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Journal of Oral Microbiology
Scopus
ISSN 2000-2297 · Taylor & Francis Group · 867 artikel di indeks
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Artikel Jurnal
An innovative microplate-based method to measure coaggregation between a model pair of coaggregating oral bacteria
Background Coaggregation is proposed to enhance oral biofilm development. This study aims to evaluate an innovative high-throughput spectrophotometric method for quantifying coaggregation, which relies upon dome-shaped wells (DSWs) in microplates to partition coaggregates in cell suspensions, and…
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Subgingival microbiome and adjunctive use of probiotics in the treatment of periodontitis in patients with diabetes: a secondary analysis of a randomized clinical trial
Background Adjunctive therapies have been proposed to enhance periodontal outcomes by modulating the subgingival microbiome. However, the microbiological effects of probiotic supplementation in diabetic patients with periodontitis remain unclear, particularly when assessed using high-resolution…
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Antimicrobial susceptibility testing of Aggregatibacter Actinomycetemcomitans can be performed using the EUCAST medium for anaerobic bacteria
Background The oral bacterium Aggregatibacter actinomycetemcomitans (Aa) is associated with infectious diseases treated with antibiotics, but specific recommendations for antimicrobial susceptibility testing (AST) of the species do not yet exist. Objective To evaluate the possibility to perform AST…
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Characteristics of Candida albicans metabolism of glucose and two sugar substitutes, xylose and xylitol and effect of these substitutes on glucose metabolism from a cariogenic perspective
Objectives Carbohydrate metabolism and subsequent acid production of Candida albicans remain insufficiently understood. C. albicans may utilize xylitol, but its cariogenic implications are understudied. This study examined growth and metabolism of glucose, xylitol and precursor xylose by C…
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Interrogation of imaging-based interspecies dynamics in the oral microbiome
Background The oral cavity presents a highly dynamic environment where inter-microbial communications play a pivotal role. Understanding the spatial organization of microbial ecosystems has been highlighted on the microbiome and polymicrobial infection. Furthermore, cross-feeding and modulation by…
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Human papilloma virus (HPV) infection associated with cyclosporine-induced gingival overgrowth in renal transplant recipients
Introduction Immunosuppressive drugs may lead some individuals to develop gingival overgrowth abnormalities, which may be associated with HPV infection.Objective This study investigated the frequency of HPV subtypes in renal transplant recipients (RTRs) and healthy volunteers (HC) to evaluate the…
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Denture-associated oral microbiome in dentate and edentulous older adults living in long-term care facilities
Background The denture-associated oral microbiome (DAOM) may act as reservoirs of pathogenic microorganisms with potential health effects.Objectives To characterize the compositional and functional activity of the DAOM in dentate and edentulous older adults residing in long-term care facilities…
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Supragingival Actinomyces naeslundii aggravates metabolic dysfunction-associated fatty liver disease via the oral–gut axis
Background Metabolic dysfunction-associated fatty liver disease (MAFLD) is the most prevalent chronic liver disease but lacks effective therapies. Oral microbial dysbiosis is closely associated with metabolic dysfunction.Objective This study aimed to delineate MAFLD-specific oral microbiota…
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P. gingivalis induces endothelial dysfunction via mitochondrial fission dependent VDAC1-HK2 disassociation
Background Mitochondrial dysfunction contributes to Porphyromonas gingivalis (P. gingivalis)-impaired endothelial function. Given the critical role of the mitochondrial permeability transition pore (mPTP) in mitochondrial homeostasis, this study explored how P. gingivalis promotes dynamin-related…
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Shotgun metagenomic analysis of the tongue-coating microbiome reveals oral microbes and their functions in older adults with dementia
Introduction Dementia poses a growing burden in the aging population, prompting the search for noninvasive biomarkers for early detection.Materials and methods We performed shotgun metagenomic sequencing of tongue-coating samples from older adults with dementia (n = 30) and cognitively healthy…
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Planetary health diet with einkorn as a potential preventive strategy to improve interdental microbiota, oral health and quality of life: a pilot clinical trial
Background Non-communicable diseases (NCDs) involve chronic inflammatory mechanisms to which periodontal periodontal dysbiosis may contribute. The Planetary Health Diet (PHD), a sustainable plant-based model for NCD prevention remains poorly explored regarding its impact on the interdental…
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A comparative study on arginine metabolism by oral streptococci revealed both divergence and heterogeneity in dependence on arginine and significance of ornithine and citrulline
Background Current understanding in arginine metabolism by streptococci is limited in species and strains.Objectives We compared the ability of several abundant oral streptococci to synthesize and assimilate arginine.Design Multiple species of oral streptococci and their genetic mutants were…
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Comparative effects of periodontitis – versus periodontal health-derived saliva on systemic lipid metabolism in mice: mediation through oral–gut axis
Background Periodontitis is linked to dyslipidaemia, but the mechanism still requires further investigation.Objective This study aimed to investigate the periodontitis-dyslipidaemia interplay, comparing the impact of periodontitis-associated versus healthy salivary microbiota on systemic lipid…
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Pulpitis as a microbial disease: single-cell insights into host responses and diagnostic biomarkers for vital pulp therapy
Background Pulpitis is a common dental disease driven by complex microbial infections, yet its microbial origins, diversity, and pathogenic mechanisms remain incompletely understood. A major clinical challenge is the absence of objective biological criteria to assess the severity and reversibility…
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Streptococcus dentisani 7746 encodes a cocktail of 14 bacteriocins associated with Com and Blp-like quorum sensing regulatory systems
Aim We explored in silico and in vitro the complete bacteriocin profile of the oral probiotic Streptococcus oralis subsp. dentisani strain 7746 with the primary objective of providing a descriptive analysis of bacteriocin genomic organization, regulatory context, and transcriptional…
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Association between diet quality and the oral microbiome in three US cohort studies
Background The oral microbiome has been associated with overall health, but the contribution of dietary habits to oral microbial composition is not well understood.Objective We evaluated the association between diet quality (Healthy Eating Index [HEI] 2015) and the oral microbiome in the…
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Macrophage activation and invasion by P. gingivalis is modulated by PPAD and accessory fimbriae subunits
Background Porphyromonas gingivalis is a master manipulator of host immune responses in the periodontium. Peptidyl arginine deiminase (PPAD), a recently identified virulence factor of P. gingivalis, responsible for citrullination of both host- and bacterium-derived proteins and peptides, also plays…
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Artikel Jurnal
The oral microbiome as a regulatory hub for systemic health: a systematic review of mechanistic links and clinical implications
Background The human oral microbiome is a highly diverse ecosystem with important roles in oral and systemic health. Beyond dental caries and periodontitis, oral dysbiosis has been increasingly implicated in the development of multiple non-communicable diseases.Objective To systematically…
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Artikel Jurnal
Effects of Berberine chloride hydrate on cariogenic multispecies streptococcal biofilm
Background Dental caries, a bacterial infectious disease related to biofilm, occurs due to an increase in the proportion of cariogenic bacteria over that of commensal bacteria. This study aimed to create an in vitro biofilm model consisting of S. sanguinis, S. gordonii, and S. mutans to study the…