400 hasil
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JRSM Open
ISSN 2054-2704 · SAGE Publishing · 400 artikel di indeks
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Artikel Jurnal
Retrospective diagnosis: process, outputs and relevance
In this review, it is suggested that the process of generating robust and reliable retrospective diagnoses for historical figures should focus on four issues: the historical and medical contexts; language and understanding; diseases and disease concepts; evidence acquisition and appraisal. In terms…
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Artikel Jurnal
The effects of menopausal hormone therapy on cardiovascular disease, cancer, cognition and depression in younger women: A systematic review
Objective The Women's Health Initiative (WHI), a randomized controlled trial, found no overall health benefit of menopausal hormone therapy. Our objective was to evaluate the hypothesis that initiating hormonal therapy prior to age 60 or within a few years after the last menstrual period provides…
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A National Health Service in ‘Serious Trouble’: What do multiple long-term conditions tell us about deterioration in health among people accessing hospital care in the North East of England? – An analysis of electronic health records
Summary Objectives To estimate the prevalence of multiple long-term conditions (MLTC) among people accessing hospital care in North East England, and to assess associations with age, sex, ethnicity and neighbourhood deprivation. Design Analysis of electronic health records. Setting Secondary care…
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Anti-racism in postgraduate medical curricula: A review of curricula
Summary Objectives To assess how UK postgraduate medical organisations have responded to calls for action on structural racism, and to examine the extent to which anti-racism is embedded in postgraduate medical curricula and learning outcomes. Design We conducted a review of publicly available…
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Artikel Jurnal
Symptom burden in multiple long-term conditions: An AI-supported, mixed-methods concept elicitation study
Summary Objective To develop the conceptual framework for an MLTC-specific patient-reported outcome measure (PROM), the Symptom Burden Questionnaire™ for MLTC (SBQ™-MLTC). Design Mixed-methods study: (1) symptom list generation; (2) assessment of list face validity; and (3) construction of a…
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Artikel Jurnal
New drug applications to Health Canada cancelled and refused: Cross-sectional study
Objectives This study looks at the number of cancellations by companies and refusals by Health Canada of new drug applications from 1 June 2019 to 1 July 2025 and the amount of information given for the decisions taken. Design Cross-sectional. Setting Canada. Participants New drug applications…
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Perioperative hormone replacement therapy (HRT) and venous thromboembolism risk: a scoping review of available evidence and guidance
Summary Objective Hormone replacement therapy (HRT) is used to manage menopausal symptoms, but its perioperative use raises concerns about increased venous thromboembolism (VTE) risk. Clinical guidelines vary, with some advising temporary discontinuation before surgery. This scoping review aims to…
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Effect of COVID-19 NHS breast screening pause on breast cancer presentation and management: an insight into overdiagnosis
Objective: To ascertain the impact of a 3-month pause in the NHS Breast Screening Programme (NHSBSP) during COVID-19 on numbers, characteristics and outcomes of breast cancer patients Design: We compared numbers, referral sources (NHSBSP/GP), tumour characteristics, treatments, and survival before…
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The Rashōmon Effect and COVID-19 vaccine decision-making: A qualitative study
Objectives This qualitative study captured the perspectives of patients and healthcare professionals to better understand COVID-19 vaccine decision-making among South Asians in London. Design In-depth semi-structured telephone and virtual interviews were conducted using convenience and purposive…
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How should services for high-intensity users be organised? A scoping review of published literature with recommendations for future research and delivery of care
Abstract Objective High Intensity Users (HIUs) of Urgent and Emergency Care (UEC) services account for disproportionately high numbers of Emergency Department (ED) attendances, ambulance journeys and non-elective admissions. This review aimed to assess the quality and completeness of evidence for…
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Artikel Jurnal
Mapping the evidence on the role and impact of plastics in the context of health products and their packaging: A scoping review
Abstract Objective: To map the global research on the impact of plastic-based health products and their packaging across the product lifecycle in order to inform equitable, sustainable governance for the role of plastics in health products. Design: A scoping review of primary research and…
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Structured medication reviews for patients with polypharmacy in primary care: a cross-sectional study in North West London, UK
Summary Objectives To identify the number and characteristics of patients with polypharmacy receiving structured medication reviews (SMRs) and medication reviews in primary care in 2022, and to evaluate whether the provision of these services is equitable across different demographic and…
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Artikel Jurnal
De novo thyroid eye disease following COVID vaccination several years after radioiodine therapy
Lesson The delayed onset of thyroid eye disease is well recognised but less commonly perceived in routine clinical practice and this case report serves as a reminder for a high index of suspicion in at-risk patients.
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Artikel Jurnal
The UK's Early Access to Medicines Scheme 10 years on: an evaluation using publicly available data
Objectives To investigate the drugs and indications that have passed through the UK's Early Access to Medicines Scheme (EAMS) to date, the type of evidence the regulator considers when accepting a drug into the EAMS, and potential risks to patients. Design Analysis of publicly available data: MHRA…
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Therapeutic value of oncology products with a conditional approval from Health Canada: a cross-sectional study
Summary Objectives Investigate the additional therapeutic value compared to existing medicines of new oncology drugs given a conditional approval (Notice of Compliance with conditions, NOC/c) by Health Canada using therapeutic ratings from four independent organisations. Design A list of all new…
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The importance of multiculturalism in medical education: a global comparison of perspectives from medical and health professions students at 21 universities
Objectives This study aims to quantitatively assess the baseline level of self-perceived cultural competency preparedness and skillfulness among medical and health professions students from 21 universities around the world utilizing a previously validated and standardized testing tool. Design…
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Ease of access to general practice, patient experience and use of the NHS App: an ecological analysis of English data
Summary Objective To assess the relationship between GP experience, phone and website access measures, and NHS App use. Design An ecological study using practice-level NHS App usage data between March 2020 and June 2022. GP practice codes were used to link patient-reported experience and ease of…
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Ecological footprint of salbutamol administration by metered-dose inhaler versus nebulisation in acute asthma: a life-cycle assessment
Objective The scientific evidence indicates little or no difference in the effectiveness or cost of using of metered-dose inhalers (MDIs) versus nebulisation to treat acute asthma in the emergency department (ED). However, the use of MDIs raises questions of environmental impact. Our objective was…
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The association of ethnicity and migration status with agenda for change pay band in National Health Service healthcare workers: Results from the United Kingdom Research study into Ethnicity and Coronavirus Disease 2019 (COVID-19) Outcomes in Healthcare workers (UK-REACH)
Summary Objectives Ethnic minority and migrant healthcare workers (HCWs) constitute 24% of the UK's National Health Service. Migration status, often overlooked in Human Resources records, is associated with their placement within the Agenda for Change (AfC) pay bands. Therefore, we analysed the…