1.444 hasil
Menampilkan 1–20 · 0,07 detik · RSS
Pulmonary Circulation
Scopus
ISSN 2045-8940 · Wiley · 1.444 artikel di indeks
-
Artikel Jurnal
Splenic Focused Ultrasound Improves Experimental Pulmonary Hypertension and Reprograms Immune Responses in Female and Male Rats
ABSTRACT Splenic focused ultrasound (sFUS) neuromodulation improves monocrotaline‐induced pulmonary hypertension in rats of both sexes, with females achieving near‐normalization of right ventricular systolic pressure and males showing partial improvement. In male and female animals, sFUS reduces…
-
Artikel Jurnal
Transitions From Parenteral Prostacyclin Analogues to Selexipag in Patients With Pulmonary Arterial Hypertension
ABSTRACT Pulmonary arterial hypertension (PAH) is a progressive illness that may require therapy with parenteral prostacyclin pathway agents (PPA) (epoprostenol and treprostinil). These parenteral PPA's are continuous ambulatory infusions that require a high level of skill and knowledge to maintain…
-
Artikel Jurnal
The Heterogeneity of Long‐Term Cardiopulmonary Outcomes in Children Born Preterm May Benefit from Pulmonary Hypertension‐Specialty Outpatient Follow‐Up
ABSTRACT Preterm birth survivors reaching adulthood are a growing population, with bronchopulmonary dysplasia (BPD), the chronic lung disease of prematurity, common among this cohort. Infants with BPD are at increased risk for pulmonary vascular disease (PVD) including the development of pulmonary…
-
Artikel Jurnal
Pathogenesis and Phenotypes of Pulmonary Vascular Disease in COPD: A Consensus Statement From the Pulmonary Vascular Research Institute's Innovative Drug Development Initiative – PH Group 3 Workstream
ABSTRACT Chronic obstructive pulmonary disease (COPD) is frequently associated with pulmonary vascular disease (PVD) yet pulmonary vascular involvement remains underrecognized and incompletely phenotyped. Emerging evidence demonstrates that pulmonary vasculopathy may precede overt emphysema and…
-
Artikel Jurnal
Lung Injury After Balloon Pulmonary Angioplasty for CTEPH: Histopathologic Findings and Management Implications
ABSTRACT Balloon pulmonary angioplasty (BPA) has emerged as a guideline‐recommended therapy for surgically inoperable chronic thromboembolic pulmonary hypertension (CTEPH). Lung injury occurs in approximately 6% of BPA sessions and is the leading cause of procedure‐related mortality. While lung…
-
Artikel Jurnal
Validation of Tricuspid Annular Displacement by Tissue Doppler in Pulmonary Hypertension
ABSTRACT Tricuspid annular plane systolic excursion (TAPSE) is primarily measured using motion‐mode (M‐mode) echocardiography. However, image resolution doesn't always provide clear visualization. In these cases, tissue Doppler imaging (TDI) may offer a valuable alternative for right ventricular…
-
Artikel Jurnal
Right Ventricular to Left Ventricular (RV/LV) Blood Pool T2 Ratio Is Associated With Invasive Hemodynamics Across Pulmonary Hypertension Subgroups
ABSTRACT Pulmonary hypertension (PH) is defined by elevated mean pulmonary arterial pressure (mPAP). Pulmonary vascular resistance (PVR) and SvO2 (mixed venous oxygenation), measured by right heart catheterization (RHC), are key determinants of disease severity and prognosis. The right‐to‐left…
-
Artikel Jurnal
Invasive Management for Acute‐on‐Chronic Thromboembolic Pulmonary Hypertension: Feasibility and Clinical Outcomes in a Single‐Center Cohort
ABSTRACT Acute‐on‐chronic thromboembolic pulmonary hypertension (acute‐on‐CTEPH) is associated with rapid clinical deterioration, yet the role of invasive intervention in the acute phase remains poorly defined. We retrospectively analyzed consecutive patients with acute‐on‐CTEPH presenting with…
-
Artikel Jurnal
Global Burden of Pulmonary Arterial Hypertension in Older Adults and Its Causal Association With Body Mass Index
ABSTRACT Pulmonary arterial hypertension (PAH) is a severe cardiopulmonary disease associated with substantial morbidity and mortality. However, the global burden, future trajectory, and potentially modifiable risk factors for PAH among older adults remain insufficiently characterized. This study…
-
Artikel Jurnal
Phenotypic Clustering of Idiopathic Pulmonary Arterial Hypertension: Insights Into Pulmonary Vascular and Cardiometabolic Co‐Morbidity Trajectories
ABSTRACT Idiopathic pulmonary arterial hypertension (IPAH) exhibits significant clinical heterogeneity, necessitating a precision medicine approach. This study aimed to identify distinct IPAH phenotypes using machine learning‐based clustering and to evaluate their longitudinal therapeutic responses…
-
Artikel Jurnal
Effect of Incident Pulmonary Arterial Hypertension on Risk of Newly‐Diagnosed Mental Health Conditions
ABSTRACT Pulmonary arterial hypertension (PAH) is a life‐limiting disease with psychosocial burden, although US population‐level estimates of incident mental health (MH) disorders remain limited. In this retrospective cohort study using Komodo Research Data (01/01/2016−03/31/2024), we evaluated the…
-
Artikel Jurnal
Long‐Term Supervised Cardiac Rehabilitation After Balloon Pulmonary Angioplasty Improved Residual Exercise Pulmonary Hypertension in Patients With Chronic Thromboembolic Pulmonary Hypertension: A Two‐Case Report
ABSTRACT Abnormal pulmonary hemodynamics during exercise may persist even after balloon pulmonary angioplasty (BPA) for inoperable chronic thromboembolic pulmonary hypertension (CTEPH). We report two female patients who underwent long‐term supervised outpatient cardiac rehabilitation (CR) after BPA…
-
Artikel Jurnal
Long‐Term Subcutaneous Treprostinil in Pediatric Pulmonary Arterial Hypertension at a Latin American Referral Center: A Retrospective Cohort Study
ABSTRACT Pediatric pulmonary arterial hypertension is a progressive vasculopathy with substantial early mortality. Subcutaneous treprostinil is an established prostacyclin‐pathway therapy for higher‐risk disease, but long‐term pediatric data from Latin American referral centers remain limited. This…
-
Artikel Jurnal
Pulmonary Arterial Hypertension in Octogenarians: The Pulmonary Hypertension Association Registry
ABSTRACT Pulmonary arterial hypertension (PAH) was historically viewed as a disease of young adults; however, emerging evidence suggests rising prevalence in the elderly, which is an insufficiently characterized population. We evaluated clinical and sociodemographic features of PAH patients over 80…
-
Artikel Jurnal
Association Between Serum Uric Acid and Pulmonary Hypertension in Takayasu Arteritis With Pulmonary Artery Involvement: A Cross‐Sectional Study
ABSTRACT Pulmonary hypertension (PH) is a severe complication of Takayasu arteritis (TAK) with pulmonary artery involvement (PAI), associated with poor prognosis. Serum uric acid (UA) has been linked to both TAK severity and PH in other settings, but its role specifically in TAK‐PAI‐associated PH…
-
Artikel Jurnal
Referral Patterns and Clinical Characteristics of Patients With Pulmonary Hypertension at a Comprehensive Care Center
ABSTRACT Pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) are life‐threatening forms of pulmonary hypertension (PH) that require early recognition and referral to expert centers. In 2014, the Pulmonary Hypertension Association (PHA) launched the…
-
Artikel Jurnal
Quality of Pulmonary Hypertension Care Within Expert PH Centers: Patient and Provider Perspectives From a Multi‐Site Qualitative Study
ABSTRACT Pulmonary hypertension (PH) is a progressive disease associated with high morbidity and mortality. Despite advancements, gaps in PH care quality persist, though the drivers of these gaps are incompletely understood. Thus, we sought to explore patient and provider perspectives on…
-
Artikel Jurnal
The Causal Role of Gut Microbiota in Pulmonary Embolism and the Mediating Effects of Circulating Metabolites: A Mendelian Randomization Study
ABSTRACT The gut microbiota has been implicated in pulmonary vascular diseases, yet a direct causal link to pulmonary embolism (PE) remains unestablished. This study aimed to investigate the causal effects of gut microbiota on PE and to explore the mediating role of circulating metabolites in this…
-
Artikel Jurnal
Noninvasive Gas Exchange Determinants of Exercise Hemodynamics in Non‐Severe Pulmonary Hypertension Associated With Interstitial Lung Disease
ABSTRACT Level 3 cardiopulmonary exercise testing (CPET) can unmask the dynamic burden of pulmonary vascular disease (PVD), while submaximal exercise testing offers a simpler, noninvasive alternative. Emerging markers such as a gas‐exchange derived estimate of pulmonary vascular capacitance (GXCAP)…
-
Artikel Jurnal
Pulmonary Function and Exercise‐Based Assessments for the Detection of Pulmonary Hypertension in Fibrotic Interstitial Lung Disease
ABSTRACT Pulmonary hypertension (PH) is a frequent complication of fibrotic interstitial lung diseases (ILDs), but its detection remains challenging due to overlapping clinical features. We aimed to evaluate the discriminatory power of physiological and exercise‐based markers that differentiate…
Menampilkan maksimal 50 halaman. Persempit pencarian dengan filter untuk hasil yang lebih spesifik.