization to tobacco use and showed that nicotine normalizes DMN disorganization. We…
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Journal Article
Transcutaneous vagus nerve stimulation enhances episodic memory across valences and memory stages
Background: Transcutaneous auricular vagus nerve stimulation (taVNS) is a promising non-invasive neuromodulation technique with the potential to enhance memory. However, the optimal timing of stimulation across memory stages—encoding, consolidation, and retrieval—remains unclear. Objective: This…
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Journal Article
Effect of electroconvulsive therapy on neural oscillations in schizophrenia: A magnetoencephalography resting-state study
Objective: Schizophrenia is a complex, chronic mental disorder, and pharmacologic treatment alone is often insufficient. Electroconvulsive therapy (ECT) is a rapid-acting and widely employed physical intervention for schizophrenia, yet its underlying mechanisms remain elusive. The present study…
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Journal Article
Optimizing and assessing multichannel TMS focality
Background: Multichannel transcranial magnetic stimulation (mTMS) enables electronic steering of induced electric fields across multiple cortical targets without physical coil repositioning, addressing key limitations of conventional single-channel TMS (sTMS). However, determining optimal input…
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Journal Article
Neural mechanisms of tDCS: Insights from an in-vivo rodent model across a range of electric field strengths
Background: Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation technique that uses low-amplitude currents to generate low electric fields in the brain, influencing cognition, motor skills, and behavior. Despite its potential, the neural mechanisms underlying tDCS…
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Journal Article
Vagus nerve stimulation exerts disease-modifying effects in epileptic rats by enhancing hippocampal adenosine signalling
Objectives: Vagus nerve stimulation (VNS) is an established neuromodulatory therapy for refractory epilepsy, but its disease-modifying mechanisms remain unclear. Adenosine is an endogenous anticonvulsant and a key regulator of epileptogenesis, and adenosine kinase (ADK) controls extracellular…
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