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MicrobiologyOpen
Scopus
ISSN 2045-8827 · Wiley · 1.151 artikel di indeks
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Artikel Jurnal
Semi‐Quantitative Detection of Respiratory Pathogens: A Systematic Review and Meta‐Analysis of Results From the BIOFIRE FILMARRAY Pneumonia Panel and Culture
ABSTRACT This systematic review and meta‐analysis compared bacterial semi‐quantification of respiratory samples from the BIOFIRE FILMARRAY Pneumonia (PN) Panels with quantitative and semi‐quantitative culture methods (qCMs). Fourteen studies comprising 1,654 samples were included. Across both…
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Artikel Jurnal
Alterations in Gut Microbiota and Metabolic Profiles in Relapsed or Refractory Lymphoma
ABSTRACT To identify potential therapeutic strategies for relapsed or refractory lymphoma (R/RL) by examining differences in gut microbiota composition and metabolic profiles between patients with R/RL and those with primary, treatment‐naïve lymphoma (PL), using fecal microbiota analysis and…
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Artikel Jurnal
Computational Validation of Multi‐Epitope mRNA Vaccine Targeting Streptococcus anginosus Surface Protein (TMPC) as an Effective Alternative Treatment to Reduce Gastric Cancer
ABSTRACT Streptococcus anginosus is a Gram‐positive coccus that can increase gastric cancer risk through interaction with the TMPC‐ANXA2‐MAPK axis in gastric epithelial cells. There is currently no commercially available vaccine, and prolonged antibiotic treatment may increase drug resistance. We…
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Artikel Jurnal
Antibiotic Resistance, Biofilm Genes, and smeDEF Efflux Pump in Clinical Stenotrophomonas maltophilia Isolates From Iran
ABSTRACT Stenotrophomonas maltophilia is a nosocomial and opportunistic microorganism with increasing antibiotic resistance rates. This study aimed to assess its biofilm production capacity, antibiotic resistance distribution, and the prevalence of biofilm‐ and resistance‐related genes in clinical…
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Artikel Jurnal
Reversing Antibiotic Resistance: Strategies From Adjuvants to Innovative Therapeutics
ABSTRACT The escalating prevalence of antibiotic resistance has become a major threat to the effectiveness of conventional antibiotics. Meanwhile, the development of novel antibiotics faces substantial challenges, including lengthy research cycles, high costs, and the rapid emergence of bacterial…
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Artikel Jurnal
Staphylococcus aureus Extracellular Vesicles Enhance PslE‐Mediated Pathogenesis in Pseudomonas aeruginosa
ABSTRACT Coinfection of Pseudomonas aeruginosa (P. aeruginosa) and Staphylococcus aureus (S. aureus) is frequently observed. Our previous study demonstrated that S. aureus‐derived extracellular vesicles (SaEVs) promote P. aeruginosa pathogenicity by increasing lipopolysaccharide (LPS) production…
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Artikel Jurnal
Hidden Partners in Diversity: Acidobacteriota and Their Distribution in the Cape Floristic Region
ABSTRACT The Cape Floristic Region, a biodiversity hotspot in South Africa, is characterised by acidic, nutrient‐poor soils and distinctive fynbos vegetation. Despite the ecological importance and metabolic versatility of Acidobacteriota, their diversity and functional roles in fynbos soils remain…
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Artikel Jurnal
Research Progress in the Treatment of Vaginitis With Bioactive Compounds: Targeting of Vaginal Microflora
ABSTRACT Vaginitis, a common gynecological ailment among women, poses a considerable health challenge with high recurrence rates even after conventional treatment. Vaginitis includes more common forms, such as bacterial vaginosis, vulvovaginal candidiasis, and Trichomonas vaginalis (TV), and less…
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Artikel Jurnal
Differentiating Damp‐Heat and Cold‐Damp Diarrhea in Rat Models via Gut Microbiota Dysbiosis and Short‐Chain Fatty Acid Profiling
ABSTRACT On the basis of gut microbiota and short‐chain fatty acids (SCFAs), this study aims to identify diagnostic biomarkers for damp‐heat diarrhea and cold‐damp diarrhea. Rat models of damp‐heat diarrhea and cold‐damp diarrhea were established. Changes in body weight, body temperature, food…
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Artikel Jurnal
BvrR From Brucella abortus Induces Neuroinflammation Through IRE1‐Mediated Activation of ATF2 and NF‐κB
ABSTRACT Brucella‐induced neuroinflammation represents a key mechanism in the development of neurobrucellosis. The objective of this investigation was to clarify the molecular pathways through which the BvrR contributes to neuroinflammation and cognitive dysfunction. Human microglial clone 3 (HMC3)…
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Artikel Jurnal
Bacterial Communities Associated With Crustose Coralline Algae Are Host‐Specific
ABSTRACT Crustose coralline algae (CCA) comprise hundreds of different species and are critical to coral reef growth, structural stability and coral recruitment. Despite their integral role in reef functioning, little is known about the diversity and structure of bacterial communities associated…
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Artikel Jurnal
Antibody–Antibiotic Conjugates: Mechanisms, Clinical Progress, and Next‐Generation Strategies Against Multidrug‐Resistant Bacterial Infections
ABSTRACT The rise of multidrug‐resistant (MDR) bacterial pathogens presents a critical challenge to global health, highlighting the need for innovative therapeutic strategies beyond conventional antibiotics. Antibody–antibiotic conjugates (AACs) combine the high specificity of monoclonal antibodies…
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Artikel Jurnal
The Burden of Antimicrobial‐Resistant Pseudomonas aeruginosa Isolates in Children With Cystic Fibrosis: Molecular Characterization and Genotyping Analysis
ABSTRACT Pseudomonas aeruginosa poses a significant therapeutic challenge in pediatric patients with cystic fibrosis (CF) due to increasing multidrug resistance (MDR) and carbapenem resistance, underscoring the need for surveillance to guide treatment strategies. In this study, sputum and throat…
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Artikel Jurnal
Rapid Typing of Extended‐Spectrum β‐Lactamase (ESBL)‐ and Metallo‐β‐Lactamase (MBL)‐Producing Enterobacterales Using Fourier Transform Infrared (FT‐IR) Spectroscopy
ABSTRACT This study investigated the usefulness of the IR Biotyper, which types bacterial strains using Fourier transform infrared (FT‐IR) spectroscopy, against extended‐spectrum β‐lactamase (ESBL)‐ and metallo‐β‐lactamase (MBL)‐producing Enterobacterales. Sixty‐six clinical isolates (20…
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Artikel Jurnal
Diagnostic Performance of the QIAstat‐Dx Meningitis/Encephalitis Panel: Insights From Seven Clinical Evaluations
ABSTRACT Central nervous system (CNS) infections require prompt and accurate diagnosis to enable timely and targeted antimicrobial therapy. Syndromic PCR‐based assays, such as the QIAstat‐Dx Meningitis/Encephalitis Panel (QIA‐ME), allow rapid detection of key pathogens directly from cerebrospinal…
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Artikel Jurnal
An Eco‐Friendly Synthesis and Characterization of Antibacterial, Antifungal, and Antioxidant Silver Nanoparticles From Bioactive Streptomyces sp. Strain WSN‐2
ABSTRACT The present study reports the isolation and molecular identification of Streptomyces sp. strain WSN‐2 using 16S rRNA gene sequencing and BLASTn analysis (GenBank Accession No. MN128377), followed by its application in the green synthesis of silver nanoparticles (AgNPs). Biomass filtrate of…
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Artikel Jurnal
Efficacy, Safety and Biological Characteristics of Formulation Based on Essential Oil Against Co‐Infections of Herpes Simplex Virus‐1 and Candida albicans
ABSTRACT Oral coinfections involving herpes simplex virus (HSV) and Candida albicans can potentially interact and exacerbate each other. Starting from bibliographical investigation, this study aimed to examine the effectiveness of some essential oils (EOs), and their commercial formulations, both…
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Artikel Jurnal
Harnessing the Gut Microbes of Low Abundance With a Bent‐Capillary‐Centrifugal‐Driven (BCCD) Microdroplet Method
ABSTRACT Gut microbe cultivation is essential for studying host‐microbiota interactions. Traditional cultivation methods often fail to recover microbial species at low abundance (
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Artikel Jurnal
Diverse Forage Enhances the Antimicrobial Potency of Australian Honey
ABSTRACT Antimicrobial resistance is a critical global health crisis, driving renewed interest in natural alternatives like honey. Australia's diverse native flora offers unique opportunities for producing bioactive honeys, yet their antimicrobial potential remains underexplored. This study aimed…
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Artikel Jurnal
Patulin Biodegradation by Rhodosporidiobolus ruineniae and Meyerozyma guilliermondii Isolated From Fruits
ABSTRACT Patulin (PAT) is a toxic secondary metabolite produced by certain species of Penicillium and Aspergillus on pome fruits. In this study, we isolated Rhodosporidiobolus ruineniae (R. ruineniae) and Meyerozyma guilliermondii (M. guilliermondii) from a peach and an apple as candidates for PAT…
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