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European Journal of Medical Research
Dikeluarkan Scopus 2024
ISSN 2047-783X · BMC · 4.907 artikel di indeks
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Artikel Jurnal
Prediction of cardiovascular mortality based on iron metabolism in patients with cardiovascular–kidney–metabolic syndrome: development and validation of clinical predictive model
Abstract Background Iron metabolism is associated with cardiovascular disease (CVD) mortality in patients with cardiovascular–kidney–metabolic (CKM) syndrome. However, its prognostic significance remains unclear. This study was aimed at evaluating incorporation of iron metabolism indicators as a…
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Artikel Jurnal
Prospective association between the triglyceride-glucose index and frailty in middle-aged and older adults: insights from a nationwide cohort study
Abstract Background Frailty is notably prevalent in individuals aged 50 and older and has been associated with metabolic dysfunction. The triglyceride-glucose (TyG) index is a reliable surrogate marker for insulin resistance. This study aimed to investigate the association between the TyG index and…
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Artikel Jurnal
Sevoflurane-induced hemispheric cerebral blood flow reduction in mice with revived global perfusion after carotid artery occlusion
Abstract Background Carotid artery disease (CAD) presents a significant risk for ischemic stroke. Understanding the pathophysiological changes following carotid artery occlusion, particularly regarding cerebral blood flow (CBF) and cerebrovascular reactivity (CVR), is essential for developing…
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Artikel Jurnal
Effects of atorvastatin on inflammatory markers, lipid profile, liver enzymes, and pulmonary function in patients with lung diseases: a systematic review and meta-analysis of randomized controlled trials
Abstract Background Pulmonary diseases are important causes of morbidity globally. Atorvastatin's pleiotropic effects, which include anti-inflammatory and lipid-lowering properties, may be beneficial for individuals with respiratory diseases. This meta-analysis evaluated the atorvastatin's effect…
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Artikel Jurnal
Activated notch signaling pathway protects the intestinal barrier in DSS-induced colitis by regulating tight junctions
Abstract Background and aims Studies have suggested that the activation of Notch pathway may provide protection to the intestinal mucosal barrier. However, the underlying mechanism remains to be elucidated. Methods In vivo experiments, the dextran sulfate sodium (DSS)-induced colitis mice were used…
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Artikel Jurnal
Correlation between ambulatory blood pressure indices and sex hormone imbalance in hypertensive women with different menopausal durations: a cross-sectional study
Abstract Background The prevalence of hypertension in postmenopausal women increases significantly compared to premenopausal women and gradually catches up with, or even exceeds, that of their male counterparts. Imbalanced levels of sex hormones play a critical role in the elevation of blood…
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Artikel Jurnal
Serum butyraldehyde levels are associated with abdominal aortic calcification: a population-based study
Abstract Background Abdominal aortic calcification (AAC) is a strong predictor of cardiovascular morbidity but lacks effective interventions. Aldehydes, a diverse class of environmental and endogenous compounds, have been implicated in various chronic diseases, yet their individual and combined…
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Artikel Jurnal
PEAK1 promotes prostate cancer progression and docetaxel resistance by mediating the polarization of tumor-associated macrophages
Abstract Background Pseudopodium-enriched atypical kinase 1 (PEAK1) expression is altered in multiple human malignancies and promotes tumor proliferation, metastasis, and chemical therapy resistance. Here, we aimed to investigate the role and mechanisms of PEAKs in prostate cancer (PCa) progression…
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Artikel Jurnal
Machine learning model integrating radiomics and clinical features for predicting postoperative bleeding after percutaneous nephrolithotomy
Abstract Background and objective Radiomics and machine learning play significant roles in clinical medical research, particularly in developing prediction models. This study aims to combine radiomic features with clinical variables and apply machine learning to predict the risk of postoperative…
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Artikel Jurnal
Dietary inflammatory index (DII) and attention deficit hyperactivity disorder: a cross-sectional study in US children and adolescents and Mendelian randomization study
Abstract Background Diet may impact the risk of attention deficit hyperactivity disorder (ADHD) via altering inflammation. However, no investigations have been conducted to evaluate the relationship between ADHD and the diet's inflammatory potential. The study sought to investigate the relationship…
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Artikel Jurnal
Predicting postoperative liver metastasis in colorectal cancer through CT radiomics model based on liver, spleen, and tumor
Abstract Purpose The burden of postoperative liver metastasis (LM) in colorectal cancer remains substantial. Consequently, there is a pressing demand for highly effective predictive biomarkers to expedite early diagnosis and treatment. Materials and methods Using a retrospective design, 273…
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Artikel Jurnal
A novel nomogram based on inflammatory indexes for predicting short-term prognosis in acute-on-chronic liver failure: a comparison with classical models
Abstract Background This study aimed to develop and validate a novel nomogram that incorporates the neutrophil percentage-to-albumin ratio (NPAR) for predicting 30-day and 90-day unfavorable outcomes in acute-on-chronic liver failure (ACLF) patients. Methods We retrospectively enrolled 641 ACLF…
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Artikel Jurnal
Multi-strain synbiotic and lifestyle modifications on patients with metabolic dysfunction-associated steatotic liver disease (MASLD): a randomized double-blinded placebo-controlled trial
Abstract Background MASLD is the most common chronic liver disease and the leading cause of liver-related morbidity and mortality globally. While probiotic supplementations show promise as adjunctive therapy, existing trials are limited by the quality of evidence, small sample sizes, and…
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Artikel Jurnal
Impact of mineral oil overlay on immature oocyte maturation in an optimized in vitro culture system
Abstract Background To assess the impact of oil overlay during maturation of immature oocytes in vitro in our optimized liquid culture system. Methods We conducted comparative analyses of pH, osmolality, and the levels of melatonin, FSH, E2, and hCG in the culture medium between oil-covered group…
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Artikel Jurnal
Non–HDL to HDL cholesterol ratio and coronary outcomes in U.S. adults: a cross-sectional and prospective NHANES analysis
Abstract Background Coronary heart disease (CHD) remains a leading global cause of morbidity and mortality. Dyslipidemia—particularly elevated non-high-density lipoprotein cholesterol (non–HDL-C) and reduced high-density lipoprotein cholesterol (HDL-C)—is a key risk factor for CHD. The ratio of…
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Artikel Jurnal
Veillonella, Neisseria, Prevotella, and Lachnoanaerobaculum enrichment in salivary microbiome predicts gallstone disease
Abstract Introduction Gallstone disease (GSD) is a common hepatobiliary disorder influenced by bile composition, biliary drainage, and gallbladder motility. Emerging evidence suggests that oral microbiota may contribute to GSD development, but its role remains unclear. This study explores salivary…
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Artikel Jurnal
GATA4-overexpressing BMSCs-derived exosome regulation of myocardial infarction in mice by key miRNA and apoptosis gene CLU
Abstract Background Myocardial infarction (MI) is the most common cardiovascular disease that has a serious impact on human health and is one of the most common causes of death in the world. Apoptosis and myocardial fibrosis after MI are the key pathological features of poor myocardial remodelling…
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Artikel Jurnal
Dietary intake of B vitamins and cancer risk in women: a mixture analysis approach of NHANES 2007–2020
Abstract Background Although B vitamins are often consumed through multivitamin containing foods, their potential synergistic effects on cancer risk remain insufficiently elucidated. Objective We aimed to study the relationship between mixed intake of B vitamins, cancer, and overall and…
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Artikel Jurnal
Development and validation of a risk prediction model for urinary retention after pelvic floor reconstruction: a retrospective cohort study
Abstract Objectives To investigate and analyze the factors affecting postoperative urinary retention (POUR) after pelvic floor reconstruction, and to construct and validate a risk prediction model. Methods This retrospective cohort study included 258 pelvic floor reconstruction patients (2023–2024)…
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