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Indonesian Journal of Cancer
ISSN 1978-3744 · Dharmais Cancer Hospital - National Cancer Center · 726 artikel di indeks
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Artikel Jurnal
Mammary Paget’s Disease in a 46-year-old Woman with Ductal Carcinoma in Situ (DCIS): A Case Report
Background: Mammary Paget’s disease (MPD) accounts for 1—4% of all breast carcinomas. It can affect both men and women with a wide age range, 27 to 88 years old, and 20—30% affect premenopausal woman. Moreover, no specific risk factor has been identified for MPD, and the exact pathogenesis remains…
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Non-Down Syndrome Acute Megakaryoblastic Leukemia with KMT2Ar/MLL Rearrangement: A Case Report
Introduction: Non-Down syndrome acute megakaryocytic leukemia (Non-DS-AMKL) is a rare leukemia. Pediatric acute myeloid leukemia (AML) accounts for only 4—15% of all leukemia cases, while AMKL accounts for only 3-10% of pediatric AML. Most AMKLs are Down syndrome (DS) (> 75%). Diagnostic criteria…
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A Pediatric Case of Desmoplastic Nodular Medulloblastoma: A Case Report and Literature Review
Background: Desmoplastic nodular medulloblastoma (DNMB) is an uncommon but malignant variant of medulloblastoma that typically occurs in children. Although it is malignant in nature, children with DNMB have a high 5-year overall survival rate. Here, we present a complex case of a DNMB in a…
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Artikel Jurnal
Effect of Hormonal Therapy Type, Treatment Duration, and Menopausal Status on Lipid Profiles in Breast Cancer Patients
Background: Hormonal therapy is widely used in breast cancer treatment, yet its long-term effects on lipid profiles remain a concern, especially regarding the duration of treatment. This study aimed to analyze the association between the type and duration of hormonal therapy and changes in lipid…
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Artikel Jurnal
High-Grade Polymorphous Adenocarcinoma Mimicking Salivary Duct Carcinoma: A Diagnostic Challenge
Introduction: Polymorphous adenocarcinoma (PAC) is a rare, low-grade malignancy primarily arising in the minor salivary glands, accounting for 1-6% of head and neck tumors. It commonly affects the palate, but can rarely manifest in major salivary glands, such as the parotid gland. Although…
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Artikel Jurnal
The Effectiveness of Glacial Acetic Acid and 95% Alcohol in Lysing Blood-Contaminated Liquid-Based Cervical Cytology Specimens
Background: Liquid-based cervical cytology is a monolayer slide preparation technique that enhances the accuracy of conventional Pap smears. Blood contamination (erythrocytes) is one of the most common causes of inadequate liquid-based cervical cytology samples. Therefore, alternative methods and…
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Artikel Jurnal
Statins and Survival in Castration-Resistant Prostate Cancer After Abiraterone or Enzalutamide: A Systematic Review
Background: Prostate cancer is the second most commonly diagnosed cancer in men worldwide and a leading cause of cancer-related mortality. Castration-resistant prostate cancer (CRPC) develops despite androgen deprivation therapy (ADT), often after treatment with abiraterone or enzalutamide. Statins…
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Implementation of Cancer Patient Navigation in Various Countries: A Scoping Review
Background: The increasing incidence of cancer has led to growing challenges in the provision of cancer patient care. To address these challenges, cancer patient navigation (CPN) has been developed and implemented in various countries with different models and approaches. This scoping review aims…
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Exploring the Key Factors Influencing Survival in Pediatric Acute Lymphoblastic Leukemia: A Literature Review
Acute lymphoblastic leukemia (ALL) is a hematologic malignancy characterized by the uncontrolled proliferation of immature B-cell or T-cell lymphoid progenitors. This malignancy predominantly affects children, with a peak incidence between the ages of 2 and 5 years. Data from Indonesia show an…
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Artikel Jurnal
Current Findings in the Resistance Mechanism of Anti-CD19 CAR T-Cell Therapy in B-Cell Malignancies: A Literature Review
Background: Chimeric Antigen Receptor T-cell (CAR T-cell) therapy targeting CD19 on B-cells has emerged as a promising treatment for B-cell malignancies such as B-Acute Lymphoblastic Leukemia (B-ALL) and Diffuse Large B-cell Lymphoma (DLBCL). Despite its success, resistance mechanisms, including…
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Artikel Jurnal
The Effect of Curcumin, Piperine, and Taurine Combination in Hepatocellular Carcinoma Patients: A Systematic Review and Meta-Analysis
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death and the sixth most diagnosed cancer. Curcumin (C) has anticancer effects toward HCC and may enhance the antitumor effects of certain traditional chemotherapeutic and molecular target drugs. Co administration with piperine (P)…
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Artikel Jurnal
Diagnostic Challenge of Acute Lymphoblastic Leukemia (ALL)-L2 in an Adult: A Case Report
Introduction: Acute lymphoblastic leukemia (ALL) is one of the rare hematologic malignancies that commonly occurs in children and less commonly in adults. The prior cases reported adults with ALL were having varied clinical manifestations, which sometimes confused the physicians. Additionally…
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Artikel Jurnal
Effective Use of Transarterial Chemoembolization (TACE) in an 8-Month-Old Infant with Hepatoblastoma PRETEXT III: A Case Study
Introduction: Hepatoblastoma (HB) is a rare primary malignant tumor of the liver in children. Treatment procedures for HB usually involve surgery and even liver transplantation, in addition to neoadjuvant or palliative systemic chemotherapy. However, the recent development of transarterial…
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Artikel Jurnal
The Role of Age in Breast Cancer Prognosis and Biomarker Expression among Chemotherapy Patients
Background: Breast cancer is the most common malignancy among women worldwide, representing a significant public health problem due to its high incidence and mortality rates. Among various prognostic factors, age has been inconsistently reported in the literature, despite its potential biological…
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Artikel Jurnal
Clinical Characteristics and Length of Stay of Lung Cancer With Pleural Effusion at Primary Referral Center Hospital in Aceh
Background: Lung cancer is the leading cause of death worldwide, with the most common complication being pleural effusion. This complication is often associated with poor outcomes and has a significant impact on treatment duration in the hospital. Therefore, this study aimed to assess the clinical…
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Artikel Jurnal
The Effect of Papaya—Lime Smoothie (Carica papaya L. & Citrus aurantiifolia) on Constipation Severity in Breast Cancer Patients Undergoing Chemotherapy
Background: Constipation is a common gastrointestinal complication among cancer patients undergoing chemotherapy, negatively affecting quality of life and treatment adherence. Non pharmacological interventions such as fruit-based dietary strategies may provide a safe and accessible alternative…
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Artikel Jurnal
Overall Survival of Oral Cancer Patients: A Retrospective Study in Dharmais National Cancer Center Hospital
Background: Oral cancer ranks as the 16th most common malignancy, with a disproportionately higher incidence in Asia. The 5-year overall survival (OS) of oral cancer shows differences in many countries. In Indonesia, many patients present at advanced stages, making adequate surgery followed by…
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Artikel Jurnal
Sonoelastography Findings in Breast Cancer: Correlation with Molecular Subtypes and Ki-67 Expression
Background: Strain elastography is increasingly used as a complementary imaging tool to assess suspicious breast lesions by evaluating tissue stiffness using the strain ratio and elastography score. Owing to the intertumor heterogeneity of breast cancer, this study aimed to investigate the…
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Artikel Jurnal
The Role of Ultrasound in Predicting Malignancy in Ovarian Neoplasm: A Case Report
Background: Ovarian neoplasm is associated with the highest mortality rate compared to other gynecologic cancers. Unfortunately, non-specific symptoms and a lack of a reliable screening approach have led to failure in detecting most cases early. At present, there is an ongoing challenge in…
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Artikel Jurnal
Case Series of Preserving Ankle Stability After Giant Cell Tumor Resection in the Lateral Malleolus: Role of Fibular Head Autograft
Background: Giant Cell Tumor (GCT) is a non-metastatic bone tumor known for its local aggressiveness and recurrence risk. While commonly affecting the knee and distal radius, involvement of the distal fibula, particularly the lateral malleolus, is extremely rare. Standard surgical approaches may…