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Korean Journal of Anesthesiology
Scopus
ISSN 2005-6419 · Korean Society of Anesthesiologists · 2,312 articles in the index
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Human placental mesenchymal stem cell-derived exosomes carrying hsa-let-7i-5p mitigate lung injury in a murine model of aspiration pneumonia
Background Aspiration pneumonia (AP), which can be caused by gastric content inhalation into the lower airways, causes acute lung injury (ALI) through complex mechanisms, including inflammation, oxidative stress, and apoptosis. Here, we evaluated the efficacy of exosomes derived from human…
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Human placental mesenchymal stem cell for the treatment of lung injury
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Do fascial plane blocks improve respiratory function after breast surgery?
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Impact of ultrasound-guided rhomboid intercostal and serratus anterior plane blocks on respiratory function after modified radical mastectomy: a randomized controlled trial
Background This study aimed to evaluate the effectiveness of the rhomboid intercostal plane (RIP) and serratus anterior plane (SAP) blocks at enhancing respiratory function in patients undergoing modified radical mastectomy (MRM). Methods Patients were randomly assigned to the block or control…
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Perioperative metformin use in noncardiac surgery: moving beyond precautionary discontinuation
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Association of preoperative metformin use with postoperative mortality and morbidity in type 2 diabetes patients undergoing noncardiac surgery: a retrospective cohort study
Background Diabetes mellitus (DM) is prevalent among adults, many of whom require surgical interventions. Although metformin may improve postoperative outcomes by reducing inflammation, its effects on postoperative mortality and complications remain unclear. This study aimed to determine whether…
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Changes in pulse wave transit time variability after interscalene brachial plexus block placement
Background The pulse wave transit time (PWTT) increases with decreased vascular tone resulting from sympathetic blockade caused by regional anesthesia. It oscillates, exhibiting variability due to the interaction between the autonomic nervous and cardiovascular systems. We hypothesized that…
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Impact of neuromuscular blockade depth on postoperative systemic cytokine release: a systematic review and meta-analysis
Background Deep neuromuscular blockade (NMB) optimizes surgical conditions, particularly during laparoscopic procedures. However, its effects on systemic cytokines associated with anesthesia-related complications, including postoperative delirium and cognitive dysfunction, remain unclear. In this…
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Efficacy of pectoral nerve II block for flap dissection-related pain following robot-assisted transaxillary thyroidectomy: a prospective, randomized controlled trial
Background Robot-assisted transaxillary thyroidectomy (RATT) involves extensive flap dissection, leading to significant postoperative pain. This study evaluated the efficacy of pectoral nerve II (PECS II) block in pain relief, opioid reduction, and recovery enhancement. Methods This prospective…
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Three-dimensional bioprinting in drug delivery: a broad-spectrum review
Three-dimensional (3D) bioprinting has emerged as a transformative technology for drug delivery that offers anatomically customized, spatially controlled, and programmable release systems. These innovations hold significant promise in the fields of anesthesiology and pain medicine, particularly for…
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Key strategies in trauma anesthesia for severe hemorrhage: a narrative review
Trauma anesthesia demands a high level of expertise. In this context, anesthesiologists are required to manage complex physiology and rapidly evolving scenarios in critically injured patients, who often present profound hemodynamic instability. In addition to providing intraoperative anesthesia…
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Evolving perspectives on blood transfusion in obstetric hemorrhage: a narrative review
Globally, postpartum hemorrhage is still among the most significant factors in preventable maternal morbidity and mortality. Although early recognition and intervention have improved with advances in obstetric care, transfusion practices are often based on fixed thresholds that may not accurately…
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Insulin augments vasodilatory response elicited by amlodipine via nitric oxide-dependent vasodilation in isolated rat aortas
Background High-dose insulin and euglycemic therapy are widely used to treat calcium channel blocker toxicity. However, the effect of insulin on vasodilation evoked by the dihydropyridine calcium channel blocker amlodipine remains unknown. This study examined the effect of insulin on…
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Analgesic mechanism of Panaphix in spinal nerve-ligated rats: involvement of microglial inflammatory cytokines
Background Neuropathic pain, a chronic and debilitating condition caused by damage to the nervous system, remains challenging to treat due to its complex pathophysiology and resistance to analgesics. This study investigated the analgesic effects of Panaphix (PAX-1), a novel pharmacological agent…
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Severe bradycardia in a child with an implanted vagus nerve stimulator undergoing laparoscopy -A case report-
Background Vagus nerve stimulation is an established therapeutic option for children with drug-resistant epilepsy who do not respond to other treatments. During surgical procedures, this therapy has various anesthetic implications and may result in critical respiratory and cardiac complications…
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From association to causation: interpreting PS-based analyses in real-world evidence
Propensity score (PS) methods are widely used in real-world evidence studies to reduce confounding and to approximate randomized comparisons. However, statistical adjustment is often misinterpreted as evidence of causality, leading to overgeneralization and inappropriate clinical conclusions. In…
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Cadaveric investigation of an ultrasound-guided obturator canal approach for obturator nerve block
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