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Caspian Journal of Internal Medicine
Scopus
ISSN 2008-6164 · Babol University of Medical Sciences · 1.004 artikel di indeks
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Risk Factors of Caustic Agent Ingestion in a Single Centre in Tehran
Background: Caustic ingestion remains a preventable but persistent cause of morbidity in children. This study aimed to identify risk factors associated with caustic substance ingestion in children. Methods: In this case–control study, 122 children aged 30 million IRR) was associated with lower odds…
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Late isolated renal fossa recurrence of clear cell renal cell carcinoma 15 Years post-nephrectomy: A case report and literature review
Background: Clear cell renal cell carcinoma is the most common type of renal carcinoma and among them ccRCC is most common. We report a case of a patient diagnosed with renal cell carcinoma (RCC), who exhibited no metastases at the time of nephrectomy but experienced recurrence in the renal fossa…
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The relationship between visceral fat and diabetes mellitus in the elderly: a cross-sectional study
Background: Diabetes mellitus and obesity are major public health concerns in older adults, and visceral adipose tissue (VAT) is suggested to play a critical role in the metabolic dysfunction observed in type 2 diabetes. This cross-sectional study investigated the relationship between VAT and other…
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Levosimendan in Trastuzumab-Induced Cardiotoxicity: A Mechanism-Based Perspective
Trastuzumab is a cornerstone therapy in HER2-positive breast cancer, yet its association with cardiotoxicity remains a major limitation in clinical practice. Trastuzumab-induced cardiac dysfunction, although often considered non-necrotic and potentially reversible, frequently manifests as left…
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First case report of ectopic Cushing\'s syndrome secondary to synchronous mediastinal neuroendocrine tumors
Background: Ectopic Cushing's syndrome (ECS) is a rare cause of hypercortisolism resulting from non-pituitary adrenocorticotropic hormone (ACTH) secretion, most associated with neuroendocrine tumors (NETs) of pulmonary or gastrointestinal origin. Mediastinal NETs are an extremely rare source. Case…
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Hormonal Dysregulation in COVID-19: A Comparative Analysis of Cortisol, Growth Hormone, and IGF-1 Levels Across Different Severities of Illness
Background: COVID-19 has multiple effects on the endocrine system, particularly altering the levels of growth hormone (GH), insulin-like growth factor-1 (IGF-1), and cortisol, which may influence disease severity and prognosis. This study aimed to evaluate circulating levels of GH, IGF-1, and…
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Thalamic Atrophy in Active and Inactive Secondary Progressive Multiple Sclerosis Patients: A Comparative Study
Background: Thalamic atrophy may be an indicator of neurodegeneration in people with secondary progressive multiple sclerosis (pwSPMS). The atrophy usually begins asymmetrically, and the thalamic asymmetry index (TAI) can be used to estimate the severity of neurodegeneration. SPMS is commonly…
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Periodontal indices in patients with chronic obstructive pulmonary disease and their correlation with disease severity: A cross-sectional study
Background: Chronic obstructive pulmonary disease (COPD) is a chronic respiratory condition primarily influenced by oral microbiota, which is the source of the microbiome. This study evaluated selected periodontal indices in COPD patients and their relationship with COPD severity among patients…
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Exploring the Relationship Between Parathyroid Hormone, Pulmonary Artery Pressure, and Right Ventricular Function in Patients Undergoing or Awaiting Hemodialysis: Findings From a Cohort Study
Background: Cardiovascular disease is a leading cause of death in chronic kidney disease (CKD) patients, with pulmonary hypertension (PH) and right ventricular (RV) dysfunction being especially detrimental. Secondary hyperparathyroidism (SHPT), common in CKD-mineral and bone disorder (CKD-MBD), has…
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Antibiotic Susceptibility Pattern of ESBLs-producing Uropathogens in Kidney Transplant Recipients in North of Iran
Background: Due to the increasing global prevalence of extended-spectrum beta-lactamase (ESBL)-producing uropathogenic strains, ongoing surveillance is required to monitor drug-resistant organisms causing urinary tract infections (UTIs) in kidney transplant recipients (KTRs). This study aimed to…
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Depressive symptoms and related factors in adults with heart failure: A multicenter cross-sectional study in northern Iran (2022–2023)
Background: Depressive symptoms are frequent in patients with heart failure (HF), but estimates vary across settings. Clarifying their burden and related factors can inform integrated care. This study aimed to estimate the prevalence of depressive symptoms in adults with HF and identify associated…
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Association of Metabolic Syndrome and Its Components with Knee Osteoarthritis in the Older Adults of Amirkola City
Background: Knee osteoarthritis is a very common disease that leads to mobility disabilities in older adults. In recent years, a link between metabolic syndrome and knee osteoarthritis has been reported. However, there are conflicting findings regarding this association. Our study was conducted to…
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Innovative approaches: Utilizing artificial intelligence for early diagnosis of main neurodegenerative diseases
Background: By incorporating advanced signal processing and artificial intelligence (AI)/machine learning techniques (MLT) in an automated manner, this system can be trained using extensive patient data, physiological signals, and images. Using state-of-the-art AI models and high-quality clinical…
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Efficacy of Angiotensin Receptor Neprilysin Inhibitor (ARNI) in Right Ventricular Failure and preserved LV Ejection Fraction: A Systematic Review and Meta-Analysis
Background: Right ventricular (RV) failure with preserved left ventricular (LV) ejection fraction (LVEF ≥50%) is a distinct clinical entity often associated with pulmonary hypertension (PH), chronic lung diseases, or congenital heart defects, leading to significant morbidity and mortality…
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Associations of Intrinsic Capacity with COVID-19 Infection and Late Complications in the Older Adult Population
Background: Intrinsic capacity (IC) decline, infection susceptibility, and post-COVID sequelae in older adults, intensified by the pandemic, demand probing IC domains' infection/outcome links and population-level strategies for sustaining functional health. Methods: This cross-sectional study…
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Chronic systemic inflammation: A common pathway linking chronic diseases
Chronic systemic inflammation represents a unifying mechanism linking many of today's most prevalent chronic diseases. Although considerable progress has been made in elucidating its molecular pathways, important questions remain regarding optimal biomarkers, individualized risk assessment, and…
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Prevalence, Risk Factors, and Outcomes of Infective Endocarditis in People Living with HIV: A Systematic Review and Meta-Analysis of Intravenous Drug Use and Microbiological Profiles
Background: Infective endocarditis (IE) poses a significant challenge in PLWH, with risk factors and outcomes potentially differing from HIV-negative counterparts. This systematic review and meta-analysis aimed to assess the prevalence, risk factors, mortality, and clinical characteristics of IE in…
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When to wait and when to intervene: A retrospective study on predicting spontaneous clearance of common bile duct stones in ERCP candidates
Background: While ERCP is a cornerstone in the management of choledocholithiasis, a significant proportion of common bile duct (CBD) stones may clear spontaneously, prompting the need for better risk stratification. To identify independent clinical, biochemical, and radiologic predictors of…
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Global prevalence of recurrent aphthous stomatitis among school and university students: a systematic review and meta-analysis
Background: Aphthous lesions are common oral diseases that can affect the quality of life, especially in students, and are frequently triggered by factors such as stress. This study aimed to assess the global prevalence of recurrent aphthous stomatitis (RAS) among students. Methods: This systematic…
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Omicron Respiratory Threat in renal transplant recipients
Background: Omicron was identified as one of the worrisome strains of corona virus. Renal transplant recipients (RTRs) are classified as high-risk groups due to immunosuppressed conditions. Thus, this study was conducted with the aim of comparing these patients infected with the Omicron variant…
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