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Journal

Journal of Cardiovascular and Thoracic Research

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ISSN 2008-5117 · Tabriz University of Medical Sciences · 654 articles in the index

  1. Journal Article Full text

    Ruptured mitral valve aneurysm in a patient with immunodeficiency and chronic renal failure

    Mustafa Kamil Yemis; Saadet Guven; Ozgur Can Usta et al.

    Journal of Cardiovascular and Thoracic Research, Vol. 18 No. 1 · 2026 · English · DOAJ Scopus

    Mitral valve aneurysm; defined as a bulge of the mitral valve leaflet toward the left atrium is a rare abnormality whose pathophysiology is poorly understood. The weakened aneurysmal wall may rupture and may cause severe mitral regurgitation and life-threatining conditions. In this case report we…

  2. Journal Article Full text

    Application of spectral CT in coil embolization treatment of bronchial artery aneurysm: A case report

    Shanshan Zhang; Tao Hu; Langzhou Fu et al.

    Journal of Cardiovascular and Thoracic Research, Vol. 18 No. 1 · 2026 · English · DOAJ Scopus

    We report a case of a bronchial artery aneurysm accompanied by a bronchial artery to pulmonary artery fistula in which only coil embolization was performed. Post-embolization, the majority of patients face significant metal artifacts from stents or coils during routine CT scans, which can…

  3. Journal Article Full text

    Role of left ventricular strain measurements and native T1 and T2 mapping on cardiac magnetic resonance imaging in evaluating early left ventricle myocardial derangement in patients with high normal blood pressure

    Rishabh Khurana; Priya Jagia; Vineeta Ojha et al.

    Journal of Cardiovascular and Thoracic Research, Vol. 18 No. 1 · 2026 · English · DOAJ Scopus

    Introduction: The study sought to evaluate changes in left ventricular (LV) strain and native T1/T2 mapping characteristics on cardiac magnetic resonance imaging (CMR) in patients with high-normal blood pressure (HNBP). Methods: A prospective case-control study including 25 cases having HNBP and 25…

  4. Journal Article Full text

    Exploring cardiovascular risk in subclinical hypothyroidism: The impact of TSHR gene expression and systemic biomarkers

    Manjusha Kottola; Desigamani Kanniyappan; Damodaran Boopathi et al.

    Journal of Cardiovascular and Thoracic Research, Vol. 18 No. 1 · 2026 · English · DOAJ Scopus

    Introduction: Subclinical hypothyroidism (SCH), defined by elevated thyroid-stimulating hormone (TSH) with normal thyroid hormone levels, affects approximately 3–8% of the population. Growing evidence indicates that thyroid-stimulating hormone receptor (TSHR) expression in cardiovascular tissues…

  5. Journal Article Full text

    Mid-term outcomes associated with thoracic endovascular aortic repair and differences in outcomes for thoracic aortic aneurysms versus type B aortic dissections

    Taiwo Dodo-Williams; Daniel Willie-Permor; Shima Rahgozar et al.

    Journal of Cardiovascular and Thoracic Research, Vol. 18 No. 1 · 2026 · English · DOAJ Scopus

    Introduction: Thoracic endovascular aortic repair (TEVAR) has become the preferred treatment modality of thoracic aortic pathologies. Since survival outcomes are influenced by disease acuity and pathology, we aim to compare mid-term outcomes of TEVAR in the management of thoracic aortic aneurysms…

  6. Journal Article Full text

    Elevated asprosin levels in epicardial adipose tissue: Implications for coronary artery disease

    Hossein Shateri; Babak Manafi; Amir Hossein Yazdi et al.

    Journal of Cardiovascular and Thoracic Research, Vol. 18 No. 1 · 2026 · English · DOAJ Scopus

    Introduction: This study investigates the role of the adipokine asprosin in coronary artery disease (CAD) by comparing its levels in epicardial adipose tissue (EAT) and serum between individuals with and without CAD. Asprosin is known to be involved in conditions such as insulin resistance and…

  7. Journal Article Full text

    Beyond calories: the effect of meal patterns on obesity risk in the IRanian National Obesity Registry

    Mina Nosrati; Niosha Samadi; Ali Mottaghi Moghadam Shahri et al.

    Journal of Cardiovascular and Thoracic Research, Vol. 18 No. 1 · 2026 · English · DOAJ Scopus

    Introduction: The prevalence of obesity is increasing. Eating habits are modifiable factors that may be effective in reducing obesity. We aimed to investigate the relationship between meal frequency and daily breakfast and the presence of obesity. Methods: A total of 4137 overweight and obese…

  8. Journal Article Full text

    ACE/ACE2 axis in cardiovascular disease and COVID-19: Molecular insights and therapeutic perspectives

    Sony Peter; Thiruchenduran Mohana; Dhanavel Anandhi et al.

    Journal of Cardiovascular and Thoracic Research, Vol. 18 No. 1 · 2026 · English · DOAJ Scopus

    The renin-angiotensin system (RAS) plays a central role in regulating blood pressure and cardiovascular health. Angiotensin-converting enzyme (ACE) facilitates the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor that contributes to hypertension and heart failure. Conversely…

  9. Journal Article Full text

    Comparing mitral transcatheter edge-to-edge repair and surgical intervention in mitral regurgitation: A meta-analysis

    Emídio Mata; Barbara Lage Garcia; Margarida Castro et al.

    Journal of Cardiovascular and Thoracic Research, Vol. 18 No. 1 · 2026 · English · DOAJ Scopus

    Surgery remains the standard treatment for severe mitral valve regurgitation (MR), but growing evidence highlights the potential role of mitral valve percutaneous edge-to-edge repair (M-TEER). This meta-analysis aims to compare 12-month all-cause mortality between M-TEER and surgical intervention…

  10. Journal Article Full text

    Primary cardiac angiosarcoma - a diagnostic roller-coaster till fatality

    Bhupendra Kumar Sihag; Ajay Bahl; Sarthak Wadhera et al.

    Journal of Cardiovascular and Thoracic Research, Vol. 17 No. 2 · 2025 · English · DOAJ Scopus

    A 28-year-old male with a relatively short history of progressive dyspnea and a large pericardial effusion with tamponade was found to have an intracardiac mass localized in right atrium (RA) on echocardiography. Multimodality imaging revealed an irregular mass abutting the lateral wall of RA, with…

  11. Journal Article Full text

    Influence of isolated coronary artery bypass graft on moderate functional mitral regurgitation

    Hakimeh Sadeghian; Babak Oloomi; Seyed Hossein Ahmadi Tafti et al.

    Journal of Cardiovascular and Thoracic Research, Vol. 17 No. 2 · 2025 · English · DOAJ Scopus

    Introduction: The natural course and clinical significance of moderate mitral regurgitation (MR) in patients undergoing isolated coronary artery bypass graft (CABG) surgery are still debated. This study aimed to determine the course of moderate functional MR after CABG. Methods: In this…

  12. Journal Article Full text

    Intraoperative transit time flowmetry during off-pump coronary artery bypass grafting: Early outcome of two different anastomosis technique

    Abdusalom Abdurakhmanov; Shahboz Buranov; Farkhod Mamataliev et al.

    Journal of Cardiovascular and Thoracic Research, Vol. 17 No. 2 · 2025 · English · DOAJ Scopus

    Introduction: Intraoperative transit time flowmetry (TTF) is an essential technique for evaluating graft function during off-pump coronary artery bypass grafting (OPCABG). This study compares graft quality and outcomes using TTF in two surgical approaches: sequential and Y-type saphenous vein…

  13. Journal Article Full text

    Reduction of maximal false lumen area ratio by interactive cannulation perfusion in DeBakey type I acute aortic dissection repair

    Qin Jiang; Shanshan Lin; Xiaoxiao Gou et al.

    Journal of Cardiovascular and Thoracic Research, Vol. 17 No. 2 · 2025 · English · DOAJ Scopus

    Introduction: Acknowledging lacking of recognition on postoperative aortic remodeling by intraoperative transition of cannulation perfusion mode during the open repair surgery of DeBakey type I acute aortic dissection (AAD), this study aims to investigate the effect of interactive cannulation…

  14. Journal Article Full text

    An integrated bioinformatics approach for identification of key modulators and biomarkers involved in atrial fibrillation

    Summan Thahiem; Ayesha Ishtiaq; Faisal Iftekhar et al.

    Journal of Cardiovascular and Thoracic Research, Vol. 17 No. 2 · 2025 · English · DOAJ Scopus

    Introduction: Atrial fibrillation (AFib) is a sustained form of cardiac arrythmia that occurs due to sympathetic overdrive, neurohumoral and electrophysiological changes. Sympatho-renal modulatory approach via miRNA-based therapeutics is likely to be an important treatment option for AFib. The…

  15. Journal Article Full text

    Fasting versus non-fasting before elective coronary angiography: A randomized clinical trial

    Fatemeh Baharvand; Arsalan Salari; Soheil Hasanipour et al.

    Journal of Cardiovascular and Thoracic Research, Vol. 17 No. 2 · 2025 · English · DOAJ Scopus

    Introduction: Coronary artery disease is a significant public health concern worldwide, with coronary angiography being a crucial diagnostic procedure. The safety and clinical outcomes of fasting versus non-fasting before elective coronary angiography have been a topic of debate. This study aimed…

  16. Journal Article Full text

    Is peres formula reliable for determination of proper position of central venous catheter tip in Iranian population?

    Maryam Ghanbari Garekani; Amirhossein Poopak; Hamidreza Pouraliakbar et al.

    Journal of Cardiovascular and Thoracic Research, Vol. 17 No. 2 · 2025 · English · DOAJ Scopus

    Introduction: Accurate positioning of central venous catheter (CVC) tips is essential to minimize complications such as arrhythmias, thrombosis, or cardiac tamponade. Methods: This study evaluated the reliability of the Peres formula, which estimates CVC tip placement based on patient height…

  17. Journal Article Full text

    Evaluation of neutrophil gelatinase-associated lipocalin (NGAL) levels as a biomarker for the early diagnosis of heart failure patients without of kidney disease

    Anahita Asadolahi Mashhadian; Hashem Nayeri; Ziba Rezvani Sichani

    Journal of Cardiovascular and Thoracic Research, Vol. 17 No. 2 · 2025 · English · DOAJ Scopus

    Introduction: Neutrophil Gelatinase-Associated Lipocalin (NGAL) is a specific early diagnostic biomarker for acute kidney injury and has shown high diagnostic value across various types of injuries with different etiologies. However, its role in heart failure (HF) diagnosis remains under…

  18. Journal Article Full text

    Fluctuations of epicardial adipose tissue and cardiovascular health: A useful biomarker? A comprehensive review

    Bekzod Isomitdinov; Muslim Mustaev; Malikabonu Khayatova et al.

    Journal of Cardiovascular and Thoracic Research, Vol. 17 No. 2 · 2025 · English · DOAJ Scopus

    Epicardial adipose tissue (EAT) is a fat layer of the heart located between the pericardium and myocardium and considered to be an important fat depot of the heart bearing thermoregulatory and protective functions, amongst others. Understanding of the dynamics of EAT, both positive and negative…