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Canadian Journal of Kidney Health and Disease
Scopus
ISSN 2054-3581 · SAGE Publishing · 956 articles in the index
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Journal Article
Using an Electronic Medical Record to Evaluate Pediatric Blood Pressure Follow-Up: Limitations of Automated Data Extraction in a Nephrology Cohort
Background Hypertension is a prevalent condition in the pediatric population. Diagnosis and management can be challenging. The widespread adoption of electronic medical records (EMRs) has revealed their potential for improving patient care and research. Objectives This study used EMR data from the…
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Journal Article
Challenges in Predicting Estimated Glomerular Filtration Rate Slope Among Adult Patients With IgA Nephropathy: A Population-Based Cohort Study
Background Traditional epidemiologic studies and clinical trials in IgA nephropathy (IgAN) have focused on kidney failure or large declines in estimated glomerular filtration rate (eGFR) as primary outcomes. Two-year eGFR slope has emerged as a validated surrogate endpoint and a means of earlier…
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Journal Article
Factors Contributing to Obesity Among Indigenous Peoples of Canada: A Narrative Review
Purpose of Review Obesity is a major and growing public health concern in Canada and an important contributor to chronic kidney disease (CKD). Indigenous Peoples in Canada experience a disproportionately high burden of obesity and CKD, driven by complex social, cultural, environmental, and…
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Journal Article
Behavior-Based Screening in Organ and Tissue Donor Risk Assessments in Two-Spirit, Gay, Lesbian, Bisexual, Transgender, Queer, Intersex and Other Sexual and Gender Minority (2S/LGBTQI+) People: A Canada-wide Community Survey
Purpose Two-Spirit, Lesbian, Gay, Bisexual, Transgender, Queer, Intersex and other sexually and gender diverse (2S/LGBTQI+) populations experience discriminatory donor risk assessments in the Canadian organ and tissue donation (OTD) system. Based on identity and/or sexual behavior many 2S/LGBTQI+…
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Journal Article
A Decade of Peritoneal Dialysis Attrition: A Single-Centre Canadian Retrospective Cohort Study
Background Peritoneal dialysis (PD) attrition is commonly used as a marker of program quality. However, all-cause attrition encompasses competing outcomes including transplantation, death, and technique failure, which carry fundamentally different clinical and programmatic implications…
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Journal Article
Environmental Scan of Digital Access Infrastructure in Canadian Hemodialysis Units for People Receiving In-Center Hemodialysis: A Research Letter
Many people receiving dialysis seek out health-related information online, including through social media, which offers increasing patient education opportunities. The medical community should leverage these possibilities to develop educational resources, while ensuring equitable access. Using…
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Journal Article
Methods for Addressing Missing Patient-Reported Outcome Data in Longitudinal Clinical Trials: A Secondary Analysis of the Frequent Hemodialysis Network Trials
Background Patient-reported outcomes from longitudinal clinical trials on hemodialysis typically have missing data, yet there is a lack of empirical evidence to guide appropriate analysis and interpretation. Objective To compare approaches for analysis and interpretation of patient-reported…
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Journal Article
Canadian Society of Nephrology Commentary on the 2025 Kidney Disease Improving Global Outcomes Clinical Practice Guidelines for Autosomal Dominant Polycystic Kidney Disease
Purpose of review 1) Provide a Canadian perspective on the 2025 Kidney Disease Improving Global Outcomes (KDIGO) Autosomal Dominant Polycystic Kidney Disease (ADPKD) guidelines; 2) identify challenges and nuances in applying these guidelines in Canada; 3) highlight shifts in expert practice points…
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Journal Article
Barriers and Facilitators for Sodium-Glucose Cotransporter-2 Inhibitor Uptake and Implementation in Australia – Perspectives From Clinicians and Patients: An Interview Study
Background While sodium-glucose cotransporter-2 (SGLT2) inhibitors provide major benefits across multiple chronic diseases, clinician prescription and patient adherence rates remain low. Objective To explore perspectives of clinician and patient stakeholders regarding barriers and facilitators for…
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Journal Article
Effects of Increasing the Concentration of Dialysate Magnesium on Cardiovascular Health: A Narrative Review
Purpose of review: Cardiovascular disease (CVD) accounts for nearly half of deaths among people receiving maintenance hemodialysis. Observational and interventional data suggest that higher serum magnesium, achieved through higher dialysate magnesium concentrations or oral supplementation, may…
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Journal Article
Communication Experiences of Patients With Hearing Loss During Hemodialysis Treatment and the Potential Role of Communication Tools: A Qualitative Study
Background: People with hearing loss may have difficulty communicating with health care providers if not properly supported. Hearing loss is common among people with kidney failure. Outpatient hemodialysis centers may present communication barriers due to noisy machines and overlapping…
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Journal Article
Overlap of PR3-Positive ANCA-Associated Vasculitis and Primary Focal Segmental Glomerulosclerosis: A Case Report, Patient Perspective, and Review of the Literature
Anti-neutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) and primary focal segmental glomerulosclerosis (FSGS) are distinct glomerular diseases that rarely occur together. When present concurrently, they may produce overlapping nephritic and nephrotic features that complicate…
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Journal Article
Association Between Sex and Kidney Transplant Referral, Living Donor Contacts, Waitlisting and Kidney Transplant: A Population-Based Cohort Study
Background Studies from several jurisdictions suggest that compared to male individuals, female individuals are less likely to get placed on the waiting list for kidney transplantation and less likely to receive a transplant. However, we poorly understand where sex disparities arise within four key…
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Journal Article
Tertiary Lymphoid Structure–Like Lymphocyte Aggregate Generation in Human and Mouse Hypokalaemic Nephropathy: Research Letter
Potassium (K + ) is an essential ion that keeps the cells and organs functioning properly. Systemic K + deficiency occasionally leads to kidney damage, known as hypokalaemic nephropathy (HN). Hypokalaemic nephropathy is commonly treated with K + supplementation; however, the long-term prognosis of…
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Journal Article
Aligning Practice With Guidelines: A Canadian National Survey and Canadian Society of Nephrology Commentary on the 2025 KDIGO Pediatric Nephrotic Syndrome Recommendations
Purpose of Review The purpose of this commentary is to review the 2025 Kidney Disease Improving Global Outcomes (KDIGO) clinical practice guidelines on the management of childhood nephrotic syndrome (NS) within the Canadian context and based on current practices across the country. Sources of…
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Journal Article
Addition of a Home Hemodialysis Counseling Scenario to an Existing Formative Objective Structured Clinical Examination (OSCE) for Nephrology Fellows: A Research Letter
Background: Home hemodialysis (HHD) prevalence is low in the United States; thus, nephrology fellows may have limited HHD clinical experience and be hesitant to counsel suitable patients. We describe a formative HHD counseling simulation scenario, part of a previously described nephrology-specific…
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Journal Article
Integrated, Community-Led, Culturally Safe Implementation of a Chronic Kidney Disease Detection Program for Indigenous Communities of Canada: The Kidney Check Program Report
Purpose of program: Indigenous peoples in Canada experience a disproportionate burden of chronic kidney disease (CKD) yet face systemic, geographic, and cultural barriers to early detection and care. The Kidney Check program was established as a national initiative to address this gap by providing…
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Journal Article
Program Report: Implementing Mental Health Supports and Resources for Dialysis Patients Into Practice Through the Mind the Gap Project
Purpose of Program People receiving dialysis experience a high burden of mental health challenges. Few dialysis-specific resources exist to support their mental well-being. The Can-SOLVE CKD Network ‘Mind the Gap’ project team identified mental health care challenges for the dialysis population and…
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Journal Article
Progression of Early Kidney Injury in Youth With Type 2 Diabetes: A Follow-Up Analysis From the Canadian iCARE Cohort
Background Youth with type 2 diabetes (T2D) have high rates of albuminuria, the earliest marker of kidney injury in youth with T2D. Later stages of diabetic kidney disease are characterized by increasing albuminuria and declining estimated glomerular filtration rate (eGFR). Mental health and stress…