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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Scopus
ISSN 2047-9980 · Wiley · 11.381 artikel di indeks
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Artikel Jurnal
Principal Component‐Based Comprehensive Physical Health Score Associates With Long‐Term Death in Patients With Ischemic Stroke
Background Principal component analysis (PCA) integrates multiple clinical indicators into a single score, providing a holistic assessment. Existing clinical indicators often fail to fully reflect health conditions. To address this gap, our study constructs a comprehensive physical health score…
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Artikel Jurnal
Left Atrial Volume Index and Left Ventricular Mass Index Determine the Benefits of Spironolactone in Patients With Heart Failure With Preserved Ejection Fraction
Background It is unclear whether patients with heart failure with preserved ejection fraction respond to spironolactone based on cardiac structure or function. Methods A post hoc analysis was performed among participants with left ventricular (LV) ejection fraction ≥50% and evidence of abnormal LV…
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Simple Index for Identifying Patients at Increased Risk of Suboptimal Forward‐Flow Hemodynamics After Transcatheter Aortic Valve Replacement
Background Among patients treated for severe aortic stenosis, a small aortic annulus could have a different impact on outcomes according to body size. We aimed to compare forward‐flow hemodynamics and clinical outcomes after transcatheter aortic valve replacement in patients with small annuli…
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Artikel Jurnal
Ex Vivo Hypothermic Perfusion Enables 48‐Hour Heart Preservation and Bench‐Top Functional Recovery via Normothermic Reperfusion in a Porcine Model
Background Ex vivo oxygenated perfusion systems are a promising approach to extend cardiac allograft preservation beyond the typical 4 to 6 hours limit allowed by static cold storage (SCS). Hypothermic oxygenated perfusion (HOPE) has been proven to safely preserve donor hearts, yet its underlying…
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Ex Vivo Effect of Apixaban on Hemostatic Biomarkers in Children With Heart Disease: A SAXOPHONE Trial Substudy
Background The SAXOPHONE (Safety of Apixaban on Pediatric Heart Disease on the Prevention of Embolism) trial demonstrated the safety of apixaban for thromboprophylaxis in children with heart disease. Included a priori in the trial design was an exploratory biomarker substudy to evaluate the effects…
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Artikel Jurnal
Predicting Recurrence and Outcomes After Stressor‐Associated Atrial Fibrillation Using ECG‐Based Deep Learning
Background Stressor‐associated atrial fibrillation (AF) refers to new‐onset AF that occurs with a reversible, acute stressor. Identifying individuals at highest risk for AF recurrence is essential to guide management. Although clinical factors have shown limited value, the utility of contemporary…
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Artikel Jurnal
Sex‐Based Differences in Outcomes Following Mitral Valve Surgery: A Contemporary Analysis From 2 Institutions
Background Despite differences in operative characteristics in patients with mitral valve disease, it remains unclear if sex is an independent risk factor associated with perioperative mortality after mitral valve surgery. Methods We performed a retrospective cohort study of 3313 adult patients who…
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Artikel Jurnal
Clinical, Functional, and Quality‐of‐Life Outcomes After Contemporary Transcatheter Edge‐to‐Edge Repair for Primary Mitral Regurgitation in the Very Elderly
Background Advanced age may influence the benefits derived from transcatheter edge‐to‐edge repair for primary mitral regurgitation (MR). We explored the impact of age on clinical, echocardiographic, functional, and patient‐reported outcomes after contemporary mitral transcatheter edge‐to‐edge…
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Incidence and Outcomes of Intraluminal Frozen Elephant Trunk Stent Graft Thrombosis After Aortic Arch Surgery: Systematic Review and Meta‐Analysis
Background Intraluminal thrombosis (ILT) has been observed in endografts in the thoracic aorta after frozen elephant trunk (FET) for aortic arch pathologies. This study aimed to evaluate the incidence and clinical outcomes associated with ILT. Methods Systematic review of studies reporting…
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Artikel Jurnal
Number of Live Births as a Protective Factor Against Clinical and Covert Brain Infarcts: The Framingham Heart Study
Background Female‐specific reproductive factors have been associated with stroke risk, although evidence for some factors (eg, live births) remains conflicting. We determined the association between number of live births and other female‐specific reproductive factors and subsequent risk of stroke…
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Trends in Polypharmacy Among Patients With Atrial Fibrillation: A Report From the Finnish AntiCoagulation in Atrial Fibrillation Nationwide Cohort Study
Background Polypharmacy, commonly defined as the concurrent use of ≥5 medications, is associated with adverse outcomes, but comprehensive data on its prevalence and temporal trends in patients with atrial fibrillation (AF) are limited. Methods We conducted a nationwide retrospective cohort study…
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Sex Differences in Outcomes After Breakthrough Ischemic Stroke on Oral Anticoagulants for Atrial Fibrillation: An ASPERA‐R Inverse Probability Weighted Analysis
Background Sex‐specific outcomes after breakthrough ischemic stroke on oral anticoagulation (OAC) are unexplored. We compared 90‐day outcomes by sex and explored modifiers. Methods ASPERA‐R (Advancing Knowledge in Ischemic Stroke Patients on Oral Anticoagulants retrospective cohort; NCT06823466)…
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Artikel Jurnal
Association of Multiple Plasma Metals With Cerebral Microbleeds: A Brain Magnetic Resonance Imaging‐Based Study
Background Exposure to metals in the external environment and system circulation has been linked to cerebrovascular health. However, population‐based epidemiological evidence on the association between multiple metals and cerebral microbleeds (CMBs) is lacking. Methods We conducted a…
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Artikel Jurnal
Air Pollution and Incident Cardiovascular Disease: Modification by Genetic Susceptibility and the Mitigating Role of Physical Activity
Background The interplay and joint effects of air pollution, genetic predisposition, and physical activity (PA) on incident cardiovascular disease (CVD) remain poorly understood. This study aimed to examine the associations between various air pollutants and CVD and assessed potential modification…
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Major Adverse Events of Cardiac Catheterization in Pediatric Cardiomyopathy: Insights From the IMPACT Registry
Background Despite the role of cardiac catheterization for hemodynamic assessment and endomyocardial biopsy in children with cardiomyopathy, data on procedure‐related major adverse events (MAE) in this population are lacking. We aim to describe the rate of MAE in children with cardiomyopathy…
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Association Between Copayments and Attendance in Cardiac Rehabilitation: A Nationwide Analysis From the AACVPR Registry
Background Improving cardiac rehabilitation (CR) participation is a national priority. This study examines the prevalence and cost of copays and their relationship with CR attendance and dropout. Methods We analyzed the AACVPR (American Association of Cardiovascular and Pulmonary Rehabilitation)…
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Artikel Jurnal
Insights Into the Natural History of Recurrent Myocarditis, A Multicenter International Study (Re‐Myo Study)
Background Recurrence of acute myocarditis (AM) is challenging. The management and natural history of patients who experience a recurrence of AM (Re‐AM) remain poorly characterized. The aim of this study is to investigate clinical characteristics and outcomes of patients with Re‐AM. Methods In this…
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Artikel Jurnal
Low‐Density Lipoprotein Cholesterol Lowering With Inclisiran Plus Usual Care in Recent Acute Coronary Syndrome: VICTORION‐INCEPTION, a Randomized, Controlled, Open‐Label Trial
Background The low‐density lipoprotein cholesterol (LDL‐C)‐lowering effect of inclisiran, a proprotein convertase subtilisin/kexin type 9‐targeting small interfering RNA, has not been established in patients with recent acute coronary syndrome. Methods VICTORION‐INCEPTION, a 330‐day, phase 3b…
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