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Military Medical Research
Scopus
ISSN 2054-9369 · KeAi Communications Co., Ltd. · 572 artikel di indeks
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Artikel Jurnal
Artificial intelligence in digital pathology diagnosis and analysis: technologies, challenges, and future prospects
Abstract Artificial intelligence (AI) offers transformative potential in pathology, where histopathological images remain the diagnostic gold standard due to their rich morphological and molecular information. While the rapid development of AI-driven computational pathology tools is revolutionizing…
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Artikel Jurnal
Diagnostic efficacy of fecal-based miR-92a for advanced colorectal neoplasia: a prospective multicenter screening trial
Abstract Background More efficacious, noninvasive screening methods are needed for advanced colorectal neoplasia. miR-92a is a reliable and reproducible biomarker for early colorectal cancer detection in stool samples. We compared the diagnostic efficacies of miR-92a, immunochemical fecal occult…
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Artikel Jurnal
Social jetlag elicits fatty liver via perturbed circulating prolactin rhythm-mediated circadian remodeling of hepatic lipid metabolism
Abstract Background The prevalence of circadian misalignment, particularly social jetlag (SJL), contributes significantly to the epidemic of metabolic disorders. However, the precise impact of SJL on the liver has remained poorly elucidated. Methods The rhythmicity of circulating prolactin (PRL)…
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Artikel Jurnal
Exploring the diagnostic potential: magnetic particle imaging for brain diseases
Abstract Brain diseases are characterized by high incidence, disability, and mortality rates. Their elusive nature poses a significant challenge for early diagnosis. Magnetic particle imaging (MPI) is a novel imaging technique with high sensitivity, high temporal resolution, and no ionizing…
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Artikel Jurnal
Metal-based nanomedicines for cancer theranostics
Abstract The heterogeneity and invasiveness of cancer cells pose serious challenges in cancer diagnosis and treatment. Advancements and innovations in metal-based nanomedicines provide novel avenues for addressing these challenges. Metal-based nanomedicines possess unique physicochemical properties…
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Artikel Jurnal
Evaluation and application of an innovative portable field endoscope: addressing battlefield and biosafety concerns
Abstract Background At present, no commercially available endoscopic system is specifically designed for use in the battlefield, disaster relief, or unique environments with biosafety concerns. Therefore, this limitation stems from challenges such as limited portability, reliance on stable power…
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Artikel Jurnal
Performance of GPT-4 for automated prostate biopsy decision-making based on mpMRI: a multi-center evidence study
Abstract Background Multiparametric magnetic resonance imaging (mpMRI) has significantly advanced prostate cancer (PCa) detection, yet decisions on invasive biopsy with moderate prostate imaging reporting and data system (PI-RADS) scores remain ambiguous. Methods To explore the decision-making…
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Artikel Jurnal
Clinical information prompt-driven retinal fundus image for brain health evaluation
Abstract Background Brain volume measurement serves as a critical approach for assessing brain health status. Considering the close biological connection between the eyes and brain, this study aims to investigate the feasibility of estimating brain volume through retinal fundus imaging integrated…
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Artikel Jurnal
Epileptic seizure biophysics: the role of local voltage difference
Abstract Background Epilepsy is a neurological disorder characterized by recurrent seizures due to hyperexcitable neuronal network activity. The manifestations vary widely, ranging from subtle sensory disturbances to profound alterations of consciousness, depending on which brain regions are…
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Artikel Jurnal
TNC-targeted CAR-macrophage therapy alleviates liver fibrosis in mice
Abstract Background Tenascin-C (TNC) is an extracellular matrix (ECM) protein involved in tissue damage and fibrosis. Chimeric antigen receptor (CAR) cell therapy is a novel therapeutic approach that has attracted increasing attention in recent years. Here, we engineered CAR-macrophages targeting…
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Artikel Jurnal
MELK prevents radiofrequency ablation-induced immunogenic cell death and antitumor immune response by stabilizing FABP5 in hepatocellular malignancies
Abstract Background Radiofrequency ablation (RFA) is an efficient treatment with unlimited potential for liver cancer that can effectively reduce patient mortality. Understanding the biological process related with RFA treatment is important for improving treatment strategy. This study aimed to…
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Artikel Jurnal
Strategies for promoting neurovascularization in bone regeneration
Abstract Bone tissue relies on the intricate interplay between blood vessels and nerve fibers, both are essential for many physiological and pathological processes of the skeletal system. Blood vessels provide the necessary oxygen and nutrients to nerve and bone tissues, and remove metabolic waste…
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Artikel Jurnal
γ neuromodulations: unraveling biomarkers for neurological and psychiatric disorders
Abstract γ neuromodulation has emerged as a promising strategy for addressing neurological and psychiatric disorders, particularly in regulating executive and cognitive functions. This review explores the latest neuromodulation techniques, focusing on the critical role of γ oscillations in various…
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Artikel Jurnal
Global patterns and trends in cancer-related premature death and their impact on life expectancy across 185 countries: a population-based analysis
Abstract Background The level of premature deaths (deaths among those aged 30–69 years) caused by cancer is an important indicator of evaluating the level of cancer prevention and control. However, the current burden and temporal trends in cancer-related premature deaths, and their impact on life…
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Artikel Jurnal
Substantia nigra related gene polymorphisms associated with antipsychotic-induced acute movement disorders: a genome-wide association study and multi-ancestry validation in schizophrenia
Abstract Background Antipsychotic-induced movement disorders (AIMDs) are prevalent side effects of antipsychotics, particularly during the acute phase of treatment. This study aimed to elucidate the genetic mechanisms underlying AIMDs using a genome-wide association study (GWAS). Methods GWASs on…
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Artikel Jurnal
Glucocorticoids trigger muscle-liver crosstalk to attenuate acute liver injury and promote liver regeneration via the FGF6-FGFBP1 axis
Abstract Background Acute liver injury (ALI) requires rapid hepatic regeneration to avert fatal liver failure. As key mechanisms, systemic metabolic remodeling and inter-organ crosstalk are critical for this regenerative process. Skeletal muscle, as a major metabolic organ system, undergoes…
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Artikel Jurnal
High-salt-driven gut microbiota dysfunction aggravates prostatitis by promoting AHR/SGK1/FOXO1 axis-mediated Th17 cell differentiation
Abstract Background Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a frequently encountered disorder characterized by voiding symptoms and pelvic or perineal pain. Proinflammatory T helper 17 (Th17) cells are essential for triggering the development of CP/CPPS. High-salt diet (HSD)…